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Brittany L. Siontis, M.D.

  1. Oncologist

Brittany L. Siontis, M.D., is a medical oncologist with specialty interest in soft tissue and bone sarcomas. Her clinical focus includes multidisciplinary care for bone and soft tissue sarcoma, including:

  • Leiomyosarcoma and other soft tissue sarcoma
  • Uterine sarcomas
  • Gastro-intestinal stromal tumor
  • Ewing sarcoma and osteosarcoma
  • Radiation therapy-related sarcoma
  • Desmoid tumor

In addition to her clinical activities, Dr. Siontis is active in research and education. Her research efforts focus on the evaluation of novel therapeutics in bone and soft tissue sarcomas through clinical trials. Dr. Siontis currently serves as the Principal Investigator of several active clinical trials at Mayo Clinic through the Sarcoma Medical Oncology Group. In addition to clinical trials, Dr. Siontis has received funding to evaluate the role of blood and urine-based biomarkers in sarcomas. She has several peer-reviewed publications of her original work and has served as an ad-hoc reviewer of sarcoma-related research for peer-reviewed journals. Dr. Siontis has been an invited speaker in national patient-focused / sarcoma awareness meetings.

  1. 2018
    Fellow - Hematology/OncologyUniversity of Michigan - Ann Arbor
  2. 2015
    ResidentInternal Medicine, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  3. 2012
    MDUniversity of Washington, Seattle
  4. 2008
    MS - BiologyUniversity of Alaska, Fairbanks
  5. 2007
    BS - Biochemistry and Molecular BiologyUniversity of Alaska, Fairbanks


  1. 2018
    Medical OncologyAmerican Board of Internal Medicine
  2. 2015
    Internal MedicineAmerican Board of Internal Medicine

Awards and honors

  1. 2014
    Abstract Achievement AwardAmerican Society of Hematology
  2. 2012
    ExcellenceUniversity of Washington School of Medicine
  3. 2007
    American Institutes of Chemists Award

Professional memberships

  1. 2021 - present
    ChairDivision of Medical Oncology, Department of Oncology
  2. 2019 - present
    Committee MemberDivision of Medical Oncology, Department of Oncology
  3. 2019 - present
    Founding MemberDivision of Medical Oncology, Department of Oncology
  4. 2017 - 2018
    Voting MemberElsa Pardee Foundation Grant Review Committee
  5. 2016 - present
    MemberConnective Tissue Oncology Society
  6. 2015 - present
    MemberAmerican Society of Clinical Oncology
  7. 2012 - 2015
    RepresentativeMayo Internal Medicine Residents' Council
  8. 2008 - present
    MemberAmerican College of Physicians
  9. 2008 - present
    MemberAmerican Medical Association