Expertise and rankings

Each year Mayo's doctors and surgeons diagnose and treat thousands of people who have liver disease. Mayo Clinic's three-site Liver Transplant Program is one of the largest and most experienced in the country. And the liver transplant teams in Arizona, Florida and Minnesota are leaders and innovators, improving techniques and conducting groundbreaking research, such as:

  • Preclinical work on bioartificial livers and biliary stem cells
  • Active trials on the optimal use of anti-rejection drugs that help ensure positive outcomes

Obesity and liver disease

Talk with your doctor about liver transplant options that improve outcomes.

Click here for an infographic to learn more

People with challenging health situations come to Mayo Clinic for help because our doctors and surgeons are experts in specialized liver transplant options, such as those listed below. The experience, expertise and unique multidisciplinary approach at Mayo Clinic ensure that all options are considered to deliver the most individualized care for every patient. And Mayo has one of the largest living-donor programs in the United States. Living-donor transplant is an option that, for many people, reduces time on the waiting list for a donor liver and improves outcomes.

Nationally ranked

Mayo Clinic's Liver Transplant Program was established in 1985. Since then Mayo Clinic has completed more than 6,700 transplants in children and adults. In 2016, Mayo Clinic's Florida campus completed its 3,000th liver transplant, a milestone that very few centers nationwide have achieved. And Mayo Clinic's Arizona campus completed its 1,000th liver transplant.

Liver transplant outcomes compare favorably with the national average.

Mayo Clinic in Rochester, Minn., ranks No. 1 for digestive disorders in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic in Scottsdale, Ariz., and Mayo Clinic in Jacksonville, Fla., are ranked among the Best Hospitals for digestive disorders by U.S. News & World Report. Mayo Clinic also ranks among the Best Children's Hospitals for digestive disorders.

Learn more about Mayo Clinic's quality rankings.

Aug. 23, 2016
  1. Scientific Registry of Transplant Recipients. April 11, 2016.
  2. U.S. News & World Report. U.S. News Best Hospitals 2015-16. Accessed Feb. 22, 2016.
  3. Barbara Woodward Lips Patient Education Center. Liver transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2013.
  4. Eggebraaten KR (expert opinion). Mayo Clinic, Rochester, Minn. May 23, 2016.
  5. Barbara DW, et al. The perioperative management of patients undergoing combined heart-liver transplantation. Transplantation. 2015;99:139.
  6. Bulatao IG, et al. Avoiding stay in the intensive care unit after liver transplantation: A score to assign location of care. American Journal of Transplantation. 2014;14:2088.
  7. Heimbach JK (expert opinion). Mayo Clinic, Rochester, Minn. June 28, 2016.
  8. Stulak JM, et al. Combined heart and abdominal organ transplantation: Excellent outcomes gained from a unique experience. Journal of Heart and Lung Transplantation. 2014;33:S278.
  9. Ibrahim SH (expert opinion). Mayo Clinic, Rochester, Minn. June 14, 2016.
  10. Glorioso JM, et al. Pivotal preclinical trial of the spheroid reservoir bioartificial liver. Journal of Hepatology. 2015;63:388.
  11. Heimbach JK, et al. Combined liver transplantation and gastric sleeve resection for patients with medically complicated obesity and end-stage liver disease. American Journal of Transplantation. 2013;13:363.
  12. Murad SD, et al. Long-term clinical and radiological follow up of living liver donors. Liver Transplantation. In press. Accessed May 11, 2016.
  13. Murad SD, et al. Predictors of pretransplant dropout and posttransplant recurrence in patients with perihilar cholangiocarcinoma. Hepatology. 2012;56:973.
  14. Barbara Woodward Lips Patient Education Center. About your child's liver transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2009.
  15. Rizvi S, et al. Primary sclerosing cholangitis as a premalignant biliary tract disease: Surveillance and management. Clinical Gastroenterology and Hepatology. 2015;13:2152.
  16. Taner T, et al. Decreased chronic cellular and antibody-mediated injury in the kidney following simultaneous liver-kidney transplantation. Kidney International. 2016;89:909.
  17. Watt KD, et al. A practical guide to the management of HCV infection following liver transplantation. American Journal of Transplantation. 2009;9:1707.
  18. Rosen CB, et al. Liver transplantation for cholangiocarcinoma. Transplant International. 2010;23:692.
  19. Raichlin E, et al. Combined heart and liver transplantation: A single-center experience. Transplantation. 2009;88:219.
  20. Nagourney E. 'Domino' transplants: Rare and risky. The New York Times. Accessed May 12, 2016.
  21. Kitchens WH. Domino liver transplantation: Indications, techniques, and outcomes. Transplantation Reviews. 2011;25:167.
  22. Yu Y, et al. Cell therapies for liver diseases. Liver Transplantation. 2012;18:9.
  23. Croome KP, et al. The use of donation after cardiac death allografts does not increase recurrence of hepatocellular carcinoma. American Journal of Transplantation. 2015;15:2704.
  24. De Assuncao TM, et al. Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes. Laboratory Investigation. 2015;95:684.
  25. Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Feb. 15, 2016.
  26. Brown AY. Allscripts EPSi. Mayo Clinic, Rochester, Minn. March 22, 2016.
  27. Cook AJ. Allscripts EPSi. Mayo Clinic, Rochester, Minn. May 2, 2014.
  28. Krowka MJ, et al. International Liver Transplant Society practice guidelines: Diagnosis and management of hepatopulmonary syndrome and portopulmonary hypertension. Transplantation. 2016;100:1440.
  29. Patel K, et al. FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus. World Journal of Gastroenterology. 2011;17:4581.
  30. Singh S, et al. Magnetic resonance elastography for staging liver fibrosis in non-alcoholic fatty liver disease: A diagnostic accuracy systematic review and individual participant data pooled analysis. European Radiology. 2016;26:1431.
  31. Han L, et al. Extracorporeal liver support and liver transplant for patients with acute-on-chronic liver failure. Seminars in Liver Disease. 2016;36:153. Accessed June 29, 2016.
  32. Gallagher C. Transplant genomics enters collaboration with Mayo Clinic (news release). Mayo Clinic, Rochester, Minn. June 27, 2016.
  33. Heilman RL (expert opinion). Mayo Clinic, Phoenix/Scottsdale, Ariz. June 24, 2016.