Profesionales médicos

A continuación, se enumeran los ensayos clínicos actuales.

Filtra esta lista de estudios por sede, estado, etc.

1. Detection of Infection in Arthroplasty

   Rochester, Minn.

   The purpose of this study is to determine the sensitivity, specificity, positive and negative predictive values of molecular detection of microorganisms, detection of microbial proteins and antibodies against microorganisms, and inflammatory markers (e.g., leukocyte esterase, CRP) in synovial fluid for the diagnosis of prosthetic joint infection (PJI).

2. A Blanket Protocol to Study Oral Regorafenib in Patients with Selected Sarcoma Subtypes

   Rochester, Minn., Jacksonville, Fla.

   Regorafenib might or might not slow down the growth of your tumor, or shrink your tumor. Regorafenib is approved in the United States to treat colon cancer and one form of sarcoma (GIST), but we do not know if regorafenib is useful to treat people with liposarcoma, osteosarcoma, and Ewing / Ewing-like sarcomas.
   
   One drug like regorafenib, called pazopanib, is approved to treat some sarcomas, but is not approved to treat liposarcoma, osteosarcoma.
   
   Since we do not know if any of these types of drugs help people with liposarcoma, osteosarcoma, or Ewing/Ewing-like sarcoma, our goal in this study is to find out if regorafenib is useful for people with your type of sarcoma.

3. Study Comparing NOVOCART 3D and Microfracture Surgery for Treatment of Articular Knee Cartilage

   Rochester, Minn.

   The purpose of this research study is to gather information on the safety and effectiveness of Autologous Chondrocyte Transplantation system, Novocart® 3D, in comparison to standard microfracture treatment for injured knee.

    

    

4. A Study to Evaluate Manipulation Under Anesthesia After Bilateral Primary Total Knee Arthroplasty

   Rochester, Minn.

   The purpose of this study is to determine unique genetic profile of patients requiring MUA following bilateral pTKA via genetic sequencing, to determine outcomes of patients receiving MUA in terms of KSS, implant durability, survival free of reoperation, and to define characteristics and comorbidities of patients undergoing unilateral and bilateral MUA.

5. A Study to Evaluate Sex Disparities in Arthrogenic Muscle Inhibition

   Rochester, Minn.

   Incidence of anterior cruciate ligament (ACL) ruptures disproportionately affect female athletes at a rate 4-6 times greater than male counterparts. In addition, females have a reinjury rate 16 times that of healthy female controls and 4 times that of male ACL reconstruction (ACLR) counterparts. After ACL injury and throughout rehabilitation, a ubiquitous impairment that limits athlete progression to return to sport (RTS) is atrophy of the musculature surrounding the knee, termed arthrogenic muscle inhibition (AMI).The focus of the study is to develop an objective, reproducible, and reliable measure of neuromotor activation (directly correlated with AMI) and neuromuscular elicited muscle stiffness for both injury prevention and rehabilitation.

6. Outcome of Capsular Release for Elbow Contracture

   Rochester, Minn.

   The purpose of this study is to assess the outcome and complications of capsular release for elbow contractures.

    

7. Metrics of Osteochondral Allografts (MOCA) Registry of the Knee

   Rochester, Minn.

   The primary objective of this registry is to obtain long-term survivorship data for the use of fresh OCAs in cartilage repair and reconstruction procedures.

8. A Study of Anterior Cruciate Ligament Injury and Rehabilitation

   Rochester, Minn., Minneapolis, Minn.

   The purpose of this study is to establish arthrogenic muscle inhibition (AMI) as a neural mechanism by examining the bilateral neuromotor drive of thigh musculature from AMI progression after anterior cruciate ligament (ACL) injury. The study will also determine the inhibitory effect of aberrant proprioceptive afferents on quadriceps and hamstring motor output. Furthermore, this study will determine the efficacy of neurofeedback to induce central changes that provide peripheral benefits to muscle activation.

9. Genetic Analysis of Disorders of Fibrosis

   Rochester, Minn.

   The specific aim of this protocol is to identify microRNAs that are differentially expressed between diseased fibrotic tissue (dupuytrens disease and plantar fibromatosis) and normal fibrotic tissue.

10. A Study of Lofexidine for Rapid Opioid Tapering in Adults

    Rochester, Minn.

    The purpose of this study is to assess the effects of lofexidine on opioid tapering in adults undergoing opioid tapering prior to elective lumbar spine surgery.