المعلومات عن الأدوية مقدَّمة من: IBM Micromedex
It is very important that your doctor check your progress at regular visits for any unwanted effects or problems that may be caused by this medicine. Blood and urine tests may be needed to check for unwanted effects.
Using this medicine while you are pregnant can harm your unborn baby. If you are a woman who can bear children, your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant. Use a highly effective form of birth control to keep from getting pregnant. You should not become pregnant while you are taking this medicine and for 20 months after stopping it. If you think you have become pregnant while using the medicine, tell your doctor right away.
This medicine may also cause birth defects if the father is using it when his sexual partner becomes pregnant. Male patients (including those who had a vasectomy) should use condoms and spermicides as forms of birth control during sexual intercourse while taking sonidegib and for 8 months after the last dose of this medicine.
Do not donate blood or blood products while taking this medicine and for 20 months after stopping it. Men should not donate semen while taking this medicine and for 8 months after the last dose.
This medicine may increase your risk of serious muscle problems called rhabdomyolysis, that can lead to kidney damage. Tell your doctor right away if you develop new or worsening muscle spams, pain, or tenderness, dark urine, or decreased amount of urine while taking sonidegib.
If you plan to have children, talk with your doctor before using this medicine. Some women using this medicine have become infertile (unable to have children).
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St John's wort) or vitamin supplements.