Medicina del dolor

A continuación se enumeran ensayos clínicos actuales.

Filtrar esta lista de estudios según la ubicación, el estado del estudio y más.

1. A Study to Evaluate Prevalence of Hypogonadism in Patients with Chronic Pain

   Jacksonville, Fla.

   The purpose of this study is to evaluate the hormonal profile related to opioid-induced hypogonadism (OIH) in chronic pain patients before and after completing 3 weeks Interdisciplinary Pain Rehabilitation Program (IPRP) at Pain Rehabilitation Center (PRC) at Mayo Clinic/Florida.

2. A Study of Quality of Life and Pain Control Before and After Endovascular Renal Denervation in Individuals with Refractory Kidney Pain

   Rochester, Minn.

   The purpose of this study is to examine patient reported outcomes including pain, quality of life, depression and impact on kidney blood flow before and after procedure to destroy the pain sensory nerves of the kidneys in patients with untreatable one or two sided kidney pain. We will also collect retrospective data on patientsn who underwent the procedure as clinical care but did not particiapte in the prospective study. 

3. A Study to Evaluate Droperidol Use in the Emergency Department and the Effect on QTc

   Rochester, Minn.

   The purpose of this study is to study the length of the QTc interval in patients receiving the standard of care dose of intravenous droperidol for headache or migraine, nausea, pain, and indications other than agitation over 30 minutes.

4. Magnetic Resonance Elastography of Myofascial Pain Syndrome

   Rochester, Minn.

   The purpose of this study is to develop MRE-based imaging biomarkers to measur the mechanical properties of the myofascial interface and determine if there are changes in these parameters in MPS patients and if these parameters can be used to monitor treatment responses and predict patient outcomes.

    

    

5. Resting State Connectivity in Adolescents with Postural Orthostatic Tachycardia Syndrome and Chronic Pain

   Rochester, Minn.

   The purposes of this study are to compare the functional connectivity in adolescent patients with Postural Orthostatic Tachycardia Syndrome (POTS) both with and without chronic pain, to those with chronic pain alone, to that of healthy controls; to evaluate whether there is a change in functional connectivity following participation in an intensive rehabilitation-oriented program previously demonstrated to have excellent outcomes with regard to functional recovery and symptom control; and to correlate outcomes using standardized symptom and function rating scales to imaging findings.

6. A Study to Assess Study Design and Potential Willingness to Participate in a Future Study of Opioid Tapering

   Eau Claire, Wis., Rochester, Minn.

   The purpose of this study is to administer a survey to elicit interest in participating in a future proposed trial involving a very slow tapering of opioid medications (approximately 10% dose reduction every month) for up to 12 months.

7. Analysis of Spinal Cord Stimulation Usage Over a 15-Year Period

   Scottsdale/Phoenix, Ariz., Rochester, Minn.

   The purpose of this study is to determine the rate at which patients who underwent Spinal Cord Stimulation (SCS) trial ultimately progressed to SCS implantation, determine the percentage of patients who continued using their SCS system after 5 years, as well as identify patient characteristics that lead to SCS discontinuation.

8. A Study of Serum Baclofen Levels in Patients with Intrathecal Baclofen Therapy

   Rochester, Minn.

   The purpose of this study is to determine serum levels of baclofen in patients with spasticity managed with long-term intrathecal baclofen therapy. 

9. A Study to Evaluate Neurostimulation to Treat Chronic Upper Limb Pain After Brachial Plexus Injury

   Rochester, Minn., Jacksonville, Fla.

   This study is designed to assess the degree to which high-frequency spinal cord stimulation may help with pain after brachial plexus avulsion injury.

10. RLY-2608-201-Ph2 Study Of RLY-2608 In PROS And PIK3CA Driven Malformations

    Rochester, Minn.

    The purpose of this study is to compare the efficacy and safety of RLY-2608 versus placebo in adult, adolescent, and pediatric participants with PROS and malformations driven by PIK3CA mutations, which is preceded by a dose selection and basket design with exploratory single-arm cohorts for various subpopulations of participants.