Before Using

Drug information provided by: Merative, Micromedex®

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Progestins have been used by teenagers and have not been shown to cause different side effects or problems than they do in adults. You must take progestin-only oral contraceptives every day in order for them to work. Progestins do not protect against sexually transmitted diseases, a risk factor for teenagers. It is not known if Depo-Provera Contraceptive Injection causes problems with bone development and growth in teenagers and young women. It is important that your doctor check you regularly for growth problems, especially if you have been using this medicine for 2 years or longer.

Geriatric

This medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

Use of progestin-only contraceptives during pregnancy is not recommended. Doctors should be told if pregnancy is suspected. When accidently used during pregnancy, progestins used for contraception have not caused problems.

Breastfeeding

Although progestins pass into the breast milk, the low doses of progestins used for contraception have not been shown to cause problems in nursing babies. Progestins used for contraception are recommended for nursing mothers when contraception is desired.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

  • Atazanavir
  • Boceprevir
  • Cobicistat
  • Tranexamic Acid

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Amobarbital
  • Amoxicillin
  • Ampicillin
  • Amprenavir
  • Apalutamide
  • Aprepitant
  • Aprobarbital
  • Armodafinil
  • Artemether
  • Bacampicillin
  • Barbital
  • Belzutifan
  • Betamethasone
  • Bexarotene
  • Boceprevir
  • Bosentan
  • Butabarbital
  • Butalbital
  • Carbamazepine
  • Carbenicillin
  • Cefaclor
  • Cefadroxil
  • Cefdinir
  • Cefditoren
  • Cefixime
  • Cefpodoxime
  • Cefprozil
  • Ceftazidime
  • Ceftibuten
  • Cefuroxime
  • Cenobamate
  • Ceritinib
  • Clarithromycin
  • Clobazam
  • Cloxacillin
  • Colesevelam
  • Cyclacillin
  • Cyclosporine
  • Dabrafenib
  • Darunavir
  • Dexamethasone
  • Dicloxacillin
  • Dipyrone
  • Doxycycline
  • Efavirenz
  • Elagolix
  • Elvitegravir
  • Enasidenib
  • Encorafenib
  • Enzalutamide
  • Eslicarbazepine Acetate
  • Eterobarb
  • Etravirine
  • Felbamate
  • Fosamprenavir
  • Fosaprepitant
  • Fosphenytoin
  • Glecaprevir
  • Grazoprevir
  • Griseofulvin
  • Guar Gum
  • Heptabarbital
  • Hexobarbital
  • Indinavir
  • Isotretinoin
  • Ivosidenib
  • Lesinurad
  • Lixisenatide
  • Lopinavir
  • Lorlatinib
  • Lumacaftor
  • Mavacamten
  • Mephobarbital
  • Meropenem
  • Methohexital
  • Minocycline
  • Mitapivat
  • Mitotane
  • Mobocertinib
  • Modafinil
  • Mycophenolate Mofetil
  • Mycophenolic Acid
  • Nafcillin
  • Nelfinavir
  • Nevirapine
  • Octreotide
  • Oxacillin
  • Oxcarbazepine
  • Oxytetracycline
  • Paritaprevir
  • Penicillin G
  • Penicillin G Procaine
  • Penicillin V
  • Pentobarbital
  • Phenobarbital
  • Phenylbutazone
  • Phenytoin
  • Pitolisant
  • Prednisolone
  • Prednisone
  • Primidone
  • Red Clover
  • Repotrectinib
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Rilpivirine
  • Ritonavir
  • Rufinamide
  • Saquinavir
  • Secobarbital
  • Simeprevir
  • St John's Wort
  • Sugammadex
  • Sultamicillin
  • Tazemetostat
  • Telaprevir
  • Telotristat Ethyl
  • Tetracycline
  • Theophylline
  • Thiopental
  • Thioridazine
  • Ticarcillin
  • Tigecycline
  • Tipranavir
  • Tirzepatide
  • Tizanidine
  • Topiramate
  • Troglitazone
  • Ulipristal
  • Voxilaprevir

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:

  • Asthma or
  • Epilepsy, or history of or
  • Heart or circulation problems or
  • Kidney disease, severe or
  • Migraine headaches—May cause fluid buildup and make these conditions worse.
  • Bleeding problems, undiagnosed, such as blood in the urine or changes in vaginal bleeding—May make diagnosis of these problems more difficult.
  • Breast disease (e.g., breast lumps or cysts), history of—May make this condition worse in certain types of diseases that do not react to progestins in a positive way.
  • Central nervous system (CNS) disorders (e.g., depression), or history of or
  • High blood cholesterol or
  • Osteoporosis (brittle bones), or a family history of—May cause these conditions to occur or make these conditions worse.
  • Diabetes mellitus—May cause a mild increase in blood sugar and a need to monitor blood sugar more often.
  • Liver disease—The effects of some progestins may be increased. May make this condition worse.