Treatments and drugs

By Mayo Clinic Staff

There's no cure for mixed connective tissue disease, but medication can help manage the signs and symptoms of the disease. Mild forms of mixed connective tissue disease may not require treatment. You may require treatment only during flares or, if you have a more serious form of the disease, you may require continuous medication.


The type of medication prescribed depends on the severity of your disease and the symptoms you have. Medications may include:

  • Corticosteroids. Drugs such as prednisone help control your immune function, keeping it from attacking healthy cells, and suppress inflammation. Side effects can include mood swings, weight gain, high blood sugar, increased blood pressure, weakened bones and cataracts.
  • Other immunosuppressants. Other treatments may be based on your signs and symptoms. For instance, if the symptoms you're experiencing are similar to those of lupus, your doctor may suggest trying medications typically prescribed for people with lupus.
May. 30, 2012

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