الأدوية والمكملات الغذائية

Proper Use

Drug information provided by: Merative, Micromedex®

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Vigabatrin is only available through a restricted program called the Vigabatrin REMS program. It is very important that you understand the Vigabatrin REMS program and become familiar with the Medication Guide. Talk to your doctor about the program before starting treatment with vigabatrin.

You may take this medicine with or without food.

To use the oral liquid:

• Open the packet and empty the contents into a clean cup.
• Dissolve it with 10 milliliters (mL) of cold or room temperature water.
• Do not use the liquid if it is not clear (or free of particles) and colorless.
• Measure the dose with the oral syringe in the package.
• Throw away any unused liquid after the dose is given.

Vigabatrin may be used together with other seizure medicines. Keep using all of your medicines unless your doctor tells you to stop.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (solution):
  • For infantile spasms:
    • Children 1 month to 2 years of age—Dose is based on body weight and must be determined by your doctor. The starting dose is 50 milligrams (mg) per kilogram (kg) of body weight per day, divided and given 2 times a day. Your doctor may adjust the dose as needed. However, the dose is usually not more than 150 mg per kg per day.
    • Children younger than 1 month of age—Use and dose must be determined by your doctor.
• For oral dosage forms (solution or tablets):
  • For seizures:
    • Adults and children 17 years of age and weighs more than 60 kilograms (kg)—At first, 500 milligrams (mg) two times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.
    • Children 2 to 16 years of age and weighs 10 to 15 kg—Dose is based on body weight and must be determined by your doctor. At first, 175 milligrams (mg) given two times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 1050 mg per day.
    • Children 2 to 16 years of age and weighs 15 to 20 kg—Dose is based on body weight and must be determined by your doctor. At first, 225 milligrams (mg) given two times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 1300 mg per day.
    • Children 2 to 16 years of age and weighs 20 to 25 kg—Dose is based on body weight and must be determined by your doctor. At first, 250 milligrams (mg) given two times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 1500 mg per day.
    • Children 2 to 16 years of age and weighs 25 to 60 kg—Dose is based on body weight and must be determined by your doctor. At first, 250 milligrams (mg) given two times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 2000 mg per day.
    • Children younger than 10 years of age and weighs less than 10 kg—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.