医疗专业人员

下面列出了当前开展的临床试验。

根据地点、状态和其他条件对此研究列表进行过滤。

1. Early Naturalistic Hands-on Autism Caregiver Training

   Rochester, Minn.

   The purpose of this study is to pilot test the ENHANCE intervention to evaluate methodology, feasibility based on caregiver input, and preliminary caregiver satisfaction. The primary outcomes will be feedback from parents, participant completion/atrition rates, the interventionist study log, and interventionist/caregiver/fidelity. Second, we aim to examine preliminary impact of the naturalistic intervention on child social communication and repetitive behavior in order to estimate clinically meaningful change for future research studies. 

2. A Study to Develop Liquid Biopsy for Pediatric Brain Tumor Patients

   Rochester, Minn.

   The purpose of this study is to confirm detection of the H3K27M mutation in patient biofluids (CSF, blood, urine, saliva) and uncover the molecular histone (alkaline protein) profile of H3K trimethylation and H3S phosphorylation in the circulating nucleosomes isolated from the biofluids of patients with H3K27M tumors.

3. Hypoplastic Left Heart Syndrome: Validating Functional Parameters and Novel Echocardiographic Imaging Strategies for Evaluation of Functionally Single Right Ventricular Performance using Previously Recorded Studies

   Rochester, Minn.

   The purpose of this study is to validate novel echocardiographic parameters and algorithms to quantitatively evaluate right ventricular function in patients with Hypoplastic Left Heart Syndrome (HLHS) by applying these methods to previously acquired echocardiographic examinations. 

4. A Study to Form a Database of Children with Kidney Stone Disease

   Rochester, Minn.

   The purpose of this study is to establish a database to collect and analyze information on metabolic and environmental risk factors for kidney stone formation in children.

5. A Registry to Follow Long-Term Outcomes for Mother and Child Pairs After Fetal Surgery for Spina Bifida

   Rochester, Minn.

   The purpose of this study is to form a registry of data on the long term physical and mental health outcomes of the mother and child following fetal surgical repair for spina bifida.

6. A Study to Analyze Surgical Outcomes and Predictors of Treatment for Hip Diseases

   Rochester, Minn.

   This study is designed to:
   -analyze effects of surgical treatment
   -improve surgical care and quality of life of patients with hip problems/diseases
   -ID predictors of surgical outcomes to identify/improve future treatments
   -Collect data, images, from patients undergoing surgical treatment of hip disorders (we will not be collecting social security numbers to send to Washington University).

7. A Registry Called Every Child for Collecting Data and Biology Specimens on Younger Patients with Cancer

   Rochester, Minn.

   The purpose of this registry called Every Child, is to collect data and biospecimens from multiple body sources for younger patients with cancer over time. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.

8. A Study to Establish a Registry for Treatment of Post-hemorrhagic Hydrocephalus in Neonates

   Rochester, Minn.

   The purpose of this study is to establish a prospective, standardized data collection for the patients who undergo surgical treatment of progressive post-hemorrhagic hydrocephalus in neonates with the focus on comparing neuroendoscopic lavage (NEL) with other standard treatment options such as external ventricular drainage (EVD), ventricular access device (VAD) and ventricular subgaleal shunt (VSGS).

9. A Study of the Effects of Preterm Birth on Lung Disease and Innate Immunity Later in Life

   Rochester, Minn.

   The primary purpose of this study is to investigate the cytokine responses of blood ILC2s from preterm children by collecting peripheral blood at age 5-10 years from children born either preterm or at term, and to analyze the functions of their circulating ILC2s in vitro.

    

10. Happigenius Social-Emotional Learning Curriculum in Rochester Public Schools

    Rochester, Minn.

    The purpose of this study is to test the effectiveness of HappiGenius curriculum in 3rd grade students attending elementary school in the Rochester Public Schools system (Rochester, MN). Convenience samples are selected from students in classrooms receiving the HappiGenius curriculum in their normal school curriculum and students in classrooms that have opted not to have HappiGenius in their classroom this term. For the study, questionnaires will be administered at the start and conclusion of HappiGenius lessons to determine whether HappiGenius curriculum delivers the core competencies of improved attention, positive affect, self-awareness, sociality, and self-kindness.