There is no cure for Ehlers-Danlos syndrome, but treatment can help you manage your symptoms and prevent further complications.
Your doctor may prescribe drugs to help you control:
- Pain. If over-the-counter pain relievers — such as ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve) — aren't enough, your doctor may prescribe stronger medications for your joint or muscle pain.
- Blood pressure. Because blood vessels are more fragile in some types of Ehlers-Danlos syndrome, your doctor may want to reduce the stress on the vessels by keeping your blood pressure low.
Joints with weak connective tissue are more likely to dislocate. Exercises to strengthen the muscles around a joint can help stabilize the joint. Your physical therapist might also recommend specific braces to help prevent joint dislocations.
Surgical and other procedures
In rare cases, surgery is recommended to repair joints damaged by repeated dislocations. However, your skin and the connective tissue of the affected joint may not heal properly after the surgery.
Aug. 20, 2015
- Firestein GS, et al. Heritable diseases of connective tissue. In: Kelley's Textbook of Rheumatology. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2013. http://www.clinicalkey.com. Accessed June 30, 2015.
- Pauker SP, et al. Clinical manifestations and diagnosis of Ehlers-Danlos syndrome. http://www.uptodate.com/home. Accessed June 30, 2015.
- Goldsmith LA, et al., eds. Lipoid proteinosis and heritable disorders of connective tissue. In: Fitzpatrick's Dermatology in General Medicine. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com. Accessed June 30, 2015.
- Pauker SP, et al. Overview of the management of Ehlers-Danlos syndrome. http://www.uptodate.com/home. Accessed June 30, 2015.
- Ferri FF. Ehlers-Danlos syndrome. In: Ferri's Clinical Advisor 2016. Philadelphia, Pa.: Mosby Elsevier; 2016. https://www.clinicalkey.com. Accessed June 30, 2015.
- Ehlers Danlos syndrome. National Organization for Rare Disorders. http://rarediseases.org/rare-diseases/ehlers-danlos-syndrome. Accessed July 2, 2015.
- AskMayoExpert. Ehlers-Danlos syndrome. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
- An educator's guide: Meeting the needs of the Ehlers-Danlos child. Ehlers-Danlos National Foundation. http://ednf.org/patient-resource-library. Accessed July 2, 2015.
- Golden AK. Decision Support System. Mayo Clinic, Rochester, Minn. March 31, 2015.
- Deyle DR (expert opinion). Mayo Clinic, Rochester, Minn. Aug. 7, 2015.