Many patients with inflammatory bowel disease (IBD) fail to respond to standard therapies or lose response over time. But very few of them are truly refractory to treatment.

The chimeric monoclonal anti-CD20 antibody, rituximab, can induce and maintain remission in steroid- and immunomodulator-refractory patients with autoimmune pancreatitis.

Two new studies suggest that the timing of childhood exposure to gluten doesn't increase the risk of celiac disease and that genetic testing may be better than serology for screening high-risk children younger than 2.

No effective treatments exist for primary sclerosing cholangitis other than liver transplantation. Mayo Clinic researchers are now enrolling patients in trials that will evaluate potential PSC therapies, including a medical probiotic, bile acid derivative, monoclonal antibody and curcumin.

Split dosing has consistently proved superior to evening-before dosing for bowel cleansing before colonoscopy. Same-day split-dose regimens may be even more effective.

See all Gastroenterology and Hepatology Clinical Trials at Mayo Clinic

Feb. 23-27, 2015, in Maui, Hawaii
This course covers a wide range of topics in gastroenterology, hepatology and endoscopy.

Oct. 10, 2015, in Phoenix
Designed for local and regional gastroenterologists, family and internal medicine providers, and advanced practice professionals, this course will combine the best of Digestive Disease Week 2015 and the Mayo Gastroenterology & Hepatology 2015 CME course.

See all Gastroenterology Continuous Professional Development courses

Bedside to Bench to Bedside: Individualizing Diagnosis and Therapy for Irritable Bowel Syndrome (IBS)
In this Grand Rounds presentation, Arthur Beyder, M.D., Ph.D., and Gianrico Farrugia, M.D., discuss the effects of SCN5A mutations and polymorphisms on Nav1.5 ion channels in IBS and restoration of loss of function with mexiletine.

Visit the Medical Professional Video Center to view specialty and Grand Rounds presentations

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