Description and Brand Names

Drug information provided by: Micromedex

US Brand Name

  1. Afinitor
  2. Afinitor Disperz
  3. Zortress


Everolimus is used to treat advanced (late-stage) kidney cancer in patients who have already received other medicines that did not work well. It is also used to treat subependymal giant cell astrocytoma (SEGA; a brain tumor), renal angiomyolipoma (a non-cancerous kidney tumor), and advanced (late-stage) pancreatic neuroendocrine tumors (PNET; a pancreas tumor that spreads to the nervous system) that will not be treated with surgery. Everolimus is used together with exemestane to treat advanced (late-stage) hormone receptor-positive, HER-2 negative breast cancer in postmenopausal women who have already received other medicines that did not work well.

Everolimus works by interfering with the growth of cancer cells, which are eventually destroyed by the body. Since the growth of normal body cells may also be affected, other unwanted effects will also occur. It belongs to the group of medicines known as antineoplastics (cancer medicines).

Everolimus is also used together with other medicines to lower the body's natural immunity in patients who receive kidney or liver transplants. When a patient receives an organ transplant, the body's white blood cells try to get rid of (reject) the transplanted organ. Everolimus works to suppress the immune system and prevents the white blood cells from getting rid of the transplanted organ.

Before you begin treatment with everolimus, you and your doctor should talk about the benefits of this medicine as well as the risks of using it.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet for Suspension
  • Tablet