Proper Use

Drug information provided by: Merative, Micromedex®

Betaine powder should be mixed with 4 to 6 ounces of juice, milk, or water until completely dissolved. The solution should be used immediately after mixing.

Do not use if the powder does not dissolve completely or gives a colored solution.

Betaine should be taken with meals.

It is important that you follow any special instructions from your doctor, such as taking folic acid, pyridoxine (vitamin B 6), and vitamin B 12 supplements. If you have any questions about this, check with your doctor.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (powder for solution):
    • To prevent buildup of homocysteine:
      • Adults, teenagers, and children 3 years of age and older—The starting dose is usually 3 grams taken two times a day with meals. Your doctor may adjust your dose as needed.
      • Children younger than 3 years of age—The dose is based on body weight and must be determined by your doctor. Betaine should be taken with meals.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.