There's no cure for sarcoidosis, but in half of cases it goes away on its own. You may not even need treatment if you don't have significant signs and symptoms of the condition, but you should be monitored with regular chest X-rays and exams of the eyes, skin and any other organ involved.
If your symptoms are severe or organ function is threatened, you will likely be treated with medication.
- Corticosteroids. These powerful anti-inflammatory drugs are usually the first-line treatment for sarcoidosis. In some cases, corticosteroids can be applied directly to an affected area — via a cream to a skin lesion or drops to the eyes.
- Medications that suppress the immune system. Medications like methotrexate (Trexall) and azathioprine (Azasan, Imuran) reduce inflammation by suppressing the immune system.
- Hydroxychloroquine. Hydroxychloroquine (Plaquenil) may be helpful for skin disease and elevated blood-calcium levels.
- Tumor necrosis factor-alpha (TNF-alpha) inhibitors. These medications are commonly used to treat the inflammation associated with rheumatoid arthritis. They can also be helpful in treating sarcoidosis that hasn't responded to other treatments.
Organ transplant may be considered if sarcoidosis has severely damaged your lungs, heart or liver.
March 16, 2017
- Ferri FF. Sarcoidosis. In: Ferri's Clinical Advisor 2016. Philadelphia, Pa.: Mosby Elsevier; 2016. https://www.clinicalkey.com. Accessed Aug. 28, 2015.
- Goldman L, et al., eds. Sarcoidosis. In: Goldman-Cecil Medicine. 25th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. http://www.clinicalkey.com. Accessed Aug. 28, 2015.
- Baughman RP, et al. A concise review of pulmonary sarcoidosis. American Journal of Respiratory and Clinical Care Medicine. 2011;183:573.
- AskMayoExpert. Sarcoidosis. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2015.
- O'Regan A, et al. Sarcoidosis. Annals of Internal Medicine. 2012;156:ICT5.
- Morgenthau AS, et al. Recent advances in sarcoidosis. Chest. 2011;139:174.
- Sanchez M, et al. Sarcoidosis. Dermatologic Clinics. 2015;33:389.
- Statement on sarcoidosis. Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG). American Journal of Respiratory and Critical Care Medicine.1999;160:736.
- Sah BP, et al. Novel pharmacotherapy of sarcoidosis. Pharmacology & Therapeutics. In press. Accessed Nov. 5, 2015.
- Barbara Woodward Lips Patient Education Center. Sarcoidosis. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2015.
- AskMayoExpert. Carciac sarcoidosis. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2017.