Description and Brand Names

Drug information provided by: Merative, Micromedex®

US Brand Name

  1. Alkeran IV
  2. Evomela


Melphalan injection is used to treat multiple myeloma (bone marrow cancer) before receiving a stem cell transplant (conditioning treatment). Melphalan belongs to the group of medicines called alkylating agents (cancer medicines). It works by interfering with the growth of cancer cells, which are eventually destroyed by the body. Since the growth of normal cells may also be affected by melphalan, other unwanted effects will also occur. Before you begin treatment with melphalan, talk to your doctor about the benefits as well as the risks of using it.

Melphalan injection is also used to treat uveal melanoma (eye cancer) that has spread to the liver and cannot be removed by surgery (unresectable liver metastases).

Evomela®, Alkeran®, and Melphalan injection are to be given only by or under the direct supervision of your doctor. Hepzato® injection is available only under a restricted distribution program called Hepzato® Kit REMS (Risk Evaluation and Mitigation Strategy) Program.

This product is available in the following dosage forms:

  • Powder for Solution