Melanoma, the most serious type of skin cancer, develops in the cells (melanocytes) that produce melanin the pigment that gives your skin its color. Melanoma can also form in your eyes and, rarely, in internal organs, such as your intestines.
The exact cause of all melanomas isn't clear, but exposure to ultraviolet (UV) radiation from sunlight or tanning lamps and beds increases your risk of developing melanoma. Limiting your exposure to UV radiation can help reduce your risk of melanoma.
The risk of melanoma seems to be increasing in people under 40, especially women. Knowing the warning signs of skin cancer can help ensure that cancerous changes are detected and treated before the cancer has spread. Melanoma can be treated successfully if it is detected early.
Apr. 15, 2014
- What you need to know about melanoma and other skin cancers. National Cancer Institute. http://www.cancer.gov/cancertopics/wyntk/skin. Accessed Nov. 6, 2013.
- Niederhuber JE, et al., eds. Abeloff's Clinical Oncology. 5th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2014. http://www.clinicalkey.com. Accessed Nov. 6, 2013.
- Habif TP. Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 5th ed. Edinburgh, U.K.; New York, N.Y.: Mosby Elsevier; 2010. http://www.clinicalkey.com. Accessed Nov. 6, 2013.
- Tafinlar (prescribing information). Research Triangle Park, N.C.: GlaxoSmithKline; 2013. http://www.tafinlar.com. Accessed Nov. 8, 2013.
- Yervoy (prescribing information). Princeton, N.J.: Bristol-Myers Squibb Company; 2013. http://www.yervoy.com. Accessed Nov. 8, 2013.
- Intraocular (eye) melanoma treatment (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/intraocularmelanoma/patient. Accessed Nov. 6, 2013.
- Smith RA, et al. Cancer screening in the United States, 2013: A review of current American Cancer Society guidelines and current issues in cancer screening, and new guidance on cervical cancer screening and lung cancer screening. CA A Cancer Journal for Clinicians. 2013;63:87.
- Skin examinations. SkinCancerNet. http://www.skincarephysicians.com/skincancernet/skin_examinations.html. Accessed Nov. 6, 2013.
- Preventive services for adults. Bloomington, Minn.: Institute for Clinical Systems Improvement. https://www.icsi.org/guidelines__more/catalog_guidelines_and_more/catalog_guidelines/catalog_prevention__screening_guidelines/preventive_services_for_adults. Accessed Nov. 6, 2013.
- Zelboraf (prescribing information). South San Francisco, Calif.: Genentech Inc.; 2013. http://www.zelboraf.com. Accessed Nov. 8, 2013.
- U.S. Preventive Services Task Force. Screening for skin cancer: U.S. Preventive Services Task Force Recommendation statement. Annals of Internal Medicine. 2009;150:188.
- Melanoma. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed Nov. 6, 2013.
- Reed KB, et al. Increasing incidence of melanoma among young adults: An epidemiological study in Olmsted County, Minnesota. Mayo Clinic Proceedings. 2012;87:328.
- Golden AK. Decision Support System. Mayo Clinic, Rochester, Minn. Aug. 2, 2013.
- Gibson LE (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 12, 2013.
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