Wrinkle creams: Your guide to younger looking skinDo over-the-counter wrinkle creams really reduce the appearance of fine lines and wrinkles? The answer depends on many factors.
By Mayo Clinic Staff
Many wrinkle creams and lotions sold in department stores, in drugstores and on the Internet promise to reduce wrinkles and prevent or reverse damage caused by the sun.
Do they work? That often depends on the specific ingredients and how long you use them. Because these over-the-counter (nonprescription) wrinkle creams aren't classified as drugs, they're not required to undergo scientific research to prove their effectiveness.
If you're looking for a face-lift in a bottle, you probably won't find it in over-the-counter wrinkle creams. The benefits of these products are usually only modest at best.
Common ingredients in anti-wrinkle creams
The effectiveness of anti-wrinkle creams depends in part on the active ingredient or ingredients. Here are some common ingredients that may result in slight to modest improvement in the appearance of wrinkles.
Jun. 27, 2013
- Retinol. Retinol is a vitamin A compound, the first antioxidant to be widely used in nonprescription wrinkle creams. Antioxidants are substances that neutralize free radicals — unstable oxygen molecules that break down skin cells and cause wrinkles.
- Vitamin C. Another potent antioxidant, vitamin C may help protect skin from sun damage. Before and between uses, wrinkle creams containing vitamin C must be stored in a way that protects them from air and sunlight.
- Hydroxy acids. Alpha hydroxy acids, beta hydroxy acids and poly hydroxy acids are exfoliants — substances that remove the upper layer of old, dead skin and stimulate the growth of smooth, evenly pigmented new skin.
- Coenzyme Q10. This ingredient may help reduce fine wrinkles around the eyes and protect the skin from sun damage.
- Tea extracts. Green, black and oolong tea contain compounds with antioxidant and anti-inflammatory properties. Green tea extracts are the ones most commonly found in wrinkle creams.
- Grape seed extract. In addition to its antioxidant and anti-inflammatory properties, grape seed extract also promotes wound healing.
- Niacinamide. A potent antioxidant, this substance is related to Vitamin B-3 (niacin). It helps reduce water loss in the skin and may improve skin elasticity.
See more In-depth
- Nolan KA, et al. Over-the-counter topical skincare products: A review of the literature. Journal of Drugs in Dermatology. 2012;11:220.
- Chien AL, et al. Photoaging. http://www.uptodate.com/home. Accessed May 10, 2013.
- Draelos ZD. The art and science of new advances in cosmeceuticals. Clinics in Plastic Surgery. 2011;38:397.
- How to select anti-aging skin care products. American Academy of Dermatology. http://www.aad.org/dermatology-a-to-z/health-and-beauty/every-stage-of-life/adult-skin/anti-aging-products-selecting. Accessed May 10, 2013.
- Neligan PC. Plastic Surgery. Vol. 2. 3rd ed. London, England: Elsevier Saunders; 2013:26.
- Antoniou C, et al. Photoaging: Prevention and topical treatments. American Journal of Clinical Dermatology. 2010;11:95.
- Visscher MO, et al. Photodamage: Treatments and topicals for facial skin. Facial Plastic Surgery Clinics of North America. 2013;21:61.
- How to maximize results from anti-aging skin care products. American Academy of Dermatology. http://www.aad.org/dermatology-a-to-z/health-and-beauty/every-stage-of-life/adult-skin/anti-aging-products-results. Accessed May 10, 2013.
- Gibson LE (expert opinion). Mayo Clinic, Rochester, Minn. May 16, 2013.