Peyronie's disease is a condition in which a layer of hardened scar tissue (plaque) builds up under the skin of the penis. The plaque commonly causes pain and bending in the penis during erection and may also cause indentations or shortening of the penis. For some men, the changes in the penis' shape make intercourse painful or impossible.
Mayo Clinic in Rochester, Minn., is ranked among the Best Hospitals for urology by U.S. News & World Report. Mayo Clinic in Scottsdale, Ariz., and Mayo Clinic in Jacksonville, Fla., are ranked high performing for urology by U.S. News & World Report.