- Experience. Mayo Clinic is a leading treatment center for people with primary sclerosing cholangitis. The Transplant Center at Mayo Clinic has the largest liver transplant program in the United States and has performed many transplants in people who have primary sclerosing cholangitis. Mayo Clinic is one of the few medical centers in the country that treats bile duct cancer with a liver transplant.
- Expertise. Liver specialists at Mayo Clinic have developed several mathematical models that assess the severity of certain liver diseases. These models help doctors determine where a person ranks on the priority list for a transplant.
- Team approach. Effective treatment of primary sclerosing cholangitis requires coordinated care by several specialties. Liver specialists (hepatologists), endoscopy specialists, pathologists, oncologists, pediatric specialists and surgeons work as a team to provide comprehensive care for adults and children with primary sclerosing cholangitis.
- Continuous improvement. Many Mayo Clinic doctors are involved in clinical trials of new medications for primary sclerosing cholangitis. Researchers at Mayo Clinic are also studying the DNA of people with primary sclerosing cholangitis in hopes of identifying genes that increase the risk of the disease and predict its course.
Liver transplant. Mayo Clinic transplant specialists have performed many transplants in people who have primary sclerosing cholangitis. People with primary sclerosing cholangitis who have liver transplants generally have high survival rates — 80 percent after five years on average. Recipients of liver transplants at Mayo Clinic have above-average survival rates.
Mayo Clinic is also one of the few medical centers in the country to offer liver transplant as a treatment option for bile duct cancer, which develops at much higher rates among people with primary sclerosing cholangitis than in the general population. A multidisciplinary team of Mayo Clinic hepatologists, surgical specialists, radiation oncologists and medical oncologists follows a several-stage treatment plan to prepare people with bile duct cancer for liver transplantation and provide comprehensive medical services during recovery and follow-up.
Mayo Clinic in Rochester, Minn., ranks #1 for digestive disorders in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic in Scottsdale, Ariz., is ranked among the Best Hospitals, and Mayo Clinic in Jacksonville, Fla., is ranked high performing for digestive disorders by U.S. News & World Report. Mayo Clinic also ranks among the Best Children's Hospitals for digestive disorders.
Aug. 15, 2014
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- Barbara Woodward Lips Patient Education Center. Perihilar and distal cholangiocarcinoma. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2013.
- Primary sclerosing cholangitis. American College of Gastroenterology. http://patients.gi.org/topics/primary-sclerosing-cholangitis-psc/. Accessed Jan. 24, 2014.
- Liver health and wellness. American Liver Foundation. http://www.liverfoundation.org/abouttheliver/liverhealth/. Accessed Jan. 24, 2014.
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