Cuidado de la columna vertebral

A continuación se enumeran ensayos clínicos actuales.

Filtrar esta lista de estudios según la ubicación, el estado del estudio y más.

1. Use of Tamsulosin to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

   Rochester, Minn.

   Postoperative urinary retention is a frequent complication of spinal surgeries and impacts a large portion of this population which results in increased morbidity as a result of increased number of catheterizations, urinary tract infections (UTIs) and prolonged hospital stays. With the addition of Tamsulosin, the investigators would anticipate a reduction in the incidence and duration of postoperative urinary retention and therefore a reduction in morbidity related to treatment of urinary retention as well as shortened hospital stays.

2. A Study to Implement a Patient-Centered Pain Plan and Standardized Preoperative Pain Education for Patients Undergoing Lumbar Procedures

   Mankato, Minn.

   The purpose of this study is to develop a patient-centered pain plan and standardized preoperative pain education for patients undergoing lumbar procedures to increase postoperative pain control and patient satisfaction.

3. Awake vs asleep spine surgery

   Jacksonville, Fla.

   Patients undergoing spine lumbar surgery will be asked to perform short exams/questionnaires aimed at determining cognitive function, quality of life, health outcomes twice post surgery with a baseline performance prior to surgery.

4. Spinal Cord Injury and Dysfunction Registry: Acute Injury Through Life Long Care

   Rochester, Minn.

   The purpose of this project is to create and implement a Mayo Clinic spinal cord injury registry that allows team members to collect, sort and analyze patient and program information from acute spinal cord injury through lifelong follow-up.  The data will be used both clinically (for program assessment and federally required reporting) and individual research projects (e.g., patient outcomes).

5. A Registry for the Research of Primary Tumors of the Spine

   Rochester, Minn.

   The purpose of this registry is to collect clinical, diagnostic, and therapeutic data specific for primary spinal column tumor patients, and evaluate it to understand the predictive factors which influence survival, local recurrence, adverse events, perioperative morbidity, and health related quality of life.

6. Human Blood and Tissues Repository for Neuroscience Research

   Jacksonville, Fla.

   The purpose of this study is to collect adult human blood, cerebrospinal fluid, brain, and spine tissues/fluids at time of surgery in order to conduct future studies of the cellular mechanisms of tissue invasion utilized by brain and spine tumors of the central nervous system (CNS).

7. A Study of Lofexidine for Rapid Opioid Tapering in Adults

   Rochester, Minn.

   The purpose of this study is to assess the effects of lofexidine on opioid tapering in adults undergoing opioid tapering prior to elective lumbar spine surgery. 

8. Riluzole in Spinal Cord Injury Study

   Rochester, Minn.

   The aim of this study is to evaluate efficacy and safety of riluzole in the treatment of patients with acute SCI. The primary objective is to evaluate the superiority of riluzole, at a dose of 2 x 100 mg the first 24 hours followed by 2 x 50 mg for the following 13 days after injury, as compared to placebo, in change between 180 days and baseline in motor outcomes as measured by International Standards for Neurological Classification of Spinal Cord Injury Examination (ISNCSCI) Motor Score, in patients with acute traumatic SCI, presenting to the hospital less than 12 hours after injury. Secondary objectives are to evaluate the effects of riluzole on overall neurologic recovery, sensory recovery, functional outcomes, quality of life outcomes, health utilities, mortality, and adverse events. The working hypothesis is that the riluzole treated subjects will experience superior motor, sensory, functional, and quality of life outcomes as compared to those receiving placebo, with an acceptable safety profile.

9. A Study to Establish an Enterprise Neurosurgery Biobank

   Rochester, Minn.

   The purpose of this study is to expand biobanking to neurosurgical disorders where similar protocols do not exist in the institution (e.g., neurovascular disease) and complement existing biobanking protocols where they do exist (e.g., neuro-oncology, skull base tumors, degenerative spine). 

10. A Study of the Effect of Treatment on Activity and Muscle Function in Pediatric Patients with Scoliosis

    Rochester, Minn.

    This study will explore the relationship between skeletal muscle and physical activity in scoliosis patients to provide insight into both the etiology of scoliosis and possible ways to mitigate the potential harm of treatment.