Reye's (Ryes) syndrome is a rare but serious condition that causes swelling in the liver and brain. Reye's syndrome most often affects children and teenagers recovering from a viral infection, most commonly the flu or chickenpox.
Signs and symptoms such as confusion, seizures and loss of consciousness require emergency treatment. Early diagnosis and treatment of Reye's syndrome can save a child's life.
Aspirin has been linked with Reye's syndrome, so use caution when giving aspirin to children or teenagers. Though aspirin is approved for use in children older than age 2, children and teenagers recovering from chickenpox or flu-like symptoms should never take aspirin. Talk to your doctor if you have concerns.
Aug. 12, 2014
- Ferri FF. Ferri's Clinical Advisor 2014: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2014. https://www.clinicalkey.com. Accessed May 25, 2014.
- Cherry JD, et al. Feigin and Cherry's Textbook of Pediatric Infectious Diseases. 7th ed. Philadelphia, Pa.: Saunders Elsevier; 2014. https://www.clinicalkey.com. Accessed May 25, 2014.
- NINDS Reye's syndrome information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/reyes_syndrome/reyes_syndrome.htm. Accessed May 25, 2014.
- What is Reye's syndrome? National Reye's Syndrome Foundation. http://www.reyessyndrome.org/what.html. Accessed May 25, 2014.
- Chiriboga CA. Acute toxic-metabolic encephalopathy in children. http://www.uptodate.com/home. Accessed May 25, 2014.
- Reye's syndrome. The Merck Manual for Health Care Professionals. http://www.merckmanuals.com/professional/pediatrics/miscellaneous_disorders_in_infants_and_children/reyes_syndrome.html. Accessed May 26, 2014.
- Medications containing aspirin (acetylsalicylate) and aspirin-like products. National Reye's Syndrome Foundation. http://www.reyessyndrome.org/. Accessed May 28, 2014.
- Renaud DL (expert opinion). Mayo Clinic, Rochester, Minn. June 2, 2014.
You Are ... The Campaign for Mayo Clinic
Mayo Clinic is a not-for-profit organization. Make a difference today.