Sepsis ranges from less to more severe. As sepsis worsens, blood flow to vital organs, such as your brain, heart and kidneys, becomes impaired. Sepsis can also cause blood clots to form in your organs and in your arms, legs, fingers and toes — leading to varying degrees of organ failure and tissue death (gangrene).
Most people recover from mild sepsis, but the mortality rate for septic shock is nearly 50 percent. Also, an episode of severe sepsis may place you at higher risk of future infections.
July 23, 2014
- Maloney PJ. Sepsis and septic shock. Emergency Medicine Clinics of North America. 2013;31:583.
- McKean SC, et al. Principles and Practice of Hospital Medicine. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=749. Accessed May 27, 2014.
- Tintinalli JE, et al. Tintinalli's Emergency Medicine: A Comprehensive Study Guide. 7th ed. New York, N.Y.: The McGraw Hill Companies; 2011. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=40. Accessed May 27, 2014.
- Neviere R. Sepsis and the systemic inflammatory response syndrome: Definitions, epidemiology, and prognosis. http://www.uptodate.com/home. Accessed May 28, 2014.
- Angus DC, et al. Severe sepsis and septic shock. New England Journal of Medicine. 2013;369:840.
- Mandell GL, et al. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2010. https://www.clinicalkey.com. Accessed May 27, 2014.