Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

  1. Changes in uterine bleeding (increased amounts of menstrual bleeding occurring at regular monthly periods
  2. heavier uterine bleeding between regular monthly periods
  3. lighter uterine bleeding between menstrual periods
  4. or stopping of menstrual periods

Less common

  1. Mental depression
  2. skin rash
  3. unexpected or increased flow of breast milk

Incidence not known

  1. Cough
  2. decrease in height
  3. difficulty swallowing
  4. fast heartbeat
  5. hives, itching, puffiness, or swelling of the eyelids or around the eyes, face, lips or tongue
  6. pain in back, ribs, arms, or legs
  7. pain or swelling in arms or legs without any injury
  8. shortness of breath
  9. skin rash
  10. tightness in chest
  11. wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Abdominal pain or cramping
  2. diarrhea
  3. dizziness
  4. fatigue
  5. mild headache
  6. mood changes
  7. nausea
  8. nervousness
  9. pain or irritation at the injection site
  10. swelling of face, ankles, or feet
  11. unusual tiredness or weakness
  12. vomiting
  13. weight gain

Less common

  1. Acne
  2. breast pain or tenderness
  3. brown spots on exposed skin, possibly long-lasting
  4. hot flashes
  5. loss or gain of body, facial, or scalp hair
  6. loss of sexual desire
  7. trouble in sleeping

Not all of the side effects listed above have been reported for each of these medicines, but they have been reported for at least one of them. All of the progestins are similar, so any of the above side effects may occur with any of these medicines.

After you stop using this medicine, your body may need time to adjust. The length of time this takes depends on the amount of medicine you were using and how long you used it. During this period of time, check with your doctor if you notice any of the following side effects:

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Portions of this document last updated: April 01, 2024

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