1. Aug. 20, 2021

    Genetic tumor testing for more-precise treatment of glioma

    Mayo Clinic's cerebral spinal fluid biomarker tests use next-generation sequencing to evaluate mutations and rearrangements in 187 genes, for optimal tumor management.

  2. July 31, 2021

    Establishing the pulmonary oncologic toxicity clinic to care for patients with lung toxicity

    Mayo Clinic Pulmonary and Critical Care Medicine is establishing a pulmonary oncologic toxicity clinic to care for patients with lung toxicity from chemotherapy, radiation and immunotherapy.

  3. July 16, 2021

    Immune checkpoint-induced hypoparathyroidism: A case from the endocrine teaching clinics

    Immune checkpoint inhibitor (ICI) drugs have revolutionized cancer therapy. Mayo Clinic endocrinologists discuss the case of a 76-year-old male with widespread metastatic melanoma who presented with weakness, anorexia a[...]

  4. July 01, 2021

    Recent findings and future directions in non-Hodgkin's lymphoma therapy

    Immune blockade therapy isn't nearly as effective as a sole treatment for non-Hodgkin's lymphomas compared with Hodgkin's lymphoma. Mayo Clinic researchers see potential for this therapy in combination with others.

  5. June 26, 2021

    Appropriate evidence-based triage is vital to outcomes in advanced epithelial ovarian cancer

    Two studies indicate the importance of triaging patients with advanced epithelial ovarian cancer by frailty and sarcopenia status for best survival and fewer complications.

  6. June 26, 2021

    Sentinel lymph node biopsy decreases lymphedema for patients with endometrial cancer

    Unlike use of lymphadenectomy, with a 49.4% rate of lower extremity lymphedema, using sentinel lymph node biopsy to stage patients with endometrial cancer led to a 26.0% rate of this type of lymphedema.

  7. June 18, 2021

    Assessing the performance of methylated DNA markers in blood for detection of pancreatic ductal adenocarcinoma

    A blood test combining methylated DNA markers with carbohydrate antigen 19-9 detects pancreatic ductal adenocarcinoma with high accuracy.

  8. June 11, 2021

    Where we are with gastric and esophageal cancers

    A Mayo Clinic medical oncologist answers questions about diagnosis and screening and discusses treatment advances in recent years for gastric and esophageal cancers.

  9. June 04, 2021

    Groundbreaking early cancer detection test studied at Mayo Clinic introduced nationally

    Mayo Clinic today recognized the debut of a groundbreaking multi-cancer early cancer detection (MCED) test called Galleri? that can detect more than 50 types of cancers[1] through a simple blood draw. The Galleri test[...]

  10. June 03, 2021

    Mayo Clinic study provides clarity on use of anticoagulants in gastrointestinal cancers

    ROCHESTER, Minn. -- A study by Mayo Clinic researchers provides some clarity in the use of direct oral anticoagulants (DOAC), such as apixaban and rivaroxaban, to treat acute venous thromboembolism (VTE) in patients w[...]

  11. May 22, 2021

    Development of urosymphyseal fistula in posterior urethral stenosis

    Research supports that patients who develop posterior urethral stenosis and urosymphyseal fistula following salvage radiation after prostatectomy can achieve a durable restoration of quality of life.

  12. May 22, 2021

    Study assesses cost-effectiveness of pembrolizumab for treatment of bacillus Calmette-Guerin-unresponsive bladder carcinoma in situ

    Research confirms that pembrolizumab at current pricing is not cost-effective for patients with bladder cancer that has proved unresponsive to bacillus Calmette-Guerin (BCG) treatment.

  13. May 18, 2021

    New therapies offer improved quality of life for patients who need laryngectomy

    Surgical options for those who need laryngectomy to date have not satisfied all patients. An otolaryngologist at Mayo Clinic in Arizona talks about his work on alternatives: larynx transplant and 3D-printed prosthetic l[...]

  14. May 07, 2021

    Novel proton therapy technique shows promise with resistant cancer cells

    Mayo Clinic investigators believe a novel proton therapy delivery technique may bring fundamental change to radiation oncology treatment paradigms, especially for hard-to-treat cancers.

  15. May 04, 2021

    Development of new surgical procedures and predictors of outcome for patients with advanced pancreatic cancer

    Outcomes from two Mayo Clinic retrospective studies support new surgical procedures and predictors of outcome for patients with advanced pancreatic cancer.

  16. April 23, 2021

    Microscopic papillary thyroid carcinoma: elevated incidence, reasonable interventions

    Thyroid cancer rates have increased, prompted by higher screening rates and improvements. A Mayo Clinic endocrinologist discusses options of watchful waiting or treatment when thyroid nodules are small.

  17. April 17, 2021

    Young-onset esophageal adenocarcinoma: Results from a population-based study

    Mayo Clinic research examining the incidence, stage distribution and survival outcomes associated with esophageal adenocarcinoma (EAC) in a large population-based study yields some surprising results about young-onset E[...]

  18. April 15, 2021

    Elucidating a rare pituitary cancer

    A Mayo Clinic study describes the challenges of diagnosing individuals with this cancer and outlines treatment options.

  19. April 13, 2021

    Tolerability, safety and deep response found in cevostamab phase 1 trial

    A midterm analysis of a multisite phase 1 study of cevostamab for relapsed or refractory multiple myeloma (RRMM) finds the drug safe and tolerable with deep response for study participants.

  20. April 09, 2021

    Patients with HPV(+)OPSCC complete aggressive de‐escalation of adjuvant therapy without increasing risk of cancer progression

    Research compares prior de‐escalation outcomes to a contemporary cohort of patients with human papillomavirus-associated oropharyngeal squamous cell carcinoma (HPV(+)OPSCC) who met criteria for de‐escalated radiation th[...]

  21. March 16, 2021

    Mayo Clinic-developed mass spectrometry assay improves detection of monoclonal proteins, advancing outcomes in hard-to-treat diseases

    A clinical biochemist and scientific team from Mayo Clinic created a new screening and monitoring tool for monoclonal protein disorders, advancing outcomes in hard-to-treat diseases.

  22. March 13, 2021

    Ide-cel, a BCMA-directed CAR-T cell therapy, shows favorable risk-benefit profile and response

    A phase 1 study finds low incidence of severe side effects and high response rate for ide-cel, an anti-BCMA CAR-T cell therapy for relapsed or refractory multiple myeloma.

  23. March 05, 2021

    mt-sDNA test shows high specificity for colorectal cancer screening in average-risk 45- to 49-year-olds

    The multitarget stool DNA (mt-sDNA) test showed more than 95% specificity in a cross-sectional study of 45- to 49-year-old patients at average risk for colorectal cancer.

  24. March 04, 2021

    PET/MRI biomarkers guide personalized treatment for patients with pancreatic cancer

    Positron emission tomography (PET)/MRI has changed how Mayo Clinic specialists treat patients with pancreatic cancer. Mayo Clinic pioneered the use of PET/MRI to manage pancreatic cancer. Now a new study by Ananya Panda, M[...]

  25. Feb. 15, 2021

    Researchers identify gene implicated in neuroblastoma, a childhood cancer

    ROCHESTER, Minn. ? A new study by Mayo Clinic researchers has identified that a chromosome instability gene, USP24, is frequently missing in pediatric patients with neuroblastoma, an aggressive form of childhood [...]

  26. Feb. 13, 2021

    Screening strategies for prevalent esophageal adenocarcinoma may be different from those recommended for Barrett's esophagus

    Researchers find evidence that a second phenotype of esophageal adenocarcinoma is not associated with chronic gastroesophageal reflux and other Barrett's esophagus risk factors.

  27. Feb. 05, 2021

    High-risk nonmuscle invasive bladder cancer

    In a phase III clinical trial, 53% of patients with nonmuscle invasive bladder cancer (NMIBC) in the carcinoma in situ cohort had a complete response within three months of treatment.

  28. Jan. 23, 2021

    mSMART: A clear and simple guide for treating patients with multiple myeloma

    If you've ever wondered what Mayo Clinic would do to treat its multiple myeloma patients, guidelines called mSMART outline Mayo specialists' current treatment approach.

  29. Jan. 19, 2021

    Adrenal masses require full investigation at the time of discovery

    Researchers using Rochester Epidemiology Project data have identified a population-based proportion of malignant tumors and other information helpful when discussing management with a patient newly diagnosed with an adr[...]

  30. Jan. 16, 2021

    New minimally invasive vascularized lymph node transfer for lymphedema

    Single-port robotic omental harvest for the surgical treatment of lymphedema using a free lymph node transfer minimizes donor site morbidity and alleviates debilitating symptoms of lymphedema.

  31. Jan. 08, 2021

    Determining the best treatment course for patients with multiple myeloma

    A long-term strategy for management of multiple myeloma should include a risk-stratified approach as well as selecting the ideal combinations and sequencing the hematologist can determine for each patient's disease.

  32. Dec. 29, 2020

    Pemigatinib trial seeks to build on targeted advances in cholangiocarcinoma

    Tanios S. Bekaii-Saab, M.D., discusses the explosion of research leading to the approval of pemigatinib for patients with unresectable, previously treated advanced or metastatic cholangiocarcinoma with FGFR2 fusion or r[...]

  33. Dec. 22, 2020

    Making up for lost time in GI cancers

    Tanios S. Bekaii-Saab, M.D., discusses how the field of gastrointestinal (GI) cancers is gaining ground with regard to the development of targeted and immunotherapy agents.

  34. Dec. 18, 2020

    Broad-based testing increases detection of inherited germline variants in patients with cancer

    Universal germline genetic testing found that 13.3% of study participants harbored a pathogenic germline variant — 48% of which would not have been detected using standard guidelines.

  35. Dec. 17, 2020

    Pelvic exenteration: Radical but positive for carefully selected patients with pelvic cancer

    A Mayo Clinic gynecologic surgeon discusses how pelvic exenteration, though radical, can benefit carefully selected patients and how complications can be predicted.

  36. Nov. 20, 2020

    Improving quality of life for patients living with oropharyngeal cancer

    A Mayo Clinic study supports that compared with intensity-modulated radiation therapy, proton beam therapy is better tolerated by patients who've had expert transoral surgical resection of oropharyngeal cancer.

  37. Nov. 20, 2020

    Therapeutic sequencing improves outcomes for patients with progressive mCRPC

    Researchers investigated the long-term oncologic outcomes of three chemotherapy regimens in patients who had previously experienced disease progression after treatment with a novel androgen receptor inhibitor.

  38. Nov. 02, 2020

    Mayo Clinic study finds 1 in 8 patients with cancer harbor inherited genetic mutations

    The Interrogating Cancer Etiology Using Proactive Genetic Testing (INTERCEPT) study represents the largest known multicenter study of universal testing of patients with cancer.

  39. Oct. 30, 2020

    Breast radiotherapy team at Mayo Clinic adopts shortened courses to spare normal tissue

    Mayo Clinic helps patients with breast cancer by sparing normal tissue and reducing treatment time via newly adopted practice guidelines embracing short-course radiotherapy as a standard of care.

  40. Oct. 09, 2020

    Consensus reached on initial treatment of acute graft-versus-host disease in patients who receive bone marrow transplant; nothing definitive yet for secondary treatment

    There are now two approved second line therapies for treatment of steroid-refractory GVHD ― one for acute GVHD and one for chronic GVHD.

  41. Sept. 15, 2020

    New research indicates maintenance bacillus Calmette-Guerin is not cost-effective for all patients with intermediate- and high-risk nonmuscle invasive bladder cancer

    New research supports prioritizing bacillus Calmette-Guerin (BCG) for induction therapy during shortages and reserving maintenance BCG for patients at the highest risk of progression.

  42. Sept. 04, 2020

    Incidence and characteristics of therapy-related myeloid neoplasms after peptide receptor radionuclide therapy in patients with neuroendocrine tumors

    Drs. Sonbol and Halfdanarson share findings of their systematic review on the frequency of therapy-related myeloid neoplasm (t-MN) in patients with neuroendocrine tumors after PRRT.

  43. Aug. 28, 2020

    Identification of actionable alterations in colorectal cancer are leading to the development of novel treatment strategies

    Daniel H. Ahn, D.O., talks about the latest advancements and research in colorectal cancer treatment.

  44. Aug. 21, 2020

    Cardio-oncology — A marriage of cardiology & oncology

    With more cancer drug options and increased treatment success, patients with cancer are surviving in record numbers. To address negative side effects of therapies on the heart and vascular function, Mayo Clinic establis[...]

  45. Aug. 15, 2020

    Comparing modalities for detecting dysplasia in patients with IBD

    A one-year cross-sectional IBD surveillance colonoscopy cohort compares high-definition white light endoscopy and chromoendoscopy.

  46. Aug. 14, 2020

    This is not your mother's breast clinic

    Breast Clinic specialists discuss how the complexity of breast cancer treatment requires integration of multiple specialties to provide the expert care, seamless coordination and patient experience for which Mayo Clinic[...]

  47. Aug. 14, 2020

    Patients receiving lutetium Lu 177 dotatate radiation therapy may experience travel delays

    Radiation used in peptide receptor radionuclide therapy could be detected by sensitive radiation detectors at U.S. ports of entry, including international airports and border crossings.

  48. Aug. 14, 2020

    Glioblastoma: Seeking personalized care through radiomics

    Mayo Clinic is using radiomics to learn more about individuals' responses to glioblastoma treatment. Tumor volume can affect an individual's response to chemotherapy. Differences in the molecular mechanisms of tumors in[...]

  49. Aug. 08, 2020

    Second-line treatment options for hepatocellular carcinoma

    Tanios S. Bekaii-Saab, M.D., F.A.C.P., discusses the rapidly changing hepatocellular carcinoma treatment landscape and shares how he navigates first-line and second-line treatment options for these patients.

  50. Aug. 04, 2020

    Pediatric brain tumors: Rapid and focused care

    Patients referred to Mayo Clinic for pediatric brain tumor can often be seen the next day. A team of specialists works together, drawing on Mayo's broad expertise in neuro-oncology.

  51. Aug. 02, 2020

    Herd immunity, antibodies & COVID-19 / bile duct cancer / peripheral artery disease

    On the Mayo Clinic Radio program, Dr. S. Vincent Rajkumar, a Mayo Clinic hematologist and researcher, discusses herd immunity, antibodies and how the body works to fight off disease. Dr. Bret Petersen, a Mayo Cli[...]

  52. July 01, 2020

    Oncology centers examine the aftermath of COVID-19 on clinical trials with Steven R. Alberts, M.D.

    Medical oncologist and interim chair of the Mayo Clinic Cancer Center, Dr. Alberts provides his perspective on how COVID-19 has affected clinical trials for cancer and what patients should know about receiving care duri[...]

  53. June 27, 2020

    Glioblastoma extracellular vesicles: Targeting the ill effects, using the good

    The mechanisms by which glioblastoma-derived extracellular vesicles promote tumor growth appear to be more complicated than previously thought. Mayo Clinic is working to exploit certain factors of extracellular vesicles[...]

  54. June 16, 2020

    Mayo Clinic, NASA team up to test AI algorithm on colorectal cancer

    A Center for Individualized Medicine algorithm shows potential in detecting spatio-temporal patterns of colorectal cancer progression from tumor snapshots to predict the cancer's evolutionary trajectory.

  55. June 13, 2020

    New approaches to immunotherapy for glioblastoma

    Mayo Clinic is advancing new applications of immunotherapy for glioblastoma, with a focus on more-potent and combination therapies for optimal effectiveness.

  56. May 13, 2020

    Esophageal cancer treatment amid COVID-19: Q&A with Shanda Blackmon, M.D., M.P.H.

    Thoracic surgeon Dr. Blackmon provides her perspective on how COVID-19 has affected esophageal cancer treatment and what patients should know about receiving care during this pandemic.

  57. May 09, 2020

    How COVID-19 could impact future practice: Q and A with Tanios S. Bekaii-Saab, M.D., F.A.C.P.

    Tanios S. Bekaii-Saab, M.D., FACP, medical oncologist at Mayo Clinic in Phoenix, Arizona, answers questions on how COVID-19 could impact the future practice of medicine.

  58. May 08, 2020

    Lung cancer care during COVID-19: Q&A with Shanda Blackmon, M.D., M.P.H.

    Thoracic surgeon Dr. Blackmon answers questions on how COVID-19 has affected lung cancer treatment, what patients should know about risks, and care and referral considerations.

  59. May 02, 2020

    Patient safety and care delivery remain the focus at Mayo Clinic Cancer Center: A special message from Robert R. McWilliams, M.D., practice chair, Mayo Clinic Cancer Center

    Continuing to provide lifesaving cancer treatment is a priority for Mayo Clinic. Following our primary value, "The needs of the patient come first," patients have continued to safely receive care for cancer at our locat[...]

  60. April 17, 2020

    Steroid profiling in the diagnosis of malignant adrenal masses: Cases from the endocrine teaching clinics

    Endocrinologists Shobana Athimulam, M.B.B.S., and Irina Bancos, M.D., discuss the diagnoses and next steps in management of two patients with malignant adrenal tumors.

  61. March 20, 2020

    Alternative, innovative method of delivering chemotherapy shows promising results, retrospective review says

    Hyperthermic intraperitoneal chemotherapy (HIPEC) has been shown to decrease the risk of recurrence and improve the survival of patients with peritoneal-based malignancies, with minimal side effects.

  62. March 20, 2020

    Complex gynecological surgery for recurrent cancer: Navigating challenges when communicating with patients and their families

    Pelvic exenteration is used to treat cancer in the pelvic organs that has recurred after other treatment. Providers' empathy and understanding is vital to successful patient-centered care.

  63. March 02, 2020

    Immune cells may improve accuracy of predicting survival in colorectal cancer

    ROCHESTER, Minn. -- The density of immune cells, called tumor infiltrating lymphocytes, when combined with analysis of tumor budding may serve as a method to more accurately predict survival in patients with stag[...]

  64. March 02, 2020

    Mayo researchers recommend all women with breast cancer diagnosis under age 66 be offered genetic testing

    ROCHESTER, Minn. -- A study by researchers at Mayo Clinic published this week in the Journal of Clinical Oncology suggests that all women with a breast cancer diagnosis under the age of 66 be offered germline genetic [...]

  65. Feb. 28, 2020

    Enterprisewide expertise for spinal oncology care

    Mayo's spinal oncology specialists may employ proton beam therapy, carbon fiber implants or surgical alternatives ― such as decompression, stabilization, ablation technologies or cement augmentation ― to meet each patie[...]

  66. Feb. 22, 2020

    Percutaneous biopsy of suspicious upper tract lesions a safe diagnostic strategy

    A retrospective review of patients who received percutaneous image-guided core-needle biopsy for diagnosis of upper tact urothelial carcinoma supports that the process is safe and well tolerated by those patients.

  67. Feb. 22, 2020

    Optimal sequencing of commonly used medications for treatment of metastatic castration-resistant prostate cancer

    Research supports the use of docetaxel before enzalutamide or abiraterone as the primary first line therapy for metastatic castration-resistant prostate cancer.

  68. Feb. 14, 2020

    Detection of esophageal cancer via assay of novel methylated DNA markers in plasma

    In the largest plasma-based pilot of esophageal cancer biomarkers to date, Mayo Clinic researchers identified five methylated DNA markers (MDMs) that achieved high discrimination for cancer.

  69. Feb. 14, 2020

    Update on hereditary gastrointestinal cancers: Lynch syndrome and familial adenomatous polyposis syndromes

    A primer on Lynch syndrome, familial adenomatous polyposis (FAP) and attenuated FAP provides clinicians with tools to understand the genetic bases of these conditions and appropriate diagnosis and management.

  70. Feb. 14, 2020

    Prepless colon capsule technology: New research examines this less invasive approach to colorectal cancer screening

    Mayo gastroenterologists are collaborating in the first U.S. study evaluating the safety and compliance of a prepless capsule imaging system for colorectal cancer (CRC) screening.

  71. Feb. 14, 2020

    Role of AI in detection and management of colorectal polyps and cancer

    Up to 25% of polyps can be missed during colonoscopy, due to factors such as withdrawal time, preparation quality and the endoscopist's ability to recognize flat polyps.

  72. Feb. 07, 2020

    Mayo researchers discover way to prime cancer tumors for immunotherapy

    ROCHESTER, Minn. ? A cancer tumor's ability to mutate allows it to escape from chemotherapy and other attempts to kill it. So, encouraging mutations would not be a logical path for cancer researchers. Yet a Mayo Clinic tea[...]

  73. Jan. 06, 2020

    Out of the shadows: Understanding endocrine cancers

    Mayo Clinic's Endocrine Malignancies Disease Group focuses on patients with less-common endocrine cancers, leading to an optimized approach to thyroid nodules and improved overall survival in anaplastic thyroid cancer.

  74. Dec. 17, 2019

    Many younger patients with stomach cancer have a distinct disease, Mayo research discovers

    ROCHESTER, Minn. -- Many people under 60 who develop stomach cancer have a "genetically and clinically distinct" disease, new Mayo Clinic research has discovered. Compared to stomach cancer in older adults, this new, early[...]

  75. Dec. 16, 2019

    Mayo Clinic researchers look at post menopause as key factor in endometrial cancer

    ROCHESTER, Minn. -- Endometrial cancer is the most common gynecological malignancy in the U.S. and the fourth most common cancer among women. In addition, endometrial cancer incidence rates are on the rise in the western w[...]

  76. Dec. 13, 2019

    New therapy improving lives of patients with neuroendocrine tumors

    For some patients neuroendocrine tumors lead to diarrhea or pain, while others will have no symptoms and the tumors are only discovered during an imaging exam for another issue. But now a new treatment option is available [...]

  77. Dec. 10, 2019

    Tweaking protein may improve colorectal cancer outcomes

    Mayo Clinic researchers tweak a key protein to boost effectiveness of chemotherapy in colorectal cancer: Mayo Clinic Forefront cancer magazine.

  78. Dec. 10, 2019

    Researchers discover distinct pathways in lung adenocarcinoma

    Discovery of distinct pathways in lung adenocarcinoma may help improve targeted cancer therapies: Mayo Clinic Forefront cancer magazine.

  79. Dec. 10, 2019

    Mayo Clinic calls out need for aggressive glioblastoma treatment

    Aggressive cellular therapy, new drugs, surgery & clinical trials needed for glioblastoma brain tumor survival: Mayo Clinic Forefront cancer magazine.

  80. Dec. 10, 2019

    Scientists find autoimmune disease related to testicular cancer

    Scientists urge screening for paraneoplastic encephalitis autoimmune disease in patients with testicular cancer: Mayo Clinic Forefront cancer magazine.

  81. Oct. 26, 2019

    One of the largest male breast cancer studies to date illuminates state of treatment, prognosis and health disparities

    Mayo investigators have identified unique practice patterns and prognosis factors in male breast cancer, and associated health disparities. Studies indicate the incidence of breast cancer in males may be on the rise.

  82. Oct. 22, 2019

    Panel of methylated DNA markers provides improved accuracy in detecting advanced neoplasia and other lesions that may require resection

    Researchers identified and validated a panel of DNA methylation markers that can detect advanced neoplasia and help determine which cysts require surgery.

  83. Oct. 22, 2019

    Evaluating the safety and diagnostic accuracy of endoscopic fine-needle aspiration for detection of extravascular migratory metastases in the pancreas

    In a retrospective review, researchers demonstrated that cytology analysis of pancreatic samples collected by endoscopic ultrasound fine-needle aspiration (EUS-FNA) can detect extravascular migratory metastases often mi[...]

  84. Oct. 22, 2019

    Assessing the timeline, location and patterns of recurrence in patients achieving complete remission after radiofrequency ablation

    Researchers assessed the timeline, location and patterns of recurrence in patients who achieved remission after radiofrequency ablation in a multicenter cohort study.

  85. Sept. 24, 2019

    Soft tissue sarcoma: Technology and expertise to improve care

    Wound-healing complications are common after surgical resection for soft tissue sarcoma. Intraoperative fluorescence angiography assesses blood flow and tissue perfusion, allowing for the surgical removal of nonviable t[...]

  86. Sept. 11, 2019

    Infographic: Scalp cooling therapy

    Learn more about chemotherapy and hair loss. More healthtip infographics:

  87. Aug. 27, 2019

    New analysis shows radical prostatectomy to be cost-effective management of prostate cancer

    A cost-effectiveness study indicates that the ProtecT trial actually supports the upfront treatment of more-aggressive prostate cancers and the surveillance of less aggressive prostate cancers.

  88. Aug. 01, 2019

    Blocking YAP May Aid in Treating Brain Cancer

    Researchers found that a drug known to inhibit yes-associated protein can reduce the growth of highly aggressive glioblastoma cells in animal and cell models and make glioblastoma cells more susceptible to radiation.

  89. June 21, 2019

    New data indicate percutaneous ablation may be an appropriate option for certain patients with renal masses

    A review of patients treated with partial nephrectomy, percutaneous radiofrequency ablation or percutaneous cryoablation for small renal masses found no clinical or statistical difference in five-year outcomes.

  90. June 18, 2019

    Study helps clarify role of T cells in follicular lymphoma

    Mayo Clinic researchers find that costimulatory receptors on T cells may be key in treating follicular lymphoma: Mayo Clinic Forefront cancer magazine.

  91. April 19, 2019

    Axi-cel treatment for B-cell lymphoma provides real-world outcomes comparable to ZUMA-1 trial data

    In a study of axicabtagene ciloleucel (axi-cel) CAR-T cell therapy for relapsed or refractory aggressive B-cell lymphoma, 30-day responses were comparable to the ZUMA-1 trial's best responses.

  92. March 20, 2019

    Researchers pursue new strategies for CAR-T cell therapy

    Mayo Clinic researchers find ways to reduce toxicity and improve response rates in CAR-T cell therapy: Mayo Clinic Forefront cancer magazine.

  93. Dec. 21, 2018

    Beating the beast: Mayo Clinic's pediatric urologists and their sarcoma team's mission to cure rhabdomyosarcoma

    Mayo pediatric radiologists construct 3D, color-coded models of the tumor and surrounding structures to assess the best potential therapies for each child and assist the surgical team with preoperative planning and refe[...]

  94. Dec. 11, 2018

    Team IDs genes that boost risk of triple-negative breast cancer

    Research team led by Mayo Clinic IDs genes that boost the risk of triple-negative breast cancer: Mayo Clinic Forefront cancer magazine.

  95. Sept. 01, 2018

    Onco-Epilepsy: More Than Tumor and Seizures

    Research published in Mayo Clinic Proceedings indicates that onco-epilepsy, a combined approach to brain tumor management, may extend survival and improve patients' quality of life.

  96. June 19, 2018

    Predicting which colon polyps might transform to cancer

    Mayo Clinic researchers move closer to understanding why certain colon polyps transform to colon cancer: Mayo Clinic Forefront cancer magazine.

  97. April 14, 2018

    Laparoscopic gastrectomy for gastric cancer

    The minimally invasive procedure offers faster recovery, less blood loss and pain, and a return to eating and normal bowel function more quickly. The hospital stay is shorter and the patient is less likely to need a fee[...]

  98. Feb. 27, 2018

    Inherited cancers clinic seeks to advance understanding, diagnosis and management of hereditary colorectal cancers

    Use of a simple questionnaire of personal and family history of cancer in outpatient settings helps improve the identification of high-risk patients and families, detect cancers earlier, and formulate more-effective ind[...]

  99. Feb. 20, 2018

    Targeted DNA next-generation sequencing aids the molecular assessment of pancreatic neuroendocrine tumors

    A recent Mayo Clinic study demonstrated that endoscopic ultrasound-acquired cytology-based tumor genotyping can reveal a spectrum of genetic variants, which may help guide biomarker-driven, individualized, targeted trea[...]

  100. Feb. 15, 2018

    Cytoreductive surgery and HIPEC offers effective treatment for selected patients with peritoneal carcinomatosis

    A retrospective study of intermediate-term outcomes for patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) indicates the treatment was most successful for patients with res[...]

  101. Dec. 05, 2017

    Mayo Clinic researchers show how neuroblastoma spreads

    Mayo Clinic researchers show how neuroblastoma spreads: Mayo Clinic Forefront.

  102. Nov. 22, 2017

    The Fish Farm

    Zebrafish have become the model of choice in many medical laboratories. They breed more prolifically and hold more animals per research footprint compared with other vertebrates, and can be very resource-friendly.

  103. Nov. 01, 2017

    Starving Cancer

    Mayo researchers are studying genes that are highly expressed in cancerous tissue but not in normal tissue and examining the cause and effect of fatty acid synthase in the cancer cell to identify a process to starve can[...]

  104. Sept. 19, 2017

    Genetic test accurately detects early pancreatic cancer

    Biomarkers in pancreatic cyst fluid may be key to discovering early cancer or advanced precancerous lesions: Mayo Clinic Forefront.

  105. July 14, 2017

    Mayo Clinic streamlines hepatocellular carcinoma treatment

    Mayo Clinic's efficient, coordinated care leads to superior outcomes in liver cancer and liver transplantation.

  106. June 13, 2017

    Meet the investigator: Kristin R. Swanson, Ph.D.

    Kristin R. Swanson, Ph.D., of Mayo Clinic, discusses her brain cancer research: Mayo Clinic Forefront.

  107. March 24, 2017

    Cleaning Up Cancer

    Researchers use a variety of approaches to address two big challenges: strengthen the immune response to recognize and attack cancer; and keep the immune system on high alert, even as cancer cells struggle to reduce the[...]

  108. Feb. 25, 2017

    Innovative approaches improve limb salvage in pediatric patients with cancer

    Advances including adjuvant chemotherapy regimens, improved imaging and custom implants have improved the five-year survival rate for local pediatric bone cancers to 60 to 80 percent.

  109. Feb. 22, 2017

    Strategy to prevent chemotherapy-induced neuropathy

    Mesenchymal stem cells act as therapy for nervous system diseases by carrying extracellular products across the blood-brain barrier in patients with amyotrophic lateral sclerosis. The stem cells may also be used to deli[...]

  110. Dec. 18, 2016

    Stereotactic radiosurgery is best for some brain tumors

    Mayo Clinic Forefront magazine: Shift in practice may reserve whole-brain radiation for patients with extensive disease.

  111. Nov. 18, 2016

    Fertility preservation: Efforts to improve quality of life in children facing gonadotoxic therapy

    Recent advances in reproductive endocrinology allow cryopreservation of prepubertal boys' testicular tissue and girls' ovarian tissue before they begin cancer therapy known to impact fertility adversely.

  112. Nov. 18, 2016

    Finding new treatments for high-grade pediatric brain tumors

    Brain and central nervous system tumors now represent the most common cause of cancer-related death in children. New information about the molecular diversity of these tumors points the way toward targeted therapies tai[...]

  113. Sept. 26, 2016

    Battling Brain Cancers Through Genomics

    A study of the classification of genetic alterations common to gliomas indicates that molecular methods can do a better job than current methods of predicting which specific treatment course is necessary for each indivi[...]

  114. July 16, 2016

    Multidisciplinary treatment in rectal cancer

    Despite improvements in preoperative tumor staging and outcomes, evaluation and management of locally advanced rectal cancer presents ongoing challenges for physicians and patients, highlighting the need for multidiscip[...]

  115. July 15, 2016

    Stool DNA has potential for multiple cancer screenings

    Methylated DNA may not only provide an affordable, noninvasive method for pancreatic cancer screening but also represent a first step toward a universal cancer screening test.

  116. July 15, 2016

    Aspirin a potential chemopreventive agent for cholangiocarcinoma

    Building on a long history of aspirin research, Mayo investigators find an association between aspirin use and a significant reduction in the three subtypes of cholangiocarcinoma.

  117. April 29, 2016

    Glioma: New classification and the search for treatment

    Researchers have defined five biologically distinct tumor groups that may suggest pathways for developing more-precise treatments for patients with gliomas.

  118. March 19, 2016

    Proton beam therapy reduces toxicity, increases survival in some GI cancers

    Proton beam therapy can create dose distributions that conform to tumor targets with significant sparing of normal tissue. This may make it a superior modality for some gastrointestinal cancers.

  119. Jan. 19, 2016

    Rethinking comparative effectiveness research

    IBD effectiveness trials are needed to foster evidence-based changes in clinical practice, but remain challenging to fund and recruit. An IBD specialist says investigators must become more creative in their approach to [...]

  120. Dec. 03, 2014

    Cologuard primed to change landscape of CRC screening

    Recently approved by the FDA and simultaneously covered by Medicare, Cologuard is a noninvasive stool DNA screening test for colorectal cancer with demonstrated 92 percent sensitivity in detecting cancer stages I-IV and[...]

  121. Sept. 10, 2014

    Genetic abnormalities in ALK-negative ALCLs may guide therapy

    A new study finds genetic heterogeneity among ALK-negative anaplastic large cell lymphomas (ALCLs) and strikingly different clinical outcomes among patients with different genetic subtypes.

  122. March 05, 2014

    40 years of addiction treatment at Mayo Clinic

    40 years of addiction treatment - In keeping with its tradition of groundbreaking work in addictive disorders treatment, Mayo has established the Samuel C. Johnson Genomics of Addictions Research Program, with the long-[...]

  123. Sept. 05, 2013

    Cancer immunotherapy eradicates tumors from within

    Cancer immunotherapy cures tumor-burdened mice - Researchers used human DNA from melanoma cells delivered through the vector vesicular stomatitis virus to eradicate cancerous tumors in mice. Success is associated with t[...]

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