Proper Use

المعلومات عن الأدوية مقدَّمة من: IBM Micromedex

A home health caregiver or a family member will give you or your child this medicine. It is given as a shot under your skin or into a muscle.

This medicine comes with patient instructions and a training device. Let your home health caregiver or family member read and follow the directions carefully. Ask your doctor if you have any questions.

To use:

  • This medicine is available as an autoinjector and can only be used one time. It is available in 2 dosage strengths: 0.4 milligram (mg)/0.4 milliliter (mL) autoinjector or 2 mg/0.4mL autoinjector.
  • It also contains printed instructions on the device label and a speaker that provides electronic instructions which guides the user through each step of the injection.
  • Inject the medicine into the outer thighs, through clothing, if needed. If you are giving this medicine to a child younger than 1 year of age, you should pinch the thigh muscle while giving the medicine.
  • Do not use the medicine if it is cloudy, discolored, or has large particles in it.
  • Do not remove the red safety guard until you are ready to use it.
  • After giving the first dose of Evzio® to the patient, get emergency medical help right away.
  • Closely watch the patient for signs and symptoms of opioid emergency may return after several minutes.
  • Give a new naloxone injection every 2 to 3 minutes if symptoms returned and monitor the patient until emergency help is received.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form:
    • For opioid emergency:
      • Adults and children—0.4 or 2 milligrams (mg) injected under the skin or into a muscle.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.