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  1. Tonia M. Young-Fadok, M.D.

    Tonia M. Young-Fadok, M.D.

    1. Colon and Rectal Surgeon
    1. Phoenix, AZ
    擅长领域:

    Colostomy, Colorectal surgery, Active surveillance, Colon cancer surgery, Rectal cancer surgery, Ulcerative colitis, Cr...ohn's disease, Colon cancer, Rectal cancer, Colon polyps, Diverticulitis, Anal fistula

研究

Designated as a comprehensive cancer center by the National Cancer Institute, Mayo Clinic Comprehensive Cancer Center is defining new boundaries in rectal cancer research.

Areas of research include:

  • Personalized cell therapy. The goal of this study is to build a library of rectal cancer cells taken from patients, which can be used to develop more-personalized treatment strategies.
  • Robotic versus laparoscopic surgery. This study compares robotic and conventional laparoscopic surgery for rectal cancer by assessing how each approach affects bowel, urinary and sexual function after surgery.
  • Presurgery treatment. This study compares two treatments for rectal cancer before surgery — standard chemotherapy with radiation versus chemotherapy alone — to see which works better and causes fewer side effects.

Publications

See a list of publications about rectal cancer by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

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Aug. 13, 2025
  1. Clark S, et al., eds. Surgery for rectal cancer. In: Colorectal Surgery: A Companion to Specialist Surgical Practice. 7th ed. Elsevier; 2024. https://www.clinicalkey.com. Accessed July 23, 2025.
  2. Cameron JL, et al., eds. Management of rectal cancer. In: Current Surgical Therapy. 14th ed. Elsevier; 2023. https://www.clinicalkey.com. Accessed July 23, 2025.
  3. Rectal cancer treatment (PDQ) — Health professional version. National Cancer Institute. https://www.cancer.gov/types/colorectal/hp/rectal-treatment-pdq. Accessed July 23, 2025.
  4. Irani JL, et al. Clinical practice guidelines for enhanced recovery after colon and rectal surgery from the American Society of Colon and Rectal Surgeons and the Society of American Gastrointestinal and Endoscopic Surgeons. Surgical Endoscopy. 2023; doi:10.1007/s00464-022-09758-x.
  5. Langenfeld SJ, et al. The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of rectal cancer 2023 supplement. Diseases of the Colon and Rectum. 2024; doi:10.1097/DCR.0000000000003057.
  6. Rectal cancer. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1461. Accessed June 30, 2025.
  7. ACR appropriateness criteria: Staging and disease monitoring of rectal cancer. American College of Radiology. https://acsearch.acr.org/docs/3195870/Narrative. Accessed June 30, 2025.
  8. Donovan KF, et al. Transanal total mesorectal excision for rectal cancer. Advances in Surgery. 2025; doi:10.1016/j.yasu.2025.04.004.0065-3411/25.
  9. Dowli A, et al. Primary colorectal cancer. Surgery Oncology Clinics of North America. 2023; doi:10.1016/j.soc.2022.08.002.
  10. Donohue K, et al. Local excision for early-stage rectal adenocarcinomas. Cancer Journal. 2024; doi:10.1097/PPO.0000000000000734.
  11. Bleday R, et al. Surgical treatment of rectal cancer. https://www.uptodate.com/contents/search. Accessed June 30, 2025.
  12. Surgery for rectal cancer. American Cancer Society. https://www.cancer.org/cancer/types/colon-rectal-cancer/treating/rectal-surgery.html. Accessed July 23, 2025.
  13. Semanjski K, et al. Current surgical methods in local rectal excision. Gastrointestinal Tumors. 2024; doi:10.1159/000538958.
  14. Types of surgery for rectal cancer. Cancer Research UK. https://www.cancerresearchuk.org/about-cancer/bowel-cancer/treatment/treatment-rectal/surgery-rectal/types-surgery-rectal. Accessed July 23, 2025.
  15. Health Education & Content Services. Colon and rectal cancer. Mayo Clinic; 2023.
  16. Health Education & Content Services. Combination treatment for advanced rectal cancer. Mayo Clinic; 2023.
  17. Cameron JL, et al., eds. Surgical management of the polyposis syndromes. In: Current Surgical Therapy. 14th ed. Elsevier; 2023. https://www.clinicalkey.com. Accessed July 23, 2025.
  18. Ahmad SA, et al., eds. Inherited colorectal cancer and the genetics of colorectal cancer. In: Shackelford's Surgery of the Alimentary Tract. 9th ed. Elsevier; 2026. https://www.clinicalkey.com. Accessed July 23, 2025.
  19. You NY, et al. The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of rectal cancer. Diseases of the Colon and Rectum. 2020; doi:10.1097/DCR.0000000000001762.
  20. Harris KM. Allscripts EPSi. Mayo Clinic. July 29, 2025.
  21. Medical review (expert opinion). Mayo Clinic. July 30, 2025.

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