المعلومات عن الأدوية مقدَّمة من: IBM Micromedex
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of pembrolizumab injection in children 12 years of age with melanoma or in children with lymphoma, solid tumors, colorectal cancer, Merkel cell carcinoma, microsatellite instability-high cancer, or tumor mutational burden-high cancer. However, safety and efficacy have not been established in children with other cancers.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of pembrolizumab injection in the elderly. However, elderly patients are more likely to have serious unwanted effects, which may require caution in patients receiving this medicine.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
Central nervous system (brain and spinal cord) cancer—Safety and efficacy have not been established in patients with solid tumors in the brain and spinal cord.
Colitis (inflammation of the bowels) or
Diabetic ketoacidosis or
Hepatitis (inflammation of the liver) or
Hyperthyroidism (high levels of thyroid hormone) or
Hypophysitis (inflammation of the pituitary gland) or
Hypothyroidism (low levels of thyroid hormone) or
Immune system problems or
Nephritis (inflammation of the kidneys) or
Pneumonitis (inflammation of the lungs) or
Type 1 diabetes—Use with caution. May make these conditions worse.
Organ transplant (eg, kidney or liver transplant), recent—Use with caution. May increase risk for organ transplant rejection.
Patients who have had allogeneic hematopoietic stem cell transplant (HSCT)—Use with caution. May cause side effects to become worse.
Portions of this document last updated: March 01, 2023
حقوق الطبع والنشر © لعام 2023 محفوظة لصالح IBM Watson Health. جميع الحقوق محفوظة. هذه المعلومات مخصصة لاستخدام المستخدم النهائي فقط، ولا يجوز بيعها أو إعادة توزيعها أو استخدامها بطريقة أخرى للأغراض التجارية.