Precautions
Drug information provided by: Merative, Micromedex®
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.
Do not use this medicine if you are also using cyclophosphamide or medicine to treat infections (eg, clarithromycin, itraconazole, ketoconazole).
Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant during treatment. If you think you have become pregnant while using the medicine, tell your doctor right away.
This medicine may increase your risk for certain cancers, including lymphoma or skin cancer. Avoid sun exposure. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds. Talk to your doctor if you have concerns about this risk.
Your body's ability to fight infection may be reduced while you are being treated with voclosporin. It is very important that you call your doctor at the first signs of any infection. Check with your doctor right away if you or your child have fever, chills, cough or hoarseness, flu-like symptoms, lower back or side pain, painful or difficult urination, or unusual tiredness or weakness.
This medicine may cause serious kidney problems. Check with your doctor right away if you have blood in your urine, change in frequency of urination or amount of urine, difficulty in breathing, drowsiness, increased thirst, loss of appetite, nausea or vomiting, swelling of the feet or lower legs, or weakness.
This medicine may cause high blood pressure. Check with your doctor right away if you have blurred vision, dizziness, headache, nervousness, pounding in the ears, or slow or fast heartbeat.
This medicine may cause serious nervous system problems (eg, posterior reversible encephalopathy syndrome). Check with your doctor right away if you have blurred or double vision, difficulty in walking, headache, jaw pain, numbness or tingling in the fingers and toes, pain in the fingers and toes, pain the testicles, or weakness.
Tell your doctor right away if you have confusion, difficult breathing, irregular heartbeat, nausea or vomiting, nervousness, numbness or tingling in the hands, feet, or lips, stomach pain, or weakness or heaviness of the legs. These may be symptoms of hyperkalemia.
This medicine may cause heart rhythm problems (eg, QT prolongation). Check with your doctor right away if you have chest pain or discomfort, fainting, irregular or slow heart rate, or trouble breathing.
While you are being treated with voclosporin, and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor's approval. Voclosporin may lower your body's resistance and there is a chance you might get the infection the immunization is meant to prevent. In addition, other persons living in your household should not take or should not have taken oral polio vaccine within the last several months since there is a chance they could pass the polio virus on to you. Also, avoid other persons who have taken oral polio vaccine. Do not get close to them and do not stay in the same room with them for very long. If you cannot take these precautions, you should consider wearing a protective face mask that covers the nose and mouth.
This medicine may cause a blood disorder called pure red cell aplasia. Check with your doctor right away if you have fever, sore throat, pale skin, unusual bleeding or bruising, or unusual tiredness or weakness.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Portions of this document last updated: April 01, 2024
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