Description and Brand Names

Drug information provided by: Micromedex

US Brand Name

  1. Afinitor
  2. Afinitor Disperz
  3. Zortress

Descriptions


Everolimus is used to treat advanced (late-stage) kidney cancer in patients who have already been treated with other medicines (eg, sorafenib, sunitinib) that did not work well.

Everolimus belongs to the group of medicines known as antineoplastics or cancer medicines. It works by interfering with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected, other unwanted effects will also occur. Some of these may be serious and must be reported to your doctor, while others may cause concern but may not be serious.

Everolimus is used together with other medicines to lower the body's natural immunity in patients who receive kidney or liver transplants. When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. Everolimus works to suppress the immune system and prevents the white blood cells from getting rid of the transplanted organ.

This medicine is used to treat subependymal giant cell astrocytoma (SEGA, a brain tumor) and angiomyolipoma (a non-cancerous kidney tumor). These tumors frequently occur in patients with an inherited condition called tuberous sclerosis complex (TSC).

Everolimus is used to treat advanced (late-stage) pancreatic neuroendocrine tumors (PNET, a cancer in the pancreas that spreads to the nervous system) that cannot be treated with surgery.

This medicine is used together with exemestane to treat advanced (late-stage) hormone receptor-positive, HER-2 negative breast cancer in postmenopausal women who have already received other medicines (eg, anastrozole, letrozole) that did not work well.

Before you begin treatment with everolimus, you and your doctor should talk about the benefits of this medicine as well as the risks of using it.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet for Suspension
  • Tablet