Although depression may occur only one time during your life, usually people have multiple episodes of depression. During these episodes, symptoms occur most of the day, nearly every day and may include:
- Feelings of sadness, tearfulness, emptiness or hopelessness
- Angry outbursts, irritability or frustration, even over small matters
- Loss of interest or pleasure in most or all normal activities, such as sex, hobbies or sports
- Sleep disturbances, including insomnia or sleeping too much
- Tiredness and lack of energy, so even small tasks take extra effort
- Changes in appetite — often reduced appetite and weight loss, but increased cravings for food and weight gain in some people
- Anxiety, agitation or restlessness
- Slowed thinking, speaking or body movements
- Feelings of worthlessness or guilt, fixating on past failures or blaming yourself for things that aren't your responsibility
- Trouble thinking, concentrating, making decisions and remembering things
- Frequent or recurrent thoughts of death, suicidal thoughts, suicide attempts or suicide
- Unexplained physical problems, such as back pain or headaches
For many people with depression, symptoms usually are severe enough to cause noticeable problems in day-to-day activities, such as work, school, social activities or relationships with others. Other people may feel generally miserable or unhappy without really knowing why.
Depression symptoms in children and teens
Common signs and symptoms of depression in children and teenagers are similar to those of adults, but there can be some differences.
- In younger children, symptoms of depression may include sadness, irritability, clinginess, worry, aches and pains, refusing to go to school, or being underweight.
- In teens, symptoms may include sadness, irritability, feeling negative and worthless, anger, poor performance or poor attendance at school, feeling misunderstood and extremely sensitive, using drugs or alcohol, eating or sleeping too much, self-harm, loss of interest in normal activities, and avoidance of social interaction.
Children with attention-deficit/hyperactivity disorder (ADHD) can demonstrate irritability without sadness or loss of interest. However, major depression can occur with ADHD.
Depression symptoms in older adults
Depression is not a normal part of growing older, and it should never be taken lightly. Unfortunately, depression often goes undiagnosed and untreated in older adults, and they may feel reluctant to seek help. Symptoms of depression may be different or less obvious in older adults, such as:
- Memory difficulties or personality changes
- Physical aches or pain
- Fatigue, loss of appetite, sleep problems, aches or loss of interest in sex — not caused by a medical condition or medication
- Often wanting to stay at home, rather than going out to socialize or doing new things
- Suicidal thinking or feelings, especially in older men
When to see a doctor
If you feel depressed, make an appointment to see your doctor as soon as you can. If you're reluctant to seek treatment, talk to a friend or loved one, a health care professional, a faith leader, or someone else you trust.
When to get emergency help
If you think you may hurt yourself or attempt suicide, call 911 or your local emergency number immediately.
Also consider these options if you're having suicidal thoughts:
- Call your mental health specialist.
- Call a suicide hotline number — in the U.S., call the National Suicide Prevention Lifeline at 1-800-273-TALK (1-800-273-8255). Use that same number and press "1" to reach the Veterans Crisis Line.
- Seek help from your primary doctor or other health care provider.
- Reach out to a close friend or loved one.
- Contact a minister, spiritual leader or someone else in your faith community.
If a loved one or friend is in danger of attempting suicide or has made an attempt:
July 07, 2016
- Make sure someone stays with that person
- Call 911 or your local emergency number immediately
- Or, if you can do so safely, take the person to the nearest hospital emergency room
- Depressive disorders. In: Diagnostic and Statistical Manual of Mental Disorders DSM-5. 5th ed. Arlington, Va.: American Psychiatric Association; 2013. http://www.psychiatryonline.org. Accessed June 5, 2015.
- Depression. National Institute of Mental Health. http://www.nimh.nih.gov/health/topics/depression/index.shtml. Accessed June 6, 2015.
- Depression. National Alliance on Mental Illness. https://www.nami.org/Learn-More/Mental-Health-Conditions/Depression/Overview. Accessed June 6, 2015.
- Lyness JM. Unipolar depression in adults: Assessment and diagnosis. http://www.uptodate.com/home. Accessed June 7, 2015.
- Ciechanowski P. Unipolar major depression in adults: Choosing initial treatment. http://www.uptodate.com/home. Accessed June 7, 2015.
- Cook AJ. Decision Support System. Mayo Clinic, Rochester, Minn. April 17, 2015.
- Bipolar and related disorders. In: Diagnostic and Statistical Manual of Mental Disorders DSM-5. 5th ed. Arlington, Va.: American Psychiatric Association; 2013. http://www.psychiatryonline.org. Accessed June 7, 2015.
- Ravindran AV, et al. Complementary and alternative therapies as add-on to pharmacotherapy for mood and anxiety disorders: A systematic review. Journal of Affective Disorders. 2013;150:707.
- Marchand WR. Mindfulness-based stress reduction, mindfulness-based cognitive therapy, and Zen meditation for depression, anxiety, pain, and psychological distress. Journal of Psychiatric Practice. 2012;18:233.
- Natural medicines in the clinical management of depression. Natural Medicines Comprehensive Database. http://naturaldatabase.therapeuticresearch.com/(X(1)S(sfvi05ehv0kkun55qwgkix55))/ce/CECourse.aspx?cs=MAYO&pm=5&s=nd&pc=09-30&searchid=51946815#keywordanchor. Accessed June 7, 2015.
- Raglio A, et al. Effects of music and music therapy on mood in neurological patients. World Journal of Psychiatry. 2015;5:68.
- FYI: Understanding depression and effective treatment. American Psychological Association. http://www.apa.org/helpcenter/understanding-depression.aspx. Accessed June 5, 2015.
- Uttley L, et al. Systematic review and economic modelling of the clinical effectiveness and cost-effectiveness of art therapy among people with non-psychotic mental health disorders. Health Technology Assessment. 2015;19:1.
- Research report: Psychiatry and psychology, 2014-2015. Mayo Clinic. http://www.mayo.edu/pmts/mc0700-mc0799/mc0710-11.pdf. Accessed June 5, 2015.
- Viibryd (prescribing information). Cincinnati, OH.: Forest Pharmaceuticals; 2015. http://www.viibryd.com/. Accessed June 7, 2015.
- Stewart D, et al. Risks of antidepressants during pregnancy: Selective serotonin reuptake inhibitors (SSRIs). http://www.uptodate.com/home. Accessed June 8, 2015.
- Rohren CH (expert opinion). Mayo Clinic, Rochester, Minn. June 11, 2015.
- Hoban CL, et al. A comparison of patterns of spontaneous adverse drug reaction reporting with St. John's wort and fluoxetine during the period 2000-2013. Clinical and Experimental Pharmacology and Physiology. 2015;42:747.
- Hall-Flavin DK (expert opinion). Mayo Clinic, Rochester, Minn. July 1, 2015.