Ensayos clínicos Solicite una Consulta en Mayo Clinic Médicos por sede y especialidadInvestigación Jan. 30, 2021 Comparte en: FacebookTwitter A continuación se enumeran ensayos clínicos actuales.31 estudios en Cuidados intensivos (estudios abiertos únicamente). Filtrar esta lista de estudios según la ubicación, el estado del estudio y más. A Study to Evaluate Convalescent Plasma to Stem Coronavirus Scottsdale/Phoenix, Ariz. The purpose of this study is to assess the effectiveness and safety of Human coronavirus immune plasma (HCIP) to reduce the risk of hospitalization or death, the duration of symptoms and duration of nasopharyngeal or oropharyngeal viral shedding. Real Time Detection of Electrophysiologic Disturbances Following Subdural Hematoma Evacuation Rochester, Minn. The purpose of this study is to detect and characterizer electrophysiologic disturbances (such as local field potentials) in patients with underrecognized cause of coma, focal deficits and prolonged encephalopathy following subdural hematoma (SDH) evacuation. COVID-19 Remote Monitoring Jacksonville, Fla. As a part of the COVID-19 pandemic, Mayo Clinic Florida is utilizing remote monitoring technology to monitor non-ICU patients in order to identify patients who will need the ICU and prevent crashing patients on the floor. MCF is using approved InTouch video and Biofourmis remote vital sign monitoring technology, both used by Mayo Clinic in other capacities. This study will not be a study of the efficacy or the accuracy of these devices as they are already incorporated as standard of practice. This study will assess the reduction of on floor crashing patients, quality of care, and satisfaction of providers by using this technology. COVID-19 and Acute Renal Failure Jacksonville, Fla., Scottsdale/Phoenix, Ariz., Rochester, Minn. The primary purpose of this study is to examine 1-year survival and rate of secondary infections in COVID-19 patients with and without acute kidney injury (AKI). A Study to Evaluate Oxygen Supplementation Duration to Assess Resolution of Acute Hypoxic Respiratory Failure Rochester, Minn. The purpose of this study is to assess the feasibility, reliability and validity of oxygen supplementation duration as an intermediate outcome of resolution of acute hypoxic respiratory failure from all cause in comparison with PaO2/FiO2, SaO2/FiO2 ratio, and lung injury score trajectories in critically ill patients with acute respiratory failure. Study to Compare Electrical and Ultrasonographic Evaluation of the Phrenic Nerve-Diaphragm Neuromuscular Junction (NMJ) Function Jacksonville, Fla. The purpose of this study is to ensure technical success in the treatment of assessing diaphragmatic neuromuscular junction (NMJ) function of the diaphragm in normal patients. A Study to Detect Non-convulsive Seizures with Single-channel Electroencephalogram (EEG) Rochester, Minn. The purpose of this study is to assess how accurately a portable single-channel EEG device (Epilog™ by Epitel) detects generalized non-convulsive seizures, and to determine the feasibility of use of this device in an acute setting such as the Emergency Department (ED). Development of Potential COVID-19 Vaccine and Serological Assay Rochester, Minn. Our group has explored the use of genomic RNA/phage display libraries derived from primary human malignant melanoma cells as a means of identifying antibody detectable targets on cancer cells (cancer vaccines or antibody guided therapeutics). In this approach, we isolate and affinity-column immobilize the IgG fraction from patient serum before and after immune therapy for melanoma, and expose the immobilized antibodies to bacteriophage expressing approximately 2x109 overlapping cDNA sequences of paired (same patient derived plasma and cancer cells) melanoma genomic RNA. Phage, expressing melanoma cDNA express the proteins/peptides on their capsid are “recognized” by the immobilized antibodies are retained in the column, and subsequently eluted for DNA sequencing. Comparison of the DNA profiles of the eluted phage using pre-immunotherapy and post-immunotherapy patient sera will reveal emergence of new antibodies (post-immunotherapy gain of antibodies) against proteins of potential interest for melanoma targeting. In the current proposal, we hypothesize that reacting COVID serum from patients that have recovered from COVID infection and compare to non-infected self-serum (if available) and control healthy volunteer serum (available in our lab) may identify protein targets that have developed as a result of the COVID infection and could be useful in the development of a COVID vaccine as well as a serologic test for anti-COVID immunity. A Study to Evaluate the Efficacy and Safety of Colchicine on Coronavirus SARS-CoV2 Positive Adults Jacksonville, Fla., Scottsdale/Phoenix, Ariz., Rochester, Minn. This is a phase 3, multi-center, randomized, double-blind, placebo-controlled multicenter study to evaluate the efficacy and safety of colchicine in adult patients diagnosed with COVID-19 infection and have at least one high-risk criterion. Approximately 6000 subjects meeting all inclusion and no exclusion criteria will be randomized to receive either colchicine or placebo tablets for 30 days. Training of Physicians in Critical Care Ultrasonography (CCUS) Rochester, Minn. The purpose of this study is to assess the improvement in physician’s knowledge and skill sets in ultrasonography after the implementation of simulation-based educational program. Numeración de páginas Estudios clínicos Ir a página 11 Ir a página 22 Ir a página 33 Ir a página 44 SiguientePróxima página Cuidados intensivosSeccionesSolicita una consultaDescripción generalAnálisis y procedimientosEnfermedades tratadasMédicosMédicos por sede y especialidadEnsayos clínicosInvestigaciónExperiencias en Mayo Clinic y nuestros pacientes cuentan su historiaNoticias de Mayo ClinicComunícate con nosotrosRecursos para profesionales en Medicina Investigación: todo es por los pacientes SeccionesSolicita una consultaDescripción generalAnálisis y procedimientosEnfermedades tratadasMédicosMédicos por sede y especialidadEnsayos clínicosInvestigaciónExperiencias en Mayo Clinic y nuestros pacientes cuentan su historiaNoticias de Mayo ClinicComunícate con nosotrosRecursos para profesionales en Medicina ORG-20399494 Departamentos y centros Centros y departamentos médicos Cuidados intensivos