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    4. Crohn’s Disease Treatment

    Crohn's Disease Treatment

    At Mayo Clinic Healthcare London, our gastroenterology specialists assess and treat inflammatory bowel conditions, including Crohn’s disease. If you have ongoing digestive symptoms, our team can help identify the cause and recommend the most appropriate treatment plan for you.

    Crohn’s disease is a long-term inflammatory bowel disease (IBD) that causes inflammation in the digestive tract. Symptoms can vary widely between individuals, so accurate diagnosis and ongoing monitoring are important parts of care.

    Your assessment may include advanced diagnostic testing to evaluate inflammation, confirm diagnosis and guide treatment recommendations tailored to your symptoms and long-term health needs.

    • Crohn’s disease is a long-term inflammatory condition that causes swelling and irritation in the digestive tract. It most commonly affects the small intestine and colon, although inflammation can affect any part of the digestive tract, from the mouth to the anus. 

      Inflammation caused by Crohn's disease may involve deeper layers of the bowel wall and can lead to digestive symptoms, nutritional deficiencies, and complications over time. 

    • Crohn’s disease symptoms may include:

      • Persistent diarrhoea 
      • Abdominal pain and cramping 
      • Blood in the stool 
      • Fatigue 
      • Weight loss 
      • Reduced appetite 
      • Fever

      Symptoms may develop gradually or appear suddenly, and they can range from mild to severe. You may have periods when symptoms improve or disappear (remission), followed by flare-ups.  

      Without treatment and ongoing monitoring, Crohn’s disease can lead to complications such as bowel narrowing, fistulas (abnormal connections between parts of the intestine or nearby organs), malnutrition, or abscess formation.

    • The exact cause of Crohn’s disease is not fully understood, but it is thought to involve a combination of immune, genetic, and environmental factors. 

      Risk factors may include: 

      • Family history of inflammatory bowel disease 
      • Smoking 
      • Changes in how the immune system functions 
      • Environmental triggers 

      Crohn’s disease may occur when the immune system mistakenly attacks healthy tissue in the digestive tract, leading to ongoing inflammation.

    • You should seek specialist medical advice if you experience persistent or worsening digestive discomfort, or if you have:

      • Persistent diarrhoea lasting more than a few days or comes back frequently
      • Ongoing abdominal pain or cramping
      • Unexplained weight loss
      • Blood in your stool or rectal bleeding
      • Ongoing fatigue or low energy 
      • Reduced appetite or difficulty maintaining nutrition
      • Symptoms that occur in flare-ups

      You should seek urgent medical attention if you experience:

      • Severe abdominal pain
      • Signs of dehydration (dizziness, very dry mouth, reduced urination)
      • High fever alongside digestive symptoms
      • Significant or ongoing rectal bleeding

      Because Crohn’s disease symptoms can overlap with other conditions such as irritable bowel syndrome (IBS) or infections, early specialist evaluation is essential to confirm the diagnosis and begin appropriate testing for Crohn disease and tailored Crohn’s disease treatment.

    • At Mayo Clinic Healthcare London, testing for Crohn’s disease begins with a detailed clinical assessment. Your consultant will review your symptoms, medical history and any previous test results before recommending further investigations. 

      Investigations may include:

      • Blood tests: to check for inflammation, anaemia, or infection 
      • Stool testing: to assess intestinal inflammation 
      • Colonoscopy: to examine the bowel lining and obtain biopsies 
      • MRI or CT scans: to assess inflammation and complications within the digestive tract

      Accurate testing for Crohn’s disease is essential because symptoms can overlap with other digestive conditions, including ulcerative colitis and irritable bowel syndrome.

    • Your consultation will focus on understanding your symptoms and their impact on your daily life. 

      Your consultation may include:

      • A detailed discussion of digestive symptoms and flare patterns 
      • Review of diet, medications, and family history 
      • Physical examination where appropriate 
      • Recommendations for diagnostic testing 
      • Discussion of treatment and monitoring options

      Our specialists provide clear explanations and coordinated care throughout your diagnosis and treatment. 

    • Crohn’s disease treatment is focused on reducing inflammation, controlling symptoms, and preventing complications. 

      Your Crohn’s disease treatment plan may include: 

      • Anti-inflammatory medication 
      • Immune-modifying therapies 
      • Nutritional support 
      • Dietary and lifestyle guidance
      • Monitoring with repeat imaging or endoscopy 

      Your treatment plan depends on where inflammation occurs, how severe it is, and how your symptoms affect your daily life.

    • At Mayo Clinic Healthcare London, our gastroenterology team focuses on delivering clear answers, effective treatment, and ongoing support throughout your care. 

      This includes: 

      • Advanced diagnostic testing and imaging 
      • Personalised Crohn’s disease treatment plans 
      • A collaborative, multidisciplinary model of care 
      • Mayo Clinic’s internationally recognised approach to complex digestive disease 

      Our goal is to provide clarity, symptom control, and support through every stage of care.

    Private health insurance

    We work with all major private health insurers, including AXA PPP, Aviva, Bupa, Health Partners Group, Vitality Health and WPA. Self-pay options are also available, offering flexibility for both UK-based and international patients. 

    Book a Crohn's disease appointment

    If you are experiencing digestive symptoms or require further evaluation, our expert team is here to help. 

    We provide specialist assessments, advanced diagnostics, and individualised Crohn’s disease treatment to support your long-term digestive health. 

    Request an appointment today or call +44 (0) 207 871 2575 to arrange your consultation at Mayo Clinic Healthcare London. 

    Medically Reviewed by

    Dr Sarmed Sami, Consultant Gastroenterologist

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