Brittany L. Siontis, M.D.

  1. Oncologist
  1. Schuetze SM, Ballman KV, Heise R, Ganjoo KN, Davis EJ, George S, Burgess MA, Choy E, Shepard DR, Tinoco G, Hirbe A, Kelly CM, Attia S, Deshpande HA, Schwartz GK, Siontis BL, Riedel RF, von Mehren M, Kozlowski E, Chen HX, Astbury C, Rubin BP. A Single Arm Phase 2 Trial of Trametinib in Patients With Locally Advanced or Metastatic Epithelioid Hemangioendothelioma. Clin Cancer Res. 2024 Mar 6 Epub 2024 Mar 06
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  2. Heinrich MC, Jones RL, George S, Gelderblom H, Schoffski P, von Mehren M, Zalcberg JR, Kang YK, Razak AA, Trent J, Attia S, Le Cesne A, Siontis BL, Goldstein D, Boye K, Sanchez C, Steeghs N, Rutkowski P, Druta M, Serrano C, Somaiah N, Chi P, Reichmann W, Sprott K, Achour H, Sherman ML, Ruiz-Soto R, Blay JY, Bauer S. Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nat Med. 2024 Feb; 30 (2):498-506 Epub 2024 Jan 05
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  3. Wahlig BD, Broida SE, Rose PS, Robinson SI, Siontis BL, Houdek MT. Is Bone Marrow Aspiration and Biopsy of Clinical Importance in the Initial Staging of Extraskeletal Ewing Sarcoma? Clin Orthop Relat Res. 2023 Nov 1; 481 (11):2177-2182 Epub 2023 Apr 13
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  4. Kowalchuk RO, Mullikin TC, Spears GM, Rose PS, Siontis BL, Kim DK, Costello BA, Morris JM, Gao RW, Shiraishi S, Lucido J, Olivier K, Owen D, Stish BJ, Waddle MR, Laack Ii NN, Park SS, Brown PD, Merrell KW. Assessment of Minimum Dose as a Strong Predictor of Local Failure after Spine SBRT. Int J Radiat Oncol Biol Phys. 2023 Oct 1; 117 (2S):e120-e121
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  5. Lucido J, Mullikin TC, Kowalchuk RO, Rose PS, Siontis BL, Morris JM, Johnson-Tesch B, Thull JC, Brinkmann DH, Phillips R, Laack Ii NN, Park SS, Brown PD, Owen D, Merrell KW. Local Control after Re-Irradiation of Spinal Metastases with Stereotactic Body Radiation Therapy. Int J Radiat Oncol Biol Phys. 2023 Oct 1; 117 (2S):e132
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  6. Gelderblom H, Jones RL, Blay JY, George S, von Mehren M, Zalcberg JR, Kang YK, Razak AA, Trent J, Attia S, Le Cesne A, Siontis BL, Goldstein D, Boye K, Sanchez C, Steeghs N, Rutkowski P, Druta M, Serrano C, Somaiah N, Chi P, Harrow B, Becker C, Reichmann W, Sherman ML, Ruiz-Soto R, Heinrich MC, Bauer S, INTRIGUE investigators. Patient-reported outcomes and tolerability in patients receiving ripretinib versus sunitinib after treatment with imatinib in INTRIGUE, a phase 3, open-label study. Eur J Cancer. 2023 Oct; 192:113245 Epub 2023 July 20
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  7. Degnim AC, Siontis BL, Ahmed SK, Hoskin TL, Hieken TJ, Jakub JW, Baum CL, Day C, Schrup SE, Smith L, Carter JM, Sae-Kho TM, Sae Kho TM, Glazebrook KN, Vijayasekaran A, Okuno SH, Petersen IA. Trimodality Therapy Improves Disease Control in Radiation-Associated Angiosarcoma of the Breast. Clin Cancer Res. 2023 Aug 1; 29 (15):2885-2893
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  8. Houdek MT, Heidenreich MJ, Ahmed SK, Allen-Rhoades W, Siontis BL, Robinson SI, Petersen IA, Rose PS. Treatment outcomes of extraskeletal Ewing sarcoma. J Surg Oncol. 2023 Jul; 128 (1):105-110 Epub 2023 Mar 31
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  9. Ho TP, Dykhoff H, Sangaralingham LR, Siontis BL, Grotz TE, Okuno SH, Robinson SI. Disparities in tyrosine kinase inhibitor use in older patients with gastrointestinal stromal tumors. J Geriatr Oncol 2023 May; 14 (4):101441 Epub 2023 Jan 28
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  10. Houdek MT, Mallett KE, Heidenreich MJ, Ahmed SK, Wenger DE, Smith JH, Siontis BL, Robinson SI, Folpe AL, Petersen IA, Rose PS. Lack of radiosensitivity predicts poor disease specific survival in myxoid liposarcoma. J Surg Oncol. 2023 Apr; 127 (5):848-854 Epub 2022 Dec 27
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  11. Hickman A, Siontis BL. Not All Leiomyosarcomas Are the Same: How to Best Classify LMS. Curr Treat Options Oncol. 2023 Apr; 24 (4):327-337 Epub 2023 Mar 08
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  12. Heater NK, Okuno S, Robinson S, Attia S, Seetharam M, Siontis BL, Yoon J, Chawla S, Milhem MM, Monga V, Skubitz K, Charlson J, Hirbe AC, Weiss MC, Van Tine B, Agulnik M. The Midwest Sarcoma Trials Partnership: Bridging Academic and Community Networks in a Collaborative Approach to Sarcoma. J Clin Med. 2023 Mar 29; 12 (7)
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  13. Kowalchuk RO, Mullikin TC, Florez M, De BS, Spears GM, Rose PS, Siontis BL, Kim DK, Costello BA, Morris JM, Marion JT, Johnson-Tesch BA, Gao RW, Shiraishi S, Lucido JJ, Trifiletti DM, Olivier KR, Owen D, Stish BJ, Waddle MR, Laack NN, Park SS, Brown PD, Ghia AJ, Merrell KW. Development and validation of a recursive partitioning analysis-based pretreatment decision-making tool identifying ideal candidates for spine stereotactic body radiation therapy. Cancer. 2023 Mar 15; 129(6):956-965. Epub 2022 Dec 26.
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  14. Patel MH, Guerrero Vinsard D, Agrawal U, Kendziora RW, Siontis BL, Swaroop Vege S, Sweetser S. Primary Pancreatic Undifferentiated Pleomorphic Sarcoma. ACG Case Rep J. 2023 Mar; 10 (3):e01011 Epub 2023 Mar 22
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  15. Kowalchuk R, Mullikin TC, Breen W, Gits HC, Florez M, De B, Harmsen WS, Rose PS, Siontis BL, Costello BA, Morris JM, Lucido JJ, Olivier KR, Stish B, Laack NN, Park S, Owen D, Ghia AJ, Brown PD, Merrell KW. Development and validation of a unifying pre-treatment decision tool for intracranial and extracranial metastasis-directed radiotherapy. Front Oncol. 2023; 13:1095170 Epub 2023 Mar 27
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  16. Lucido JJ, Mullikin TC, Abraha F, Harmsen WS, Vaishnav BD, Brinkmann DH, Kowalchuk RO, Marion JT, Johnson-Tesch BA, El Sherif O, Brown PD, Rose PS, Owen D, Morris JM, Waddle MR, Siontis BL, Stish BJ, Pafundi DH, Laack NN, Olivier KR, Park SS, Merrell KW. Single and Multifraction Spine Stereotactic Body Radiation Therapy and the Risk of Radiation Induced Myelopathy. Adv Radiat Oncol. 2022 Nov-Dec; 7 (6):101047 Epub 2022 Aug 13
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  17. Kowalchuk RO, Johnson-Tesch BA, Marion JT, Mullikin TC, Harmsen WS, Rose PS, Siontis BL, Kim DK, Costello BA, Morris JM, Gao RW, Shiraishi S, Lucido JJ, Sio TT, Trifiletti DM, Olivier KR, Owen D, Stish BJ, Waddle MR, Laack NN, Park SS, Brown PD, Merrell KW. Development and Assessment of a Predictive Score for Vertebral Compression Fracture After Stereotactic Body Radiation Therapy for Spinal Metastases. JAMA Oncol. 2022 Mar 01; 8(3):412-419.
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  18. Kowalchuk RO, Mullikin TC, Harmsen WS, Rose PS, Siontis BL, Kim DK, Costello BA, Morris JM, Marion JT, Johnson-Tesch BA, Gao RW, Shiraishi S, Lucido JJ, Olivier KR, Owen D, Stish BJ, Laack NN, Park SS, Brown PD, Merrell KW. Development and Internal Validation of a Recursive Partitioning Analysis-Based Model Predictive of Pain Flare Incidence After Spine Stereotactic Body Radiation Therapy. Pract Radiat Oncol. 2022 Jul-Aug; 12(4):e269-e277. Epub 2022 Feb 10.
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  19. Kowalchuk RO, Mullikin TC, Harmsen WS, Rose PS, Siontis BL, Kim DK, Costello BA, Morris JM, Marion JT, Johnson-Tesch B, Gao RW, Shiraishi S, Lucido J, Olivier K, Owen D, Stish BJ, Laack NN 2nd, Park SS, Brown PD, Merrell KW. Development and Internal Validation of an RPA-Based Model Predictive of Pain Flare Incidence After Spine SBRT. Int J Radiat Oncol Biol Phys. 2021 Nov 1; 111 (3S):S60-S61
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  20. Siontis BL, Leja M, Chugh R. Current clinical management of primary cardiac sarcoma. Expert Rev Anticancer Ther. 2020 Jan; 20 (1):45-51 Epub 2020 Jan 09
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  21. Siontis BL, McHugh JB, Roberts E, Zhao L, Thomas DG, Owen D, Baker LH, Biermann JS, Schuetze SM, Chugh R. Differential Outcomes and Biologic Markers of Radiation-Associated vs. Sporadic Osteosarcoma: A Single-Institution Experience. Front Oncol. 2019; 9:1523 Epub 2020 Jan 22
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  22. Waters R, Horvai A, Greipp P, John I, Demicco EG, Dickson BC, Tanas MR, Larsen BT, Ud Din N, Creytens DH, Bahrami A, Doyle LA, Jo VY, Al-Ibraheemi A, Thway K, Jenkins SM, Siontis B, Folpe A, Fritchie K. Atypical lipomatous tumour/well-differentiated liposarcoma and de-differentiated liposarcoma in patients aged View PubMed
  23. Anna Maria Frezza MD, Tarek Assi MD, Salvatore Lo Vullo, Eytan Ben-Ami MD, Armelle Dufresne MD, Kan Yonemori MD, Emi Noguchi MD, Brittany Siontis MD, Richard Ferraro MD, Pawel Teterycz MD, Florence Duffaud MD, Vinod Ravi MD, Bruno Vincenzi MD. Systemic treatments in MDM2 positive intimal sarcoma: A multicentre experience with anthracycline, gemcitabine, and pazopanib within the World Sarcoma Network Cancer. 2019; 126(1):98-104.
  24. Siontis BL, Zhao L, Leja M, McHugh JB, Shango MM, Baker LH, Schuetze SM, Chugh R. Primary Cardiac Sarcoma: A Rare, Aggressive Malignancy with a High Propensity for Brain Metastases. Sarcoma. 2019; 2019:1960593 Epub 2019 Mar 10
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  25. Siontis BL, Chugh R, Schuetze S. The potential of emerging therapeutics for epithelioid sarcoma. Expert Opinion on Orphan Drugs. 2018; 5(12):983-9.
  26. Clay RD, Iyer VN, Reddy DR, Siontis B, Scanlon PD. The "Complex Restrictive" Pulmonary Function Pattern: Clinical and Radiologic Analysis of a Common but Previously Undescribed Restrictive Pattern. Chest. 2017 Dec; 152 (6):1258-1265 Epub 2017 July 17
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  27. Mazur M, Wang F, Hodge DO, Siontis BL, Beinborn DS, Villarraga HR, Lerman A, Friedman PA, Herrmann J. Burden of Cardiac Arrhythmias in Patients With Anthracycline-Related Cardiomyopathy. JACC Clin Electrophysiol. 2017 Feb; 3 (2):139-150 Epub 2016 Sept 28
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  28. Siontis B, Kumar S, Dispenzierei A, Drake MT, Lacy MQ, Budadi F, Dingli D, Kapoor P, Gonsalves W, Gertz MA, Rajkumar SV. Positron emission tomography-computed tomography in the diagnostic evaluation of smoldering multiple myeloma: identification of patients needing therapy. Blood Cancer J. 2015 Dec 24; 5(e364).
  29. Ramar K, Siontis BL. In Reply – Early goal directed therapy for severe sepsis. Mayo Clinic Proceedings. 2015; 90(4):557-8.
  30. Siontis B, Elmer J, Dannielson R, Brown C, Park J, Surani S, Ramar K. Multifaceted interventions to decrease mortality in patients with severe sepsis/septic shock-a quality improvement project. PeerJ. 2015; 3:e1290 Epub 2015 Oct 20
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  31. Dykstra BL, Ramar K. 19-year-old woman with multiorgan failure and purpura. Mayo Clin Proc. 2014 Dec; 89(12):1718-21.
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  32. Dykstra BL, Ramar K. Meningococcemia and Purpura Fulminans. Mayo Clinic Proceedings. 2014; 89(12):1718-21.