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Afecciones destacadas Tumor cerebral, cáncer de mama, cáncer de colon, enfermedad cardíaca congénita, arritmia cardíaca. Para ver más afecciones.
Afecciones destacadas
A continuación se enumeran ensayos clínicos actuales.
Filtrar esta lista de estudios según la ubicación, el estado del estudio y más.
Rochester, Minn.
This phase II trial studies how well reduced doses of radiation therapy to the brain and spine (craniospinal) and chemotherapy work in treating patients with newly diagnosed type of brain tumor called WNT)/Wingless (WNT)-driven medulloblastoma. Recent studies using chemotherapy and radiation therapy have been shown to be effective in treating patients with WNT-driven medulloblastoma. However, there is a concern about the late side effects of treatment, such as learning difficulties, lower amounts of hormones, or other problems in performing daily activities. Radiotherapy uses high-energy radiation from x-rays to kill cancer cells and shrink tumors. Drugs used in chemotherapy, such as cisplatin, vincristine sulfate, cyclophosphamide and lomustine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving reduced craniospinal radiation therapy and chemotherapy may kill tumor cells and may also reduce the late side effects of treatment.
The purpose of this trial is to identify cancer survivors who are at increased risk of developing late-occurring complications after undergoing treatment for childhood cancer. A patient's genes may affect the risk of developing complications, such as congestive heart failure, heart attack, stroke, and second cancer, years after undergoing cancer treatment. Genetic studies may help doctors identify survivors of childhood cancer who are more likely to develop late complications.
The primary purpose of this study is to analyze maxillary transverse dimensions in children who have completed polysomnography (PSG), using McNamara’s Criteria and Andrew’s Six Elements.
The purpose of this study is to assess the impact of using real-time, audio-video consults for the Transport Risk Index of Physiologic Stability (TRIPS) Score for Outborn Neonates.
The primary aims of this study are to 1) evaluate the acceptability of implementing a novel transition program for adolescents with epilepsy; 2) evaluate the needs of patients and their families as they prepare for transition from pediatric to adult care; and 3) improve transition readiness and outcomes in youths with epilepsy.
Scottsdale/Phoenix, Ariz.
The purpose of this study is to to genomically characterize pectus excavatum trios (proband + 2 affected family members) for the purpose of identifying candidate genes that may be causal in families with multiple pectus excavatum affected members.
The purpose of this study is to determine the percentage of subjects with confirmed inhibitors (per CDC laboratory criteria; >0.5 Nijmegen Bethesda Units for hemophilia A and >0.3 Nijmegen Bethesda Units for hemophilia B within the first 50 Exposure Days (ED).
The main objective of this study is to establish a national pediatric obesity registry known as POWER (Pediatric Obesity Weight Evaluation Registry). This registry will contain clinical data from individual comprehensive pediatric weight management programs around the United States for overweight and obese youth.
Jacksonville, Fla., Rochester, Minn.
The purpose of this study is to assist child health providers to better understand and support pediatric patient clinical care needs related to experiences of interpersonal discrimination.
The purpose of this study is to evaluate how well veliparib, radiation therapy, and temozolomide work in treating participants with newly diagnosed malignant glioma without H3 K27M or BRAFV600E mutations. Veliparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving veliparib, radiation therapy, and temozolomide may work better in treating participants with newly diagnosed malignant glioma without H3 K27M or BRAFV600E mutations.