Secondary hypertension (secondary high blood pressure) is high blood pressure that's caused by another medical condition. Secondary hypertension can be caused by conditions that affect your kidneys, arteries, heart or endocrine system. Secondary hypertension can also occur during pregnancy.

Secondary hypertension differs from the usual type of high blood pressure (primary hypertension or essential hypertension), which is often referred to simply as high blood pressure. Primary hypertension has no clear cause and is thought to be linked to genetics, poor diet, lack of exercise and obesity.

Proper treatment of secondary hypertension can often control both the underlying condition and the high blood pressure, which reduces the risk of serious complications — including heart disease, kidney failure and stroke.

Feb. 12, 2016
  1. Textor S. Evaluation of secondary hypertension. http://www.uptodate.com/home. Accessed Jan. 6, 2015.
  2. Gilbert SJ, et al. Secondary hypertension. In: National Kidney Foundation Primer on Kidney Diseases. 6th ed. Philadelphia, Pa.: Elsevier/Saunders; 2014. http://www.clinicalkey.com. Accessed Jan. 6, 2016.
  3. Alpern RJ, et al. Physiology and pathophysiology of hypertension. In: Seldin and Giebisch’s The Kidney. 5th ed. Oxford: Academic Press; 2013. http://www.clinicalkey.com. Accessed Jan. 6, 2016.
  4. Poulter NR, et al. Hypertension. The Lancet. 2015;386:801.
  5. Viera AJ, et al. Diagnosis of secondary hypertension: An age-based approach. American Family Physician. 2010;82:1471.
  6. Overview of hypertension. Merck Manual Professional Version. http://www.merckmanuals.com/professional/cardiovascular-disorders/hypertension/overview-of-hypertension. Accessed Jan. 10, 2016.
  7. Faselis C, et al. Common secondary causes of resistant hypertension and rational for treatment. International Journal of Hypertension. 2011;236239.
  8. Hypertension diagnosis and treatment. Bloomington, Minn.: Institute for Clinical Systems Improvement. https://www.icsi.org/guidelines__more/catalog_guidelines_and_more/catalog_guidelines/catalog_cardiovascular_guidelines/hypertension/. Accessed Jan. 12, 2016.
  9. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. Bethesda, Md.: National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/guidelines/hypertension/jnc7full.htm. Accessed Jan. 15, 2016.
  10. Types of blood pressure medications. American Heart Association. http://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Types-of-Blood-Pressure-Medications_UCM_303247_Article.jsp#.Vpm1bfkrLIU. Accessed Jan. 15, 2016.
  11. Zaporowska-Stachowiak I, et al. Aliskiren – an alternative to angiotensin-converting enzyme inhibitors or angiotensin receptor blockers in the therapy of arterial hypertension. Archives of Medical Science. 2014;10:830.
  12. FDA drug safety communication: New warning and contraindication for blood pressure medicines containing aliskiren (Tekturna). http://www.fda.gov/Drugs/DrugSafety/ucm300889.htm. Accessed Jan. 15, 2016.
  13. Aliskiren. Micromedex Healthcare Series. http://www.micromedex.com. Accessed Jan. 15, 2016.
  14. Your guide to lowering your blood pressure with DASH. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/public/heart/hbp/dash/new_dash.pdf. Accessed Jan. 15, 2016.
  15. Grapefruit. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com . Accessed Jan. 15, 2016.
  16. Sheps SG (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 17, 2016.
  17. Sheps SG. Who’s at risk? In: Mayo Clinic: 5 Steps to Controlling High Blood Pressure. 2nd ed. Rochester, Minn.: Mayo Foundation for Medical Education and Research (MFMER); 2015.