Stages Escrito por el personal de Mayo Clinic If you're diagnosed with non-Hodgkin lymphoma, the next step is to determine the cancer's extent, called the stage. Imaging tests, blood tests and biopsies may be used to determine the stage of your non-Hodgkin lymphoma. Your healthcare team uses the cancer stage to help create your treatment plan. The stages of non-Hodgkin lymphoma range from 1 to 4: Stage 1 non-Hodgkin lymphoma. At this stage, only one lymph node region or one site outside of the lymph nodes is affected. Stage 2 non-Hodgkin lymphoma. Stage 2 involves two or more lymph node regions on the same side of the diaphragm. Stage 3 non-Hodgkin lymphoma. At stage 3, lymph node regions on both sides of the diaphragm or lymph nodes above the diaphragm and the spleen are affected. Stage 4 non-Hodgkin lymphoma. At stage 4, non-Hodgkin lymphoma has spread to organs outside of the lymphatic system. Non-Hodgkin lymphoma prognosisThe cancer prognosis tells you how likely it is that the cancer can be treated or cured. Your prognosis may depend on: Your age. Your overall health. The type of non-Hodgkin lymphoma you have. The cancer's stage. Your blood test results. Talk with your healthcare team about your prognosis if you want to know what to expect. Members of your healthcare team can explain what they consider when thinking about your prognosis. Solicite una consulta Diagnóstico y tratamientoSurvival rates Nov. 07, 2025 Comparte en: FacebookTwitter Living with linfoma no Hodgkin? Connect with others like you for support and answers to your questions in the Blood Cancers & Disorders support group on Mayo Clinic Connect, a patient community. Blood Cancers & Disorders Discussions Polycythemia Vera: Just been diagnosed 440 Replies Sat, Nov 15, 2025 chevron-right Has anyone been diagnosed with POEMS syndrome? 18 Replies Sat, Nov 15, 2025 chevron-right Have you ever had hiccups with or after chemotherapy? 121 Replies Fri, Nov 14, 2025 chevron-right See more discussions Mostrar referencias B-cell lymphomas. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1480. Accessed Aug. 30, 2024. T-cell lymphomas. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1483. Accessed Aug. 30, 2024. Non-Hodgkin lymphoma (NHL). Leukemia & Lymphoma Society. https://www.lls.org/lymphoma/non-hodgkin-lymphoma. Accessed Sept. 16, 2024. DeVita VT Jr, et al., eds. Non-Hodgkin lymphoma. In: DeVita, Hellman, and Rosenberg's Cancer: Principles and Practice of Oncology. 12th ed. Wolters Kluwer; 2023. Accessed Aug. 28, 2024. Distress management. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=3&id=1431. Accessed Aug. 29, 2024. Member institutions. Alliance for Clinical Trials in Oncology. https://www.allianceforclinicaltrialsinoncology.org/main/public/standard.xhtml?path=%2FPublic%2FInstitutions. Accessed Sept. 17, 2024. Member institution lists. NRG Oncology. https://www.nrgoncology.org/About-Us/Membership/Member-Institution-Lists. Accessed Sept. 17, 2024. Bock AM, et al. Bispecific antibodies for non-Hodgkin lymphoma treatment. Current Treatment Options in Oncology. 2022; doi:10.1007/s11864-021-00925-1. Tun AM, et al. Immunotherapy in Hodgkin and non-Hodgkin lymphoma: Innate, adaptive and targeted immunological strategies. Cancer Treatment Reviews. 2020; doi:10.1016/j.ctrv.2020.102042. Nowakowski GS, et al. Integrating precision medicine through evaluation of cell of origin treatment planning for diffuse large B-cell lymphoma. Blood Cancer Journal. 2019; doi:10.1038/s41408-019-0208-6. Laurent C, et al. Impact of expert pathologic review of lymphoma diagnosis: Study of patients from the French Lymphopath Network. Journal of Clinical Oncology. 2017; doi:10.1200/JCO.2016.71.2083. Paulson CL. Allscripts EPSi. Mayo Clinic. July 15, 2025. Cancer stat facts: Non-Hodgkin lymphoma. National Cancer Institute. https://seer.cancer.gov/statfacts/html/nhl.html. Accessed Oct. 1, 2025. Non-Hodgkin lymphoma treatment (PDQ) — Patient version. National Cancer Institute. https://www.cancer.gov/types/lymphoma/patient/adult-nhl-treatment-pdq. Accessed Oct. 1, 2025. Elsevier Point of Care. Clinical Overview: Non-Hodgkin lymphoma. https://www.clinicalkey.com. Accessed Oct. 1, 2025. Cancer stat facts: NHL — Diffuse large B-cell lymphoma (DLBCL). National Cancer Institute. https://seer.cancer.gov/statfacts/html/dlbcl.html. Accessed Oct. 1, 2025. Cancer stat facts: NHL — Follicular lymphoma. National Cancer Institute. https://seer.cancer.gov/statfacts/html/follicular.html. Accessed Oct. 1, 2025. Linfoma no HodgkinSíntomasycausasDiagnósticoytratamientoStagesSurvivalratesMédicosydepartamentosAtención enMayoClinic CON-20375662 Enfermedades y afecciones Linfoma no Hodgkin