Kenneth D. Aldape, M.D.

  1. Pathologist
  1. Lochner RH, Powell SZ, Fung KM, Zhang YJ, Baskin D, Tremont-Lukats IW, Desai R, Dunn IF, Battiste JD, Hrachova M, Hardcastle J, Nazem A, Smoley SA, Isaacson M, Dasari S, Gandham M, Cimino PJ, Quezado M, Abdullaev Z, Pratt D, Aldape K, Jenkins R, Ida CM. FGFR1 fusions in genomically and epigenetically bona fide glioblastoma, IDH-wildtype. J Neuropathol Exp Neurol. 2026 Jan 1; 85 (1):98-102
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  2. van den Bent MJ, Ghisai SA, Wick W, Sanson M, Brandes AA, Clement PM, Erridge SC, Vogelbaum MA, Nowak AK, Baurain JF, Mason WP, Wheeler H, Tabouret E, Gill S, Griffin M, Taal W, Ruda R, Weller M, McBain C, Reijneveld JC, Enting RH, Tran S, Lesimple T, Kocher M, Gijtenbeek A, Lim E, Herrlinger U, Hau P, Dhermain F, Aldape K, Jenkins RB, Dubbink HJ, Kros JM, Wesseling P, Hoogstrate Y, Nuyens S, Golfinopoulos V, Tesileanu CMS, Gorlia T, French P, Baumert BG. Concurrent and adjuvant temozolomide for 1p/19q non-co-deleted anaplastic glioma (CATNON; EORTC study 26053-22054): final and exploratory analyses of a randomised, open-label, phase 3 trial. Lancet Oncol. 2026 Jan; 27 (1):45-56
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  3. Landry AP, Wang JZ, Patil V, Ajisebutu A, Gui C, Yefet LS, Ellenbogen Y, Liu J, Mamatjan Y, Wei Q, Singh O, Mansouri S, Ehret F, Capper D, Cohen-Gadol AA, Tabatabai G, Tatagiba M, Behling F, Barnholtz-Sloan JS, Sloan AE, Chambless LB, Mansouri A, Makarenko S, Yip S, Tsang DS, Gao A, Aldape K, Nassiri F, Zadeh G, International Consortium On Meningiomas (ICOM). A framework for using DNA methylation-based modelling for the clinical management of cranial meningioma. Neuro Oncol. 2025 Nov 19 [Epub ahead of print]
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  4. Huynh V, Zhang D, Raghunathan A, Hardcastle J, Smoley S, Isaacson M, Gandham M, Dasari S, Abdullaev Z, Aldape K, Quezado M, Pratt D, Cimino PJ, Lachance D, Ida CM. SLC44A1::PRKCA fusion-positive glioneuronal tumor without histological and epigenetic features of papillary glioneuronal tumor. J Neuropathol Exp Neurol. 2025 Nov 12 [Epub ahead of print]
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  5. Yefet LS, Landry AP, Wang JZ, Liu J, Patil V, Gui C, Ajisebutu A, Ellenbogen Y, Mamatjan Y, Yakubov R, Kaloti R, Persaud P, Wei Q, Singh O, Mansouri S, Bunda S, Cohen-Gadol AA, Tabatabai G, Tatagiba M, Behling F, Barnholtz-Sloan JS, Sloan AE, Chotai S, Chambless LB, Mansouri A, Agnihotri S, Makarenko S, Yip S, Tsang DS, Aldape K, Gao A, Nassiri F, Zadeh G. Assessment of Molecular Tools in Pediatric, Adolescent and Young Adult Meningioma Highlights the Need for Lifespan Precision in Neuro-Oncology. Neuro Oncol. 2025 Nov 8 Epub 2025 Nov 08
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  6. Huynh V, Vizcaino MA, Schwartz JD, Wilson JZ, Daniels DJ, Guerin JB, Kipp BR, Orr BA, Aldape K, Zhu Y. A posterior fossa mass in a 4-year-old female. Brain Pathol. 2025 Nov; 35 (6):e70028 Epub 2025 June 24
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  7. Cook DJ, Decker PA, Hardcastle JJ, Kollmeyer TM, Smoley SA, Isaacson MD, Gandham M, Dasari S, Abdullaev Z, Aldape K, Quezado M, Cimino PJ, Pratt DW, Giannini C, Nguyen A, Raghunathan A, Trejo-Lopez JA, Vaubel RA, Vizcaino MA, Mendoza CJZ, Al Kateb H, Jenkins RB, Ida CM. EGFR transcript variants: Potential diagnostic biomarker for glioblastoma, IDH-wildtype? J Neuropathol Exp Neurol. 2025 Nov 1; 84 (11):1059-1062
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  8. Gui C, Wang JZ, Patil V, Landry AP, Singh O, Castelo-Branco P, Tabori U, Aldape K, Behling F, Barnholtz-Sloan JS, Horbinski C, Tabatabai G, Ajisebutu A, Liu J, Patel Z, Yakubov R, Kaloti R, Ellenbogen Y, Wilson C, Cohen-Gadol A, Tatagiba M, Holland EC, Sloan AE, Chotai S, Chambless LB, Gao A, Makarenko S, Yip S, Nassiri F, Zadeh G, International Consortium on Meningiomas (ICOM). Analysis of TERT association with clinical outcome in meningiomas: a multi-institutional cohort study. Lancet Oncol. 2025 Sep; 26 (9):1191-1203
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  9. Wen PY, Weller M, Lee EQ, Touat M, Khasraw M, Rahman R, Platten M, Lim M, Winkler F, Horbinski C, Verhaak RGW, Huang RY, Ahluwalia MS, Albert NL, Tonn JC, Schiff D, Barnholtz-Sloan JS, Ostrom Q, Aldape KD, Batchelor TT, Bindra RS, Chiocca EA, Cloughesy TF, DeGroot JF, French P, Galanis E, Galldiks N, Gilbert MR, Hegi ME, Lassman AB, Le Rhun E, Mehta MP, Mellinghoff IK, Minniti G, Roth P, Sanson M, Taphoorn MJB, von Deimling A, Weiss T, Wick W, Zadeh G, Reardon DA, Chang SM, Short SC, van den Bent MJ, Preusser M. Glioblastoma in Adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) Consensus Review on Current Management and Future Directions. Neuro Oncol. 2025 Aug 13 [Epub ahead of print]
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  10. Cook DJ, Trejo-Lopez JA, Pitel BA, Saha N, Koganti T, Hardcastle J, Smoley S, Isaacson M, Gandham M, Sivasankaran G, Dasari S, Fung KM, Powell SZ, Trivedi D, Abdullaev Z, Aldape K, Quezado M, Pratt D, Cimino PJ, Edgar MA, Vaubel RA, Raghunathan A, Giannini C, Jenkins RB, Ida CM. Expanding the spectrum of TERT promoter mutations in CNS tumors: A case series of non-canonical mutations. J Neuropathol Exp Neurol. 2025 Aug 1; 84 (8):746-748
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  11. Sahm F, Aldape KD, Brastianos PK, Brat DJ, Dahiya S, von Deimling A, Giannini C, Gilbert MR, Louis DN, Raleigh DR, Reifenberger G, Santagata S, Sarkar C, Zadeh G, Wesseling P, Perry A. cIMPACT-NOW update 8: Clarifications on molecular risk parameters and recommendations for WHO grading of meningiomas. Neuro Oncol. 2025 Feb 10; 27 (2):319-330
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  12. Youngblood MW, Tran AN, Wang W, An S, Scholtens D, Zhang L, O'Shea K, Pokorny JL, Magill ST, Sachdev S, Lukas RV, Ahmed A, Unruh D, Walshon J, McCortney K, Wang Y, Baran A, Sahm F, Aldape K, Chandler JP, David James C, Heimberger AB, Horbinski C. Docetaxel targets aggressive methylation profiles and serves as a radiosensitizer in high-risk meningiomas. Neuro Oncol. 2023 Mar 14; 25 (3):508-519
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  13. Raghunathan A, Ida CM, Westbroek EM, Gupta S, Jenkins RB, Giannini C, Aldape KD. Mutations of FH and IDH may induce gliomagenesis by similar mechanisms. J Neuropathol Exp Neurol 2022 Dec 19; 82 (1):99-100
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  14. Pratt D, Lucas CG, Selvam PP, Abdullaev Z, Ketchum C, Quezado M, Armstrong TS, Gilbert MR, Papanicolau-Sengos A, Raffeld M, Choo-Wosoba H, Chan P, Whipple N, Nasrallah M, Santi M, Ramaswamy V, Giannini C, Ritzmann TA, Grundy RG, Burford A, Jones C, Hawkins C, Venneti S, Solomon DA, Aldape K. Recurrent ACVR1 mutations in posterior fossa ependymoma. Acta Neuropathol. 2022 Aug; 144 (2):373-376 Epub 2022 May 19
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  15. Chen H, Thomas C, Munoz FA, Alexandrescu S, Horbinski CM, Olar A, McGuone D, Camelo-Piragua S, Wang L, Pentsova E, Phillips J, Aldape K, Chen W, Iafrate AJ, Chi AS, Zagzag D, Golfinos JG, Placantonakis DG, Rosenblum M, Ohman-Strickland P, Hameed M, Snuderl M. Polysomy is associated with poor outcome in 1p/19q codeleted oligodendroglial tumors. Neuro Oncol. 2019 Sep 6; 21 (9):1164-1174
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  16. Suppiah S, Nassiri F, Bi WL, Dunn IF, Hanemann CO, Hashizume R, James CD, Mawrin C, Noushmehr H, Perry A, Sahm F, Sloan A, Von Deimling A, Wen PY, Aldape K, Zadeh G, International Consortium on Meningiomas. Molecular and translational advances in meningiomas. Neuro Oncol. 2019 Jan 14; 21 (Suppl 1):i4-i17
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  17. GLASS Consortium. Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium. Neuro Oncol. 2018 Jun 18; 20 (7):873-884
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