Proper Use

Medicines used to treat cancer are very strong and can have many side effects. Before using this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

This medicine comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Do not substitute the two dosage forms of this medicine. Lynparza® capsules and tablets are not the same and they contain different doses.

Swallow the capsules and tablets whole. Do not crush, break, chew, open, or dissolve them. Do not take the capsules if they look damaged or have a leakage.

You may take this medicine with or without food.

Do not eat grapefruit or Seville oranges, or drink grapefruit or Seville orange juice while you are using this medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (capsules):
    • For advanced ovarian cancer:
      • Adults—400 milligrams (mg) (eight 50 mg capsules) 2 times a day. Each dose should be taken 12 hours apart. Your doctor may adjust your dose as needed.
      • Children—Use and dose must be determined by your doctor.
  • For oral dosage form (tablets):
    • For breast cancer, ovarian cancer, fallopian tube cancer, or primary peritoneal cancer:
      • Adults—300 milligrams (mg) (two 150 mg tablets) 2 times a day. Each dose should be taken 12 hours apart. Your doctor may adjust your dose as needed or tolerated. However, dose is usually not more than 600 mg (four 150 mg tablets) per day.
      • Children—Use and dose must be determined by your doctor.
    • For maintenance treatment of advanced ovarian cancer:
      • Adults—300 milligrams (mg) (two 150 mg tablets) 2 times a day for up to 2 years. Each dose should be taken 12 hours apart. Your doctor may adjust your dose as needed or tolerated. However, dose is usually not more than 600 mg (four 150 mg tablets) per day.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep the tablets in their original container.