How important are non-HDL cholesterol and cholesterol ratio?

For predicting your risk of heart disease, many healthcare professionals now believe that determining your non-HDL cholesterol level may be more useful than calculating your cholesterol ratio. And either of those two options seems to be a better risk predictor than your total cholesterol level or your low-density lipoprotein (LDL) cholesterol level, known as the "bad" cholesterol.

As the name implies, the non-HDL cholesterol level simply subtracts your high-density lipoprotein (HDL) cholesterol, known as the "good" cholesterol, number from your total cholesterol number. So the non-HDL number includes all the bad types of cholesterol.

An optimal level of non-HDL cholesterol for most people is less than 130 milligrams per deciliter (mg/dL), which is 3.37 millimoles per liter (mmol/L). For people with a history of heart attack, the desired level may be lower. Higher numbers mean a higher risk of heart disease.

To calculate your cholesterol ratio, divide your total cholesterol number by your HDL cholesterol number. So if your total cholesterol is 200 mg/dL (5.2 mmol/L) and your HDL is 50 mg/dL (1.3 mmol/L), your ratio would be 4-to-1. Higher ratios mean a higher risk of heart disease.

From Mayo Clinic to your inbox

Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview.

We use the data you provide to deliver you the content you requested. To provide you with the most relevant and helpful information, we may combine your email and website data with other information we have about you. If you are a Mayo Clinic patient, we will only use your protected health information as outlined in our Notice of Privacy Practices. You may opt out of email communications at any time by clicking on the unsubscribe link in the email.

Jan. 12, 2024 See more Expert Answers