Katherine B. Geiersbach, M.D.

  1. Pathologist
  1. Sukov WR, Zhou J, Geiersbach KB, Keeney GL, Carter JM, Schoolmeester JK. Frequency of HER2 protein overexpression and HER2 gene amplification in endometrial clear cell carcinoma. Hum Pathol. 2023 Jul; 137:94-101 Epub 2023 Apr 23
    View PubMed
  2. Dehner CA, Geiersbach K, Rowsey R, Murugan P, Broski SM, Meis JM, Rosenberg AE, Folpe AL. Rhabdomyosarcoma Arising in Inflammatory Rhabdomyoblastic Tumor: A Genetically Distinctive Subtype of Rhabdomyosarcoma. Mod Pathol. 2023 Jun; 36 (6):100131 Epub 2023 Feb 12
    View PubMed
  3. Han SH, O'Toole TR, Meyer RG, Geiersbach KB, Islam MN, Cheng L, Lai J. Clear-cell Variant of Mucoepidermoid Carcinoma Presenting as a Palatal Mass in a 10-Year-old Boy. Anticancer Res. 2023 Feb; 43 (2):939-942
    View PubMed
  4. Geiersbach KB, Gliem TJ, Jenkins SM, Gaitatzes AG, Brodersen PR, Negro ME, Clees MJ, Swanson KE, Boeckman RM, Natrop TJ, Sukov WR, Shah KK, Greipp PT, Rowsey RA, Flotte TJ, Erickson LA, Guo R. Single-Nucleotide Polymorphism Array for Histologically Ambiguous Melanocytic Tumors. J Mol Diagn. 2022 Nov; 24 (11):1160-1170 Epub 2022 Sept 14
    View PubMed
  5. Sivasubramaniam P, Tiegs-Heiden CA, Geiersbach KB, Hagen CE, Sturgis CD, Thangaiah JJ, Hartley CP. Mammary analogue secretory carcinoma: A challenging case arising in a young man with radiation exposure. Ann Diagn Pathol. 2022 Apr; 57:151862 Epub 2021 Nov 22
    View PubMed
  6. Geiersbach KB, Sill DR, Del Rosario KM, Meyer RG, Spears GM, Yuhas JA, Sukov WR, Jenkins RB, Ocal IT, Mounajjed T, Chen B. Detailed Reanalysis of 500 Breast Cancers With Equivocal HER2 Immunohistochemistry and Borderline ERBB2 Fluorescence In Situ Hybridization Results. Am J Clin Pathol. 2021 Oct 13; 156 (5):886-894
    View PubMed
  7. Geiersbach KB, Sill DR, Meyer RG, Yuhas JA, Sukov WR, Mounajjed T, Carter JM, Jenkins RB, Chen B. HER2 Testing for Breast Cancer in the Genomics Laboratory: A Sea Change for Fluorescence In Situ Hybridization. Arch Pathol Lab Med. 2021 Jul 1; 145 (7):883-886
    View PubMed
  8. Zhao Y, Yu H, Ida CM, Halling KC, Kipp BR, Geiersbach K, Rumilla KM, Gupta S, Lin MT, Zheng G. Assessment of RAS Dependency for BRAF Alterations Using Cancer Genomic Databases. JAMA Netw Open. 2021 Jan 04; 4(1):e2035479.
    View PubMed
  9. Geiersbach KB, Chen H, Emmadi R, Haskell GT, Lu X, Liu YJ, Swisshelm K. Current concepts in breast cancer genomics: An evidence based review by the CGC breast cancer working group. Cancer Genet. 2020 Jun; 244:11-20 Epub 2020 Feb 08
    View PubMed
  10. Geiersbach KB, Meyer RG, Sill DR, Mounajjed T, Chen B, Sukov WR, Jenkins RB. Working Up Group 4 Equivocal HER2 Samples Tested by Fluorescence in Situ Hybridization in a Reference Laboratory Setting: Past, Present, and Future. J Clin Oncol. 2020 Jan 10; 38(2):175-176. Epub 2019 Nov 26.
    View PubMed
  11. Blackburn PR, Davila JI, Jackson RA, Fadra N, Atiq MA, Pitel BA, Nair AA, VanDeWalker TJ, Hessler MG, Hovel SK, Wehrs RN, Fritchie KJ, Jenkins RB, Halling KC, Geiersbach KB. RNA sequencing identifies a novel USP9X-USP6 promoter swap gene fusion in a primary aneurysmal bone cyst. Genes Chromosomes Cancer. 2019 Aug; 58(8):589-594. Epub 2019 Mar 06.
    View PubMed
  12. Aypar U, Smoley SA, Pitel BA, Pearce KE, Zenka RM, Vasmatzis G, Johnson SH, Smadbeck JB, Peterson JF, Geiersbach KB, Van Dyke DL, Thorland EC, Jenkins RB, Ketterling RP, Greipp PT, Kearney HM, Hoppman NL, Baughn LB. Mate pair sequencing improves detection of genomic abnormalities in acute myeloid leukemia. Eur J Haematol. 2019 Jan; 102 (1):87-96 Epub 2018 Nov 22
    View PubMed
  13. Geiersbach KB, Bridge JA, Dolan M, Jennings LJ, Persons DL, Souers RJ, Tsuchiya KD, Vasalos PH, Moncur JT. Comparative Performance of Breast Cancer Human Epidermal Growth Factor Receptor 2 Fluorescence In Situ Hybridization and Brightfield In Situ Hybridization on College of American Pathologists Proficiency Tests. Arch Pathol Lab Med. 2018 Oct; 142 (10):1254-1259 Epub 2018 May 07
    View PubMed
  14. Vasmatzis G, Wang X, Smadbeck JB, Murphy SJ, Geiersbach KB, Johnson SH, Gaitatzes AG, Asmann YW, Kosari F, Borad MJ, Serie DJ, McLaughlin SA, Kachergus JM, Necela BM, Thompson EA. Chromoanasynthesis is a common mechanism that leads to ERBB2 amplifications in a cohort of early stage HER2+ breast cancer samples. BMC Cancer. 2018 Jul 13; 18(1):738.
    View PubMed
  15. Stewart RL, Gulbahce EH, Geiersbach KB, Downs-Kelly E. Reply to Commentary on 'HER2 immunohistochemical and fluorescence in situ hybridization discordances in invasive breast carcinoma with micropapillary features'. Mod Pathol 2018 Apr; 31 (4):686
    View PubMed
  16. Haskell GT, Liu YJ, Chen H, Chen B, Meyer RG, Yuhas JA, Geiersbach KB. Integrated Analysis of HER2 Copy Number by Cytogenomic Microarray in Breast Cancers With Nonclassical In Situ Hybridization Results. Am J Clin Pathol. 2018 Jan 29; 149 (2):135-147
    View PubMed
  17. El Jabbour T, Ross JS, Sheehan CE, Affolter KE, Geiersbach KB, Boguniewicz A, Ainechi S, Bronner MP, Jones DM, Lee H. PD-L1 protein expression in tumour cells and immune cells in mismatch repair protein-deficient and -proficient colorectal cancer: the foundation study using the SP142 antibody and whole section immunohistochemistry. J Clin Pathol. 2018 Jan; 71 (1):46-51 Epub 2017 June 30
    View PubMed
  18. Stewart RL, Caron JE, Gulbahce EH, Factor RE, Geiersbach KB, Downs-Kelly E. HER2 immunohistochemical and fluorescence in situ hybridization discordances in invasive breast carcinoma with micropapillary features. Mod Pathol. 2017 Nov; 30 (11):1561-1566 Epub 2017 July 28
    View PubMed
  19. Hui L, Geiersbach KB, Downs-Kelly E, Gulbahce HE. RAI1 Alternate Probe Identifies Additional Breast Cancer Cases as Amplified Following Equivocal HER2 Fluorescence In Situ Hybridization Testing: Experience From a National Reference Laboratory. Arch Pathol Lab Med. 2017 Feb; 141 (2):274-278 Epub 2016 Dec 13
    View PubMed
  20. Zhou W, Geiersbach K, Chadwick B. Rapid removal of cytology slide coverslips for DNA and RNA isolation. J Am Soc Cytopathol. 2017 Jan - Feb; 6 (1):24-27 Epub 2016 Aug 18
    View PubMed
  21. Willmore-Payne C, Damjanovich-Colmenares K, Pasi AV, Werner TL, Gulbahce HE, Downs-Kelly E, Geiersbach KB. Inconsistent Results With Different Secondary Reflex Assays for Resolving HER2 Status. Am J Clin Pathol. 2016 Nov 1; 146 (5):618-626
    View PubMed
  22. Geiersbach KB, Willmore-Payne C, Pasi AV, Paxton CN, Werner TL, Xu X, Wittwer CT, Gulbahce HE, Downs-Kelly E. Genomic Copy Number Analysis of HER2-Equivocal Breast Cancers. Am J Clin Pathol. 2016 Oct; 146 (4):439-47 Epub 2016 Sept 10
    View PubMed
  23. Lynam-Lennon N, Bibby BA, Mongan AM, Marignol L, Paxton CN, Geiersbach K, Bronner MP, O'Sullivan J, Reynolds J, Maher SG. Low miR-187 expression promotes resistance to chemoradiation therapy in vitro and correlates with treatment failure in patients with esophageal adenocarcinoma. Mol Med. 2016 May 23; 22:
    View PubMed
  24. Geiersbach K, Adey N, Welker N, Elsberry D, Malmberg E, Edwards S, Downs-Kelly E, Salama M, Bronner M. Digitally guided microdissection aids somatic mutation detection in difficult to dissect tumors. Cancer Genet. 2016 Jan-Feb; 209 (1-2):42-9 Epub 2015 Dec 15
    View PubMed
  25. Geiersbach K, Adey N, Welker N, Elsberry D, Malmberg EM, Downs-Kelly E, Salama ME, Bronner MP. Milling Microdissection Enriches Tumor Content for Molecular Testing Without Sacrificing Nucleic Acid Yield. Cancer Genet.2016;209:(1-2):42-9.
  26. Zhou L, Palais RA, Paxton CN, Geiersbach KB, Wittwer CT. Copy number assessment by competitive PCR with limiting deoxynucleotide triphosphates and high-resolution melting. Clin Chem. 2015 May; 61: (5)724-33.
    View PubMed
  27. Romero ST, Geiersbach KB, Paxton CN, Rose NC, Schisterman EF, Branch DW, Silver RM. Differentiation of genetic abnormalities in early pregnancy loss. Ultrasound Obstet Gynecol. 2015 Jan; 45: (1)89-94.
    View PubMed
  28. Garrido-Laguna I, Tometich D, Hu N, Ying J, Geiersbach K, Whisenant J, Wang K, Ross JS, Sharma S. N of 1 case reports of exceptional responders accrued from pancreatic cancer patients enrolled in first-in-man studies from 2002 through 2012. Oncoscience. 2015; 2: (3)285-93.
    View PubMed
  29. Leoni C, Stevenson DA, Geiersbach KB, Paxton CN, Krock BL, Mao R, Rope AF. Neural tube defects and atypical deletion on 22q11.2. Am J Med Genet A. 2014 Nov; 164A: (11)2701-6.
    View PubMed
  30. Geiersbach KB, Gardiner AE, Wilson A, Shetty S, Bruyere H, Zabawski J, Saxe DF, Gaulin R, Williamson C, Van Dyke DL. Subjectivity in chromosome band-level estimation: a multicenter study. Genet Med. 2014 Feb; 16 (2):170-5 Epub 2013 July 25
    View PubMed
  31. Jarboe EA, Hirschowitz SL, Geiersbach KB, Wallander ML, Tripp SR, Layfield LJ. Juvenile granulosa cell tumors: immunoreactivity for CD99 and Fli-1 and EWSR1 translocation status: a study of 11 cases. Int J Gynecol Pathol. 2014 Jan; 33: (1)11-5.
    View PubMed
  32. Wilkerson MD, Schallheim JM, Hayes DN, Roberts PJ, Bastien RR, Mullins M, Yin X, Miller CR, Thorne LB, Geiersbach KB, Muldrew KL, Funkhouser WK, Fan C, Hayward MC, Bayer S, Perou CM, Bernard PS. Prediction of lung cancer histological types by RT-qPCR gene expression in FFPE specimens. J Mol Diagn. 2013 Jul; 15: (4)485-97.
    View PubMed
  33. Furtado LV, Jama MA, Paxton CN, Wilson AA, Gardiner AE, Lyon E, Geiersbach KB. Aneuploidy detection in paraffin embedded tissue from products of conception by mini-STR genotyping. Fetal Pediatr Pathol. 2013 Apr; 32: (2)133-50.
    View PubMed
  34. Paxton CN, Brothman AR, Geiersbach KB. Rapid aneusomy detection in products of conception using the KaryoLite BACs-on-Beads assay. Prenat Diagn. 2013 Jan; 33: (1)25-31.
    View PubMed
  35. Furtado LV, Paxton CN, Jama MA, Tripp SR, Wilson AR, Lyon E, Jarboe EA, Thaker HM, Geiersbach KB. Diagnostic utility of microsatellite genotyping for molar pregnancy testing. Arch Pathol Lab Med. 2013 Jan; 137: (1)55-63.
    View PubMed
  36. Adey N, Emery D, Bosh D, Callahan S, Schreiner J, Chen Y, Greig A, Geiersbach K, Parry R. A mill based instrument and software system for dissecting slide-mounted tissue that provides digital guidance and documentation. BMC Clin Pathol. 2013; 13: (1)29.
    View PubMed
  37. Wallander ML, Geiersbach KB, Tripp SR, Layfield LJ. Comparison of reverse transcription-polymerase chain reaction, immunohistochemistry, and fluorescence in situ hybridization methodologies for detection of echinoderm microtubule-associated proteinlike 4-anaplastic lymphoma kinase fusion-positive non-small cell lung carcinoma: implications for optimal clinical testing. Arch Pathol Lab Med. 2012 Jul; 136: (7)796-803.
    View PubMed
  38. Geiersbach KB, Jarboe EA, Jahromi MS, Baker CL, Paxton CN, Tripp SR, Schiffman JD. FOXL2 mutation and large-scale genomic imbalances in adult granulosa cell tumors of the ovary. Cancer Genet. 2011 Nov; 204: (11)596-602.
    View PubMed
  39. Geiersbach KB, Samowitz WS. Microsatellite instability and colorectal cancer. Arch Pathol Lab Med. 2011 Oct; 135: (10)1269-77.
    View PubMed
  40. Geiersbach K, Rector LS, Sederberg M, Hooker A, Randall RL, Schiffman JD, South ST. Unknown partner for USP6 and unusual SS18 rearrangement detected by fluorescence in situ hybridization in a solid aneurysmal bone cyst. Cancer Genet. 2011 Apr; 204: (4)195-202.
    View PubMed
  41. Dames S, Durtschi J, Geiersbach K, Stephens J, Voelkerding KV. Comparison of the Illumina Genome Analyzer and Roche 454 GS FLX for resequencing of hypertrophic cardiomyopathy-associated genes. J Biomol Tech. 2010 Jul; 21: (2)73-80.
    View PubMed