Side Effects

Drug information provided by: Micromedex

The risk of serious adverse effects is unlikely for most women using the etonogestrel and ethinyl estradiol vaginal ring. However, oral combination hormonal contraceptives have been associated with unwanted effects which may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not determined

  1. Abdominal fullness
  2. abdominal pain or tenderness usually after eating a meal
  3. blurred vision
  4. changes in skin color
  5. chest pain or discomfort
  6. confusion
  7. constipation
  8. diarrhea
  9. dizziness
  10. gaseous abdominal pain
  11. headache
  12. inability to speak
  13. nausea
  14. nervousness
  15. numbness of hands
  16. pain or discomfort in arms, jaw, back or neck
  17. pain
  18. pains in chest, groin, or legs, especially calves of legs
  19. pounding in the ears
  20. prominent superficial veins over affected area with tenderness and warmth
  21. recurrent fever
  22. seizures
  23. severe headaches of sudden onset
  24. shortness of breath
  25. slow or fast heartbeat
  26. sudden loss of coordination
  27. sudden onset of slurred speech
  28. sudden vision changes
  29. sudden and severe weakness in arm and/or leg on one side
  30. sweating
  31. swelling
  32. swelling of foot or leg on one side of the body
  33. temporary blindness
  34. vomiting or vomiting of blood
  35. yellow eyes or skin

Symptoms of Overdose

  1. Menstrual changes
  2. nausea
  3. vaginal bleeding
  4. vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

  1. Cough
  2. fever
  3. headache
  4. itching of the vagina or genital area
  5. pain during sexual intercourse
  6. pain or tenderness around eyes and cheekbones
  7. sore throat
  8. stuffy or runny nose
  9. thick, white vaginal discharge with no odor or with a mild odor
  10. tightness of chest or wheezing
  11. weight gain

Less common

  1. Crying
  2. depersonalization
  3. false or unusual sense of well-being
  4. hoarseness
  5. mental depression
  6. paranoia
  7. quick to react or overreact emotionally
  8. rapidly changing moods, mild feeling of sadness or discouragement that come and go

Incidence not determined

  1. Absent, missed, or irregular menstrual periods
  2. bloody vaginal discharge
  3. brown, blotchy spots on exposed skin
  4. chills
  5. clay-colored stools
  6. contact lenses intolerance
  7. dark urine
  8. decreased amount or quality of milk
  9. dry mouth
  10. dry skin
  11. fatigue
  12. flushed
  13. fruit-like or unpleasant breath odor
  14. increased hunger
  15. increased thirst
  16. increased urination
  17. loss of appetite
  18. medium to heavy, irregular vaginal bleeding between regular monthly periods, which may require the use of a pad or a tampon
  19. rash
  20. soreness, swelling, or discharge from the breast or breasts
  21. trouble getting pregnant
  22. unexplained weight loss
  23. unusual tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.