Biographical summary
Benjamin Lai, M.B., B.h., B.A.O., M.D., is a family medicine physician at Mayo Clinic in Rochester, Minnesota, where he cares for people in the community and surrounding areas. Dr. Lai's clinical practice focuses on the prevention, diagnosis, and treatment of substance use disorders and the management of chronic pain through a comprehensive, individualized approach. He is committed to helping patients navigate complex health challenges by integrating medical, behavioral, and social support strategies into their care.
In addition to his clinical work, Dr. Lai leads as Medical Director of the Mayo Clinic Enterprise Opioid Stewardship Program and serves as an Assistant Professor of Family Medicine. His care philosophy reflects a deep commitment to whole-person care: "I believe in caring for the whole person through a biopsychosocial-spiritual approach. I value the opportunity to listen, connect, and partner with my patients in their care. While I strive to be a trusted resource for them, I equally value the perspectives, experiences, and lessons they share with me."
Areas of expertise
Dr. Lai partners with his patients to address their medical needs through evidence-based treatments and collaborative decision-making. His areas of expertise include:
- Substance use disorder care: Comprehensive evaluation and medication-assisted treatment, including buprenorphine therapy.
- Chronic pain management: Non-opioid and opioid stewardship strategies for safe and effective pain control.
- Mental health support: Integrated care for depression, anxiety, and related conditions as part of primary care.
- Attention-deficit/hyperactivity disorder (ADHD): Diagnosis and ongoing management within a family medicine framework.
- Joint injections: Therapeutic injections for musculoskeletal pain and inflammation.
- Occipital nerve blocks: Targeted treatment for chronic headaches or occipital neuralgia symptoms.
- Long-acting reversible contraception: Insertion and removal for timing and planning of family goals.
- Dermatologic procedures: Skin biopsies and toenail removal performed in an outpatient setting.
Research and professional highlights
Dr. Lai is an Assistant Professor of Family Medicine and Medical Director of the Mayo Clinic Enterprise Opioid Stewardship Program, where he leads initiatives to optimize safe prescribing and improve patient outcomes. Board-certified in family medicine and addiction medicine, he plays an active role in advancing quality improvement and clinical education.
He dedicates part of his professional time to the Centers for Disease Control and Prevention's Division of Overdose Prevention as a Subject Matter Expert, contributing to the development of national clinical quality measures aligned with the 2022 CDC Clinical Practice Guideline for Prescribing Opioids. His scholarly work spans opioid stewardship, substance use disorder treatment, and integrating mental health care into primary care.
Personal note
Outside of his professional commitments, Dr. Lai enjoys traveling, training for half-marathons and marathons, and learning new languages.
Conditions treated
Interests
- Opioid use disorder
- Medications for opioid use disorder (MOUD)
- Chronic non-cancer pain management and research
- Substance use disorder
- Quality improvement in patient care
Mayo Clinic locations
Education
- 2023
Certificate - Clinical and Translational Science Mayo Clinic in Rochester
- 2015
ResidentFamily Medicine, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
- 2015
Academic Chief ResidentFamily Medicine, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
- 2012
Bachelor - Bachelor of Medicine, Bachelor of Surgery & Bachelor of Obstetrics
(MB BCh BAO)University College Cork
- 2007
Master of Science - Neurological Sciences
Thesis: Basal and Stress-Reactive Cortisol Levels in Patients with Inflammatory Bowel Diseases
(Advisors: Sonia Lupien, PhD & Gary Wild, MD PhD)McGill University
- 2005
Bachelor - Bachelor of Science (Major: Physiology; Minor: Psychology)McGill University
Activities and honors
Certifications
- 2026
Addiction MedicineAmerican Board of Preventive Medicine
- 2015
Family MedicineAmerican Board of Family Medicine
Awards and honors
- 2025
Excellence Through Teamwork AwardMayo Clinic
- 2024
Innovation Educator AwardMayo School of Continuous Professional Development (MSCPD)
- 2024
Population Health Scholar Alumni AwardMayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery
- 2024
2024 Kern Center AwardMayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery
- 2023
2023 Kern Center AwardMayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery
- 2021
Population Health ScholarMayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery
- 2017
Awardee Steven M. Thompson Physician Corps Loan Repayment Program
- 2012
Winner of Interactive Case of the Year (2011)Society for Vascular Medicine Annual Meeting
- 2010
Joint winner of the P.F. Fitzpatrick Prize in Epidemiology & Public HealthUniversity College of Cork
- 2010
Second Prize Winner of the Dr. H. H. Stewart Scholarship in Public HealthNational University of Ireland
- 2009
Second Prize Winner of the Dr. H. H. Stewart Scholarship in BiochemistryNational University of Ireland
- 2008
The title of “College Scholar” Title awarded to top 10% of class for academic performanceUniversity College Cork
- 2007
Dean’s Honor List for M.Sc. ThesisMcGill University
Professional memberships
- 2026 - present
MemberAmerican Society of Addiction Medicine
- 2025 - present
MemberMayo Clinic Pharmaceutical Formulary Committee Anesthesia/Analgesia Sedation Task Force
- 2023 - present
Medical EditorDepartment of Health Education and Content Services
- 2023 - present
MemberMinnesota Department of Human Services
- 2023 - present
MemberPharmacy and Therapeutics Subcommittee, Mayo Clinic
- 2023 - present
MemberOlmsted County
- 2022 - present
ChairOpioid Stewardship Program Oversight Group
- 2022 - present
LeadKnowledge Content Board - Pain Medicine, AskMayoExpert
- 2022 - 2023
MemberMinnesota Medical Association
- 2022 - present
DelegateMinnesota Academy of Family Practice
- 2022 - present
MemberPain and Opioid Subcommittee (Mayo Alix School of Medicine)
- 2021 - 2022
MemberAgency for Healthcare Research and Quality's Management of Opioid Use and Misuse in Older Adults Initiative
- 2021
MemberMinnesota Department of Health Services
- 2019 - present
MemberDepartment of Family Medicine Medication Assisted Therapy (MAT) Workgroup
- 2019 - 2021
Committee ChairFamily Medicine Morbidity and Mortality Committee
- 2019 - 2020
MemberNortheast Clinic Operations Committee, Mayo Family Clinic Northeast, Department of Family Medicine
- 2019 - 2025
Meeting ChairPrimary Care in Rochester and Kasson Controlled Substance Advisory Group (CSAG)
- 2018 - present
MemberMinnesota Academy of Family Physicians
- 2017 - 2018
MemberAdventist Health Feather River Outpatient Committee
- 2017 - 2018
MemberAdventist Health Feather River Outpatient Clinic Opioid Oversight Committee
- 2017 - 2018
ChairAdventist Health Feather River Outpatient Clinic Narcotic Task Force
- 2017 - 2018
RepresentativeAdventist Health Market Operating Council Quality Sub-Committee
- 2015 - 2018
MemberCalifornia Academy of Family Physicians
- 2015 - present
MemberAmerican Academy of Family Physicians
- 2015 - present
MemberAmerican Medical Association
- 2015 - present
MemberThe College of Family Physicians Canada
- 2014 - 2015
MemberMayo Clinic Graduate Education Committee
- 2013 - 2015
Resident MemberMayo Clinic Family Medicine Research Committee
- 2012 - 2014
Resident MemberMayo Kasson Family Clinic SBIRT Committee
Publications