Jonathan Hill, MBChB, MRCP, FRCP

    Consultant Interventional Cardiologist and Chair of Cardiology


    Expertise

    Dr Jonathan Hill is a Consultant Interventional Cardiologist and Chair of Cardiology at Mayo Clinic Healthcare London. He is one of the United Kingdom's most experienced complex coronary interventionalists, with over 25 years of practice in the diagnosis and treatment of advanced coronary artery disease.

    Dr Hill trained at the University of Edinburgh and the University of Cambridge, before completing subspecialty interventional cardiology training in London and at the National Heart, Lung and Blood Institute (NHLBI) at the National Institutes of Health in Bethesda, Maryland. He has served on the faculty of the world's most prestigious interventional cardiology meetings, including TCT, EuroPCR and the ACC, and has delivered live case demonstrations across Europe, Asia and North America.

    He has an extensive track record in clinical research, having served as Principal Investigator and Steering Committee member on multiple landmark trials in coronary intervention, intracoronary imaging and coronary physiology. He is internationally recognised as one of the foremost authorities on intracoronary OCT and combined imaging and physiology-guided PCI.


    Areas of Focus

    • Complex percutaneous coronary intervention (PCI)
    • Chronic total occlusion (CTO) revascularisation
    • Intracoronary imaging, including optical coherence tomography (OCT) and near-infrared spectroscopy (NIRS)
    • Coronary physiology and functional assessment of coronary stenoses
    • Acute coronary syndromes and high-risk PCI
    • Vulnerable plaque and prevention of coronary events
    • Coronary artery disease in complex and high-risk patients
    • Chest pain, angina and coronary artery disease assessment

    Conditions treated

    • Coronary artery disease and stable angina
    • Acute coronary syndromes (heart attack and unstable angina)
    • Chronic total occlusion (CTO) of coronary arteries
    • Complex multivessel and left main stem coronary artery disease
    • High-risk coronary artery disease in patients with impaired heart function
    • Vulnerable plaque and high-risk non-obstructive coronary disease
    • In-stent restenosis and stent failure
    • Heavily calcified coronary artery disease
    • Chest pain syndromes including microvascular angina
    • Atrial fibrillation and palpitations (assessment)
    • Hypertension and cardiovascular risk
    • Heart failure assessment and optimisation
    • Valvular heart disease (assessment and triage)

    Procedures

    Interventional 

    • Coronary angiography and left heart catheterisation
    • Percutaneous coronary intervention (PCI), including complex, calcified, bifurcation and left main stem procedures
    • Chronic total occlusion (CTO) revascularisation
    •  High-risk PCI with mechanical circulatory support
    • Intracoronary imaging: optical coherence tomography (OCT) and NIRS
    • Coronary physiology: FFR, iFR and angiography-derived functional assessment
    • Intravascular Lithotripsy (Shockwave)
    • Rotational atherectomy (Rotablation)

    Diagnostic

    • CT coronary angiography and CT-guided intervention planning
    • Echocardiography (assessment and interpretation)
    • Exercise stress testing and cardiopulmonary exercise testing
    • Ambulatory ECG monitoring and 12-lead ECG
    • Cardiac MRI (clinical assessment and interpretation)
    • 24-hour ambulatory blood pressure monitoring

    Education

    • MBChB, University of Edinburgh Medical School (1992)
    • Pre-clinical studies, University of Cambridge
    • General Medical Training, Royal Brompton and Harefield Hospital, London
    • Cardiology Specialist Training, London Chest Hospital and Barts
    • Visiting Scientist, Laboratory of Molecular Biology, NHLBI/NIH, Bethesda, Maryland
    • Visiting Scientist, Cardiovascular Intervention Program, NHLBI/NIH, Bethesda, Maryland
    • Senior Interventional Fellow, London Chest Hospital and Barts
    • Certificate of Completion of Specialist Training (CCST), Cardiology
    • MRCP, Royal College of Physicians
    • FRCP, Fellow of the Royal College of Physicians

    Research

    Dr Hill's research interests include intracoronary imaging and its role in guiding percutaneous coronary intervention, coronary physiology and functional assessment, the identification and treatment of vulnerable plaque, interventional approaches to cardiogenic shock, and the integration of artificial intelligence and advanced imaging in cardiovascular medicine.

    A particular focus of his research is the management of heavily calcified coronary artery disease. Dr Hill was one of the earliest clinical investigators in intravascular lithotripsy (IVL), a technology that uses sonic pressure waves to modify calcified plaque and improve stent delivery and expansion in complex coronary lesions. He served as a Principal Investigator on the pivotal IDE study that supported FDA approval of coronary IVL and was instrumental in establishing the evidence base that contributed to the global adoption of this technology. He continues to contribute to research in calcium characterisation and modification, with a particular interest in the use of intracoronary imaging to guide calcium preparation strategies.

    Dr Hill has a longstanding interest in the management of high-risk and haemodynamically compromised patients undergoing complex coronary intervention. He has been closely involved in the clinical development and investigation of percutaneous mechanical circulatory support, including the use of microaxial left ventricular assist devices to support patients with cardiogenic shock and severely impaired cardiac function during high-risk procedures. He is the founder of SHOCK-LONDON-1, a multicentre cardiogenic shock registry, and has been involved in the design of clinical programmes aimed at improving outcomes for this high-risk patient population.

    He has served as Principal Investigator and Steering Committee member on multiple international clinical trials and registries and has published in leading peer-reviewed journals.


    Honours

    • Outstanding Fellows Award, NIH/NHLBI
    • Young Clinical Investigator Award Finalist, American Heart Association
    • Young Investigator Award, European Society of Cardiology
    • Young Investigator Award, American College of Cardiology
    • Bench to Bedside Award, Fogarty International Center, National Institutes of Health
    • London Interventional Fellows Award, London Hospitals PCI Group
    • NIHR Leading Commercial Principal Investigator, National Institute for Health Research

    Professional memberships

    • Fellow, Royal College of Physicians (FRCP)
    • Member, Royal College of Physicians (MRCP)
    • General Medical Council, United Kingdom — Full Registration
    • British Cardiovascular Intervention Society (BCIS)
    • British Cardiovascular Society (BCS)
    • American College of Cardiology (ACC)
    • European Society of Cardiology (ESC)

    Languages

    • English