Mark R. Waddle, M.D.

  1. Radiation Oncologist



  1. Rochester, Minnesota



Mark R. Waddle, M.D., is a radiation oncologist at Mayo Clinic. He treats a wide range of malignant and benign conditions. He values the privilege to provide care to his patients and emphasizes patient education, shared decision making, and providing the most advanced treatment techniques and technology. His areas of clinical focus are the following:

  • Treatment of breast cancer including localized, advanced, and oligometastatic treatment
  • Treatment of genitourinary malignancies including prostate cancer, bladder, cancer, testicular cancer, and penile cancers.
  • Treatment of lung malignancies, including treatment with stereotactic body radiation and intensity modulated radiation therapy.
  • Treatment of head and neck malignancies
  • Treatment of malignancies of the central nervous system

Dr. Waddle's research focuses on health services research and clinical informatics with a special focus on using advances in data science and technology to identify opportunities to improve treatment techniques, reduce complications from treatment, and to improve the patient experience.

Another research focus of Dr. Waddle is in the value and economics of oncology care, with a goal of defining and improving the value of care delivery in the United States on an individual, local, and national level.


Rochester, Minnesota

  1. 2016
    Preliminary Medicine InternshipInternal Medicine Residency Program, Department of Internal Medicine
  2. 2015
    MDUniversity of North Carolina School of Medicine
  3. 2010
    BS with Distinction - ChemistryUniversity of North Carolina at Chapel Hill

Awards and honors

  1. 2020
    Legislation Visitation AwardFlorida Medical Association
  2. 2019
    Mevion Award for Best Abstracts, Third PrizeAmerican College of Radiation Oncology
  3. 2019
    Mayo Brothers Distinguished Fellowship AwardMayo School of Graduate Medical Education, Mayo Clinic College of Medicine and Science, Department of Education Administration
  4. 2018
    Resident Seed GrantAmerican College of Radiation Oncology
  5. 2018
    Capitol Hill Travel AwardAmerican College of Radiology
  6. 2017
    Legislative Visitation AwardFlorida Medical Association
  7. 2017
    Quality Board Recognition AwardMayo School of Continuous Professional Development
  8. 2016
    Best Medical Sponsored Travel Award and Essay Competition WinnerAmerican College of Radiation Oncology
  9. 2015
    Award for Excellence in Patient CareMayo Clinic Above and Beyond Recognition program
  10. 2015
    Deborah C Leary Award, Honorable MentionUniversity of North Carolina School of Medicine
  11. 2010
    John B. Graham Research SocietyUniversity of North Carolina School of Medicine

Professional memberships

  1. 2020 - present
    Committee MemberAmerican Society of Radiation Oncology (ASTRO) Payer Relations Committee
  2. 2020 - present
    Committee MemberAmerican Society of Radiation Oncology (ASTRO) Payment Reform Committee
  3. 2020
    Abstract ReviewerAmerican Society of Radiation Oncology
  4. 2019
    Session ModeratorASTRO
  5. 2019 - 2020
    Vice PresidentMayo Fellows Association
  6. 2019
    Abstract ReviewerAmerican Society of Radiation Oncology
  7. 2019
    Abstract Review and Planning CommitteeASTRO
  8. 2018 - 2020
    Communications Committee MemberAssociation of Residents in Radiation Oncology
  9. 2018 - 2019
    TreasurerMayo Fellows Association
  10. 2018
    Abstract Review and Planning CommitteeASTRO
  11. 2018
    Abstract ReviewerAmerican Society of Radiation Oncology
  12. 2017 - 2020
    Resident MemberGraduate Education Committee
  13. 2017 - 2020
    Resident MemberAdvisory Board for Student Services
  14. 2017 - 2020
    Education Committee MemberAssociation of Residents in Radiation Oncology
  15. 2017 - present
    Quality Oversight Committee MemberDepartment of Radiation Oncology
  16. 2017 - 2018
    Resident MemberFlorida Medical Association
  17. 2017 - present
    Committee MemberHL7 Cancer Interoperability Workgroup
  18. 2016 - 2018
    Social ChairMayo Fellows Association
  19. 2016 - 2017
    Resident MemberDuval County Medical Society Residents' Committee
  20. 2015 - 2016
    Class RepresentativeInternal Medicine, Education Committee, Mayo Graduate School of Medicine
  21. 2015 - present
    Resident/Fellow MemberAmerican Society of Clinical Oncology
  22. 2015 - present
    MemberAmerican College of Radiation Oncology
  23. 2015 - present
    MemberFlorida Medical Association
  24. 2015 - present
    MemberDuval County Medical Society
  25. 2013 - present
    MemberAmerican Society for Radiation Oncology
  26. 2013 - present
    MemberRadiological Society of North America
  27. 2013 - present
    MemberAmerican College of Radiology