Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.


Mayo Clinic specialists are actively involved in research on new therapies for esophagitis. You may have access to experimental treatments for eosinophilic esophagitis not available elsewhere, such as cytosponge to monitor treatment results. Researchers are also studying ways to improve diagnosis and treatment of Barrett's esophagus, including minimally invasive treatments.

Barrett's esophagus

Researchers are investigating novel imaging techniques to detect early cancer changes in Barrett's esophagus and advanced endoscopy to treat Barrett's esophagus and early cancers. They are also researching medications that can decrease cancer risk and genetic factors that may be related to Barrett's esophagus.

Read more about research in the Barrett's Esophagus Laboratory.

Eosinophilic esophagitis

Mayo Clinic is a leader in eosinophilic esophagitis research and actively researches eosinophilic disorders. Mayo researchers have tested the effects of many medications on treatment, including steroids, asthma medications and acid-blocking medications.

Clinical trials are underway to study long-term management and remission of eosinophilic esophagitis. Mayo Clinic researchers are also studying the use of a device called the Cytosponge as a replacement for endoscopy to monitor ongoing treatment for eosinophilic esophagitis.

The Cytosponge is a small sponge inside a capsule attached to a string. You swallow the capsule, which dissolves; the doctor then pulls out the sponge, scraping cells off your esophagus. It's quick, inexpensive, minimally invasive and does not require anesthesia.

The Allergic Diseases Research Laboratory at Mayo Clinic's campus in Rochester, Minnesota, investigates the mechanisms of common airway and skin diseases. The lab focuses on and studies types of immune cells (white blood cells), especially eosinophils. Laboratories in the areas of clinical immunology and immunotherapeutics, immunology, and gastroenterology and hepatology also are involved in research on eosinophilic disorders.


See a list of publications by Mayo doctors on esophagitis disease on PubMed, a service of the National Library of Medicine.