Linda B. Baughn, Ph.D.

Location

  1. Rochester, Minnesota

Idiomas

English

Linda B. Baughn, Ph.D., FACMG, has a broad translational research background in cancer biology with a focused clinical genomics interest in hematologic malignancies, specifically multiple myeloma. In addition to her role as a co-director of the Clinical Genomics Laboratory and board-certified clinical laboratory cancer geneticist, she has been actively engaged in myeloma translational research since 2004.

Focus areas

  • Clinical: Improved clinical diagnostic approaches for hematologic malignancies. Utilization of next-generation sequencing techniques in the characterization of genomic abnormalities such as structural and copy number variations in patients with multiple myeloma and other hematologic malignancies including AML and B-ALL.
  • Translational Research: Understanding multiple myeloma drug resistance. Identification of novel biomarkers of drug sensitive and resistant myeloma cells using genetic models and multiparameter time of flight mass cytometry (CyTOF). CyTOF can be used to phenotypically characterize single cells using numerous antibody combinations to identify rare subpopulations and appreciate clonal heterogeneity.
  • Translational Research: Health disparity research. African Americans are two to three times more likely to develop multiple myeloma. It is important to elucidate mechanisms of this racial disparity. Dr. Baughn and colleagues have utilized genotyping data from single nucleotide polymorphisms that are ancestrally informative to calculate individual ancestry as a novel approach rather than relying only on self-report ancestry to understand health disparities of multiple myeloma.
  • Multiple myeloma
  • Acute myeloid leukemia
  • B cell acute lymphoblastic leukemia
  1. 2004
    Ph.D. - ImmunologyTufts University

Certificaciones

  1. 2017
    Clinical Molecular Genetics and GenomicsAmerican Board of Medical Genetics and Genomics
  2. 2015
    Clinical Cytogenetics and GenomicsAmerican Board of Medical Genetics and Genomics

Reconocimientos y distinciones

  1. 2012
    Early Career Faculty Travel GrantThe American Association of Immunologists
  2. 2009
    NIH Training Program in Immunology Albert Einstein College of Medicine
  3. 2006
    Travel AwardThe American Society of Hematology
  4. 2006
    Career Development FellowshipThe Leukemia and Lymphoma Society
  5. 2004
    NIH Training Program in Immunology Cornell University

Publicaciones

Actividades de investigación

See a description of research activities.