Before Using

Drug information provided by: Micromedex

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

In deciding whether to use the combined contraceptive vaginal ring as a method of birth control, you need to consider the risks of using it as well as the good it can do. This is a decision you, your sexual partner, and your health care professional will make. For etonogestrel and ethinyl estradiol vaginal ring the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies with this contraceptive ring have been done only in adult patients, and it is not expected to cause different side effects in children than it does in adults. The etonogestrel and ethinyl estradiol vaginal ring is not intended for use in children or adolescents who have not yet started menstruating.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known if this works the same way in younger adults as it does in older adults. There is no specific information comparing the use of etonogestrel and ethinyl estradiol vaginal ring in the elderly with use in other age groups. The etonogestrel and ethinyl estradiol vaginal ring is not intended for use in women older than child-bearing age.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Tranexamic Acid

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Boceprevir
  • Clozapine
  • Crizotinib
  • Dabrafenib
  • Felbamate
  • Fentanyl
  • Isotretinoin
  • Paclitaxel
  • Paclitaxel Protein-Bound
  • Piperaquine
  • Theophylline
  • Tizanidine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Alprazolam
  • Amprenavir
  • Aprepitant
  • Atazanavir
  • Bacampicillin
  • Betamethasone
  • Bexarotene
  • Bosentan
  • Carbamazepine
  • Colesevelam
  • Cyclosporine
  • Darunavir
  • Delavirdine
  • Efavirenz
  • Eslicarbazepine Acetate
  • Etoricoxib
  • Etravirine
  • Fosamprenavir
  • Fosaprepitant
  • Fosphenytoin
  • Ginseng
  • Griseofulvin
  • Lamotrigine
  • Licorice
  • Modafinil
  • Mycophenolate Mofetil
  • Mycophenolic Acid
  • Nelfinavir
  • Nevirapine
  • Oxcarbazepine
  • Phenobarbital
  • Phenytoin
  • Pioglitazone
  • Prednisolone
  • Primidone
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Ritonavir
  • Roflumilast
  • Rosuvastatin
  • Rufinamide
  • Selegiline
  • St John's Wort
  • Telaprevir
  • Tipranavir
  • Topiramate
  • Troglitazone
  • Troleandomycin
  • Valdecoxib
  • Voriconazole
  • Warfarin

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Caffeine
  • Grapefruit Juice

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Abnormal or unusual vaginal bleeding (nonmenstrual)— The use of etonogestrel and ethinyl estradiol vaginal ring may delay diagnosis or worsen this condition. The reason for the bleeding should be determined before etonogestrel and ethinyl estradiol vaginal ring is used.
  • Breast cancer (now or in the past or if suspected) or
  • Cancer of the lining of the uterus, cervix or vagina (now or in the past) or
  • Cancer that worsens when estrogen is present (now or in the past) or
  • Confined to bed or inability to move for long period of time or
  • Coronary artery disease (now or in the past) or
  • Diabetes mellitus with blood vessel problems or
  • Headache (severe) with changes in vision, loss of coordination, inability to move, numbness in arms or legs, or fainting or
  • High blood pressure, severe or
  • Jaundice while using birth control pills or
  • Jaundice during pregnancy or
  • Liver disease (active) or
  • Liver tumors or
  • Surgery (major) or
  • Problems with circulation or blood clots, now or in the past, such as:
  • Blood clots in your brain or
  • Blood clots in your legs or
  • Blood clots in your lungs or
  • Blood clots in your eyes
  • Problems with heart valves—These conditions may increase your chance of serious side effects.
  • Coronary artery disease risk factors such as:
  • Diabetes (sugar diabetes) or
  • High blood pressure or
  • High cholesterol or
  • Obesity—These conditions may increase your chance of serious side effects when using etonogestrel and ethinyl estradiol vaginal ring.
  • Depression or
  • Diabetes mellitus (sugar diabetes) or
  • Headache of type not experience before or
  • High blood pressure or
  • Kidney disease or
  • Migraine headache or
  • Problems with too much insulin in your blood or
  • Problems with too much sugar in your blood—This medication may make this condition worse.
  • Menstrual vaginal bleeding (lack of or heavy)—This problem may occur when contraceptive medicine is stopped, especially if it has happened in the past.
  • Smoking cigarettes—Smoking may increase your chance of serious side effects, especially if you are over 35 years of age or smoke 15 cigarettes or more a day.
  • Swollen ankles, feet, or hands—This medication may make this condition worse. This medicine may also make other medical problems worse when your body keeps too much water or fluid.