Proper Use

Drug information provided by: Micromedex

This medicine is given as a shot under your skin. Adalimumab may sometimes be given at home to patients who do not need to be in the hospital or clinic. If you are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine. Be sure that you understand how to use the medicine.

This medicine comes with a Medication Guide and a Patient Instructions for Use leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

If you use this medicine at home, you will be shown the body areas where this shot can be given. Use a different body area each time you give yourself or your child a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems.

This medicine is available in 2 forms. You may use a Pen or a prefilled syringe.

To use thepen or syringe:

  • First, gather the items you will need on a clean, flat surface using a cloth or towel in a well-lighted area.
  • Wash your hands with soap and water before and after using this medicine.
  • Remove the carton with the syringe or pen from the refrigerator and place it on the cloth.
  • Allow 30 minutes for the syringe or pen to warm up to room temperature. Do not warm this medicine in any other way.
  • Do not remove the needle cover on the prefilled syringe or pen while allowing the medicine to reach room temperature. Remove these immediately before use.
  • Check the liquid in the syringe or pen using the viewing window. It should be clear and colorless. If it is cloudy, discolored, or has particles floating in it, do not use the syringe or pen.
  • Check that the amount of liquid in the pen is the same or close to the fill line seen on the window. The fill line shows a full dose of the medicine. If the pen does not have the full amount of liquid, do not use it. Call your pharmacist.
  • If the liquid is clear, place it on a clean, flat surface. Do not shake the medicine.
  • Check the expiration date on the prefilled syringe or pen, and make sure the date has not passed. Do not use the medicine if the date has passed.
  • Choose an injection site on your body (e.g., thigh, abdomen or stomach area). Clean the injection site with a fresh alcohol wipe and let it dry.
  • Remove the cap or needle cover when you are ready to inject. Inject the medicine within a few minutes after the cap or cover has been removed.
  • Do not inject into skin areas that are red, bruised, tender, or hard. If you have psoriasis, do not inject into a raised, thick, red, or scaly skin patch or into skin lesions.
  • You might have a small amount of blood or liquid at the injection site. Press and hold a dry, clean cotton ball on the injection site for 10 seconds, but do not rub it.
  • Throw away used syringes or pens in a hard, closed container that the needles cannot poke through (puncture-resistant). Keep this container away from children and pets.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage forms (pen or prefilled syringe):
    • For Crohn's disease and ulcerative colitis:
      • Adults—At first (week 0), 160 milligrams (mg) injected under the skin in divided doses. This may be given as four shots in 1 day or as two shots per day for 2 days. Then 2 weeks later, a dose of 80 mg is given. A maintenance dose of 40 mg is given at week 4 and every other week thereafter.
      • Children—Use and dose must be determined by your doctor.
    • For juvenile idiopathic arthritis:
      • Children 4 to 17 years of age weighing 30 kilograms (kg) or more—40 milligrams (mg) injected under the skin every other week.
      • Children 4 to 17 years of age weighing 15 kg and less than 30 kg—20 mg injected under the skin every other week.
      • Children younger than 4 years of age—Use and dose must be determined by your doctor.
    • For plaque psoriasis:
      • Adults—At first, 80 milligrams (mg) injected under the skin, then 40 mg one week after the initial dose and every other week thereafter.
      • Children—Use and dose must be determined by your doctor.
    • For psoriatic arthritis, rheumatoid arthritis, or ankylosing spondylitis:
      • Adults—40 milligrams (mg) injected under the skin every other week. Your doctor may adjust your dose if needed.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store in the refrigerator. Do not freeze.

Protect the medicine from direct light. Keep your medicine and supplies in the original packages until you are ready to use them. Also, when traveling, store the medicine in a cool carrier with an ice pack.