By Mayo Clinic Staff

Lymphoma is a cancer of the lymphatic system, the body's disease-fighting network.

The lymphatic system includes the lymph nodes (lymph glands), spleen, thymus gland and bone marrow. Lymphoma can affect all those areas as well as other organs throughout the body.

Many types of lymphoma exist. The main categories of lymphoma are:

  • Hodgkin's lymphoma
  • Non-Hodgkin's lymphoma

What lymphoma treatment is best for you depends on your lymphoma type, the severity of your lymphoma and your preferences. Lymphoma treatment may involve chemotherapy, biological therapy medications, radiation therapy or a stem cell transplant.

  • Collaboration. At Mayo Clinic, specialists in hematology, radiation oncology, radiology, transplant, dermatology and other specialties work together to provide whole-person care for those with lymphoma.

    Mayo Clinic's integrated group practice gives people with lymphoma rapid access to the expertise needed to treat their condition.

  • Experience. Mayo Clinic hematologists have extensive experience treating all types of lymphoma, including common forms and rare types of lymphoma. Each year, Mayo Clinic doctors care for more than 3,900 people with lymphoma.
  • Access to the latest research. Mayo Clinic is a leader in lymphoma research. Mayo Clinic's role in lymphoma research provides access to the latest treatments, including clinical trials to test new therapies for the disease.
  • A full range of treatment options to consider. Mayo Clinic doctors will work with you to review all of your treatment options and choose the treatment that best suits your needs and goals. The range of treatment offered to people with lymphoma includes bone marrow transplant, chemotherapy, radiation therapy, targeted therapy and biological therapy, among others.
  • Services for lymphoma survivors. Mayo Clinic offers services for people who have completed lymphoma treatment through cancer survivorship clinics. The lymphoma survivorship clinic offers evaluation for physical and psychological side effects, as well as provides plans for follow-up care and healthy living after cancer treatment.
  • Comprehensive cancer center. Mayo Clinic Cancer Center meets strict standards for a National Cancer Institute comprehensive cancer center, which recognizes scientific excellence and a multidisciplinary approach to cancer prevention, diagnosis and treatment.

Mayo Clinic in Rochester, Minn., Mayo Clinic in Jacksonville, Fla., and Mayo Clinic in Scottsdale, Ariz., are ranked among the Best Hospitals for cancer by U.S. News & World Report.

Mayo Clinic doctors have extensive experience diagnosing and treating all types of lymphoma, including very rare types. This knowledge, combined with the latest diagnosis and treatment innovations, means Mayo Clinic doctors are equipped to provide you with exactly the care you need.

Mayo Clinic provides care for people with a variety of lymphoma types, including:

Non-Hodgkin's lymphoma, which includes:

  • Diffuse large B-cell lymphoma
  • Follicular lymphoma
  • Chronic lymphocytic leukemia and the related small lymphocytic lymphoma
  • Cutaneous T-cell lymphoma, which occurs in two main types, mycosis fungoides and Sezary syndrome
  • Marginal zone lymphoma
  • Peripheral T-cell lymphoma
  • Mantle cell lymphoma
  • Primary mediastinal B-cell lymphoma
  • Burkitt lymphoma
  • Lymphoplasmacytic lymphoma (which includes Waldenstrom macroglobulinemia)

Hodgkin's lymphoma (formerly called Hodgkin's disease), which includes:

  • Classical Hodgkin's lymphoma
  • Nodular lymphocyte-predominant Hodgkin's lymphoma

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people. In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Specialists in oncology/hematology at Mayo Clinic oversee the care of people with lymphoma. Other specialists may be involved in your care, as needed.

800-446-2279 (toll-free)
8 a.m. to 5 p.m. Mountain Standard Time, Monday through Friday

Specialists in oncology/hematology at Mayo Clinic oversee the care of people with lymphoma. Other specialists may be involved in your care, as needed.

For appointments or more information, call the Central Appointment Office at 904-953-0853 8 a.m. to 5 p.m. Eastern time, Monday through Friday or complete an online appointment request form.

Specialists in hematology at Mayo Clinic oversee the care of people with lymphoma. Other specialists may be involved in your care, as needed.

7 a.m. to 6 p.m. Central time, Monday through Friday

See information on patient services at the three Mayo Clinic locations, including transportation options and lodging.

Mayo Clinic is a leader in lymphoma research. The hematologic malignancies program conducts research related to lymphoma and other blood and bone marrow cancers.

The National Cancer Institute has designated Mayo Clinic a comprehensive cancer center and helps fund Mayo Clinic's lymphoma research through a Specialized Program of Research Excellence (SPORE) grant. Mayo applies that research to developing more effective and less toxic treatments for all forms of lymphoma. Mayo Clinic conducts many clinical trials to test new therapies for the disease.

Cancer research is conducted in coordination with the Mayo Clinic Cancer Center. The Mayo Clinic Cancer Center receives funding from the National Cancer Institute and is designated as a comprehensive cancer center — recognition for an institution's scientific excellence and multidisciplinary resources focused on cancer prevention, diagnosis and treatment.


See a list of publications by Mayo Clinic authors on lymphoma on PubMed, a service of the National Library of Medicine.

May 15, 2015