Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Departments that treat this condition

Areas that research this condition


Mayo Clinic researchers actively study cluster headaches and other types of headaches. Researchers study new medications and treatment options to help prevent and treat cluster headaches. Read more about Mayo Clinic headache research.

Researchers are studying promising new cluster headache treatments, including:

  • Occipital nerve stimulation. Researchers are studying the effectiveness of occipital nerve stimulation, a procedure in which your surgeon implants electrodes in the back of your head and connects them to a small generator. The electrodes send impulses to stimulate the area of the occipital nerve, which may block or relieve your pain signals.
  • Deep brain stimulation. Doctors are researching the treatment of cluster headaches with deep brain stimulation, a procedure in which your surgeon implants an electrode into a specific area of your brain (the hypothalamus) associated with the timing of cluster headache periods. Your surgeon connects the electrode to a generator that changes your brain's electrical impulses and may help relieve your pain.

Read about microstimulators that hold promise for some medically refractory headaches.


See a list of publications about cluster headache by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.