الأدوية والمكملات الغذائية

Proper Use

Drug information provided by: Merative, Micromedex®

Take this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

In addition to this medicine, your doctor may change your diet to one that is low in fat, sugar, and cholesterol. Carefully follow your doctor's orders about any special diet.

This medicine comes with a patient information insert. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Swallow the tablet whole. Do not crush, break, chew, or dissolve it. You may take this medicine with or without food.

If you are taking darolutamide together with rosuvastatin and ezetimibe combination, your dose should not be higher than 5 milligrams (mg) rosuvastatin and 10 mg ezetimibe per day, unless otherwise directed by your doctor. Do not use more than 10 mg rosuvastatin and 10 mg ezetimibe per day together with regorafenib. When used together with higher doses of rosuvastatin and ezetimibe combination, these medicines may increase your risk of muscle injury.

If you need to take an antacid that contains aluminum and magnesium (eg, Maalox®), take the antacid at least 2 hours after using this medicine.

If you are also using cholestyramine (Questran®), take it at least 4 hours before or 2 hours after you take this medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets):
  • For high cholesterol or homozygous familial hypercholesterolemia (HoFH):
    • Adults —At first, one tablet with 5 milligrams (mg) rosuvastatin and 10 mg ezetimibe once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 40 mg rosuvastatin and 10 mg ezetimibe per day.
    • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Do not take 2 doses of this medicine within 12 hours of each other.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.